Patents by Inventor Yves Ribeill
Yves Ribeill has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7166594Abstract: Group A streptogramin derivatives of general formula (I) in which: R1 represents a halogen atom or an azido or thiocyanato radical, R2 represents a hydrogen atom or a methyl or ethyl radical, R3 represents a hydrogen atom, or the residue of an aliphatic, cycloaliphatic, aromatic, araliphatic, heterocyclic or heterocyclylaliphatic ester which may be substituted, and the bond --- represents a single bond (stereochemistry 27R) or a double bond, as well as its salts when they existType: GrantFiled: December 6, 2002Date of Patent: January 23, 2007Assignee: Aventis Pharma S.A.Inventors: Daniel Achard, Eric Bacque, Jean-Claude Barriere, Jean Bouquerel, Pascal Desmazeau, Serge Grisoni, Jean-Pierre Leconte, Yves Ribeill, Baptiste Ronan
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Patent number: 7067548Abstract: A method of controlling parasites in or on an animal comprising orally administering to the animal a parasiticidally effective, substantially non-emetic 1-arylpyrazole.Type: GrantFiled: July 3, 2003Date of Patent: June 27, 2006Assignee: Rhone-Poulenc AgroInventors: Scot Kevin Huber, Yves Ribeill, Susan Marie McComb, Michael James Malaska, David Teh-Wei Chou, Adalberto Perez de Leon
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Patent number: 7019110Abstract: Group B streptogramin derivatives of general formula (I) are disclosed: wherein Ra, Rb, Rc, Rd, R1, R2 and Y are as defined in the description, including preparation methods and compositions containing the same. Such derivatives are particularly useful as antimicrobial agents, optionally combined with at least one group A streptogramin derivative.Type: GrantFiled: March 2, 2004Date of Patent: March 28, 2006Assignee: Aventis Pharma S.A.Inventors: Pascal Desmazeau, Gilles Doerflinger, Yves Ribeill, Eric Bacque, Jean-Claude Barriere, Gilles Dutruc-Rosset, Gérard Puchault
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Patent number: 6958383Abstract: Group B streptogramin derivatives of general formula (I): wherein Ra, Rb, Rc, Rd, R1, R2 and Y are as defined in the description, including preparation methods and compositions containing same. Such derivatives are particularly useful as antimicrobial agents, optionally combined with at least one group A streptogramin derivative.Type: GrantFiled: June 5, 2002Date of Patent: October 25, 2005Assignee: Aventis Pharma S. A.Inventors: Pascal Desmazeau, Gilles Doerflinger, Yves Ribeill, Eric Bacque, Jean-Claude Barriere, Gilles Dutruc-Rosset, Gérard Puchault
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Publication number: 20040266667Abstract: Group B streptogramin derivatives of general formula (I) are disclosed: 1Type: ApplicationFiled: March 2, 2004Publication date: December 30, 2004Applicant: Aventis Pharma S.A.Inventors: Pascal Desmazeau, Gilles Doerflinger, Yves Ribeill, Eric Bacque, Jean-Claude Barriere, Gilles Dutruc-Rosset, Gerard Puchault
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Patent number: 6815437Abstract: Group A streptogramin derivatives of formula (I): the salts thereof, and mixtures of stereoisomers thereof, as well as processes for preparing them and pharmaceutical compositions comprising them are disclosed.Type: GrantFiled: January 27, 2000Date of Patent: November 9, 2004Assignee: Aventis Pharma S.A.Inventors: Alain Commerçon, Hervé Bouchard, Yves Ribeill, Eric Bacque, Baptiste Ronan, Jean-Claude Barriere, Gérard Puchault, Corinne Terrier
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Publication number: 20040010016Abstract: A method of controlling parasites in or on an animal comprising orally administering to the animal a parasiticidally effective, substantially non-emetic 1-arylpyrazole.Type: ApplicationFiled: July 3, 2003Publication date: January 15, 2004Applicant: Aventis CropScience, S.A.Inventors: Scot Kevin Huber, Yves Ribeill, Susan Marie McComb, Michael James Malaska, David Teh-Wei Chou, Adalberto Perez de Leon
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Patent number: 6630499Abstract: A method of controlling parasites in or on an animal comprising orally administering to the animal a parasiticidally effective, substantially non-emetic 1-arylpyrazole.Type: GrantFiled: January 15, 2003Date of Patent: October 7, 2003Assignee: Aventis CropScience, S.A.Inventors: Scot Kevin Huber, Yves Ribeill, Susan Marie McComb, Michael James Malaska, David Teh-Wei Chou, Adalberto Perez de Leon
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Publication number: 20030149004Abstract: Group A streptogramin derivatives of general formula (I) in which:Type: ApplicationFiled: December 6, 2002Publication date: August 7, 2003Applicant: Aventis Pharma S.A.Inventors: Daniel Achard, Eric Bacque, Jean-Claude Barriere, Jean Bouquerel, Pascal Desmazeau, Serge Grisoni, Jean-Pierre Leconte, Yves Ribeill, Baptiste Ronan
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Patent number: 6569854Abstract: Group A streptogramin derivatives of general formula (I) in which: R1 represents a halogen atom or an azido or thiocyanato radical, R2 represents a hydrogen atom or a methyl or ethyl radical, R3 represents a hydrogen atom, or the residue of an aliphatic, cycloaliphatic, aromatic, araliphatic, heterocyclic or heterocyclylaliphatic ester which may be substituted, and the bond - - - represents a single bond (stereochemistry 27R) or a double bond, as well as its salts when they exist.Type: GrantFiled: June 30, 2000Date of Patent: May 27, 2003Assignee: Aventis Pharma S.A.Inventors: Daniel Achard, Eric Bacque, Jean-Claude Barriere, Jean Bouquerel, Pascal Desmazeau, Serge Grisoni, Jean-Pierre Leconte, Yves Ribeill, Baptiste Ronan
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Patent number: 6531501Abstract: A method of controlling parasites in or on an animal comprising orally administering to the animal a parasiticidally effective, substantially non-emetic 1-arylpyrazole.Type: GrantFiled: June 9, 2000Date of Patent: March 11, 2003Assignee: Aventis CropScience, S.A.Inventors: Scot Kevin Huber, Yves Ribeill, Susan Marie McComb, Michael James Malaska, David Teh-Wei Chou, Adalberto Perez de Leon
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Patent number: 6500609Abstract: Devices and processes for synthesizing, purifying and analyzing large numbers of compounds for use in combinatorial libraries, are disclosed. The processes involve generating a series of compounds in multi-well plates or multi-tube racks, purifying the reaction mixtures, analyzing the purified compounds, and optionally performing bioassays on the compounds. The information regarding the compounds is stored in a central database. The devices include one or more multi-tube arrays, a purification device, means for transferring the contents of the tubes, a solvent evaporator, analytical instrumentation, and, optionally, a weighing instrument. The multi-tube array(s) optionally include a cover, which can be placed on or removed from the array by computer control. By correlating the orientation of tubes from one stage to the next, it is possible to use a single bar code or other identifying mark for each multi-tube array rather than for each individual tube.Type: GrantFiled: February 11, 1999Date of Patent: December 31, 2002Assignee: Scynexis Chemistry & Automation, Inc.Inventors: Yves Ribeill, Pierre Monnet, Jaleh Azmi Abedi, Henry David Smith, III, Susan Marie McComb
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Publication number: 20020151676Abstract: Group B streptogramin derivatives of general formula (I): 1Type: ApplicationFiled: June 5, 2002Publication date: October 17, 2002Applicant: Aventis Pharma S.A.Inventors: Pascal Desmazeau, Gilles Doerflinger, Yves Ribeill, Eric Bacque, Jean-Claude Barriere, Gilles Dutruc-Rosset, Gerard Puchault
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Patent number: 6160002Abstract: A method of controlling parasites in or on an animal comprising orally administering to the animal a parasitically effective, substantially non-emetic 1-arylpyrazole.Type: GrantFiled: December 10, 1999Date of Patent: December 12, 2000Assignee: Rhone-Poulenc AgroInventors: Scot Kevin Huber, Yves Ribeill, Susan Marie McComb, Michael James Malaska, David Teh-Wei Chou, Adalberto Perez de Leon
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Patent number: 6057454Abstract: A compound of formula (II): ##STR1## in which R is a hydrogen atom or a carboxy, alkoxycarbonyl, --CO--NR.sub.4 R.sub.5, --PO.sub.3 H.sub.2 or --CH.sub.2 OH radical, and R.sub.1 is an -alk-NH.sub.2, -alk-NH--CO--R.sub.3, -alk-COOR.sub.4, -alk-CO--NR.sub.5 R.sub.6 or --CO--NH--R.sub.7 radical. The compounds of formula (II) can be used to prepare compounds of formula (I): ##STR2## in which R and R.sub.1 have the same meanings as above. The compounds of formula (I) have valuable pharmacological properties and are antagonists of the .alpha.-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor, also known as the quisqualate receptor. The compounds of formula (I) are also non-competitive antagonists of the N-methyl-D-aspartate (NMDA) receptor and more specifically are ligands for NMDA receptor glycine modulator sites.Type: GrantFiled: December 4, 1998Date of Patent: May 2, 2000Assignee: Rhone-Poulenc Rorer S.A.Inventors: Jean-Claude Aloup, Fran.cedilla.ois Audiau, Michel Barreau, Dominique Damour, Arielle Genevois-Borella, Jean-Claude Hardy, Patrick Jimonet, Franco Manfre, Serge Mignani, Patrick Nemecek, Yves Ribeill
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Patent number: 5922716Abstract: Compounds of formula (I): ##STR1## wherein R represents a CR.sub.4 R.sub.5, CHR.sub.6, or C.dbd.R.sub.7 radical and R.sub.3 represents an oxygen atom, salts thereof, the preparation thereof and drugs containing same. The compounds of formula (I) have valuable pharmacological properties and are alpha-amino-3-hydroxy-5-methyl-4-osoxaziepropionic acid (AMPA) receptor antagonists, said receptor also being known as the quisqualate receptor. Furthermore, the compounds of formula (I) are non-competitive N-methyl-D-aspartate (NMDA) receptor antagonists, and particularly NMDA receptor glycine modulation site ligands.Type: GrantFiled: September 27, 1996Date of Patent: July 13, 1999Assignee: Rhone-Poulenc Rorer S.A.Inventors: Jean-Claude Aloup, Fran.cedilla.ois Audiau, Michel Barreau, Dominique Damour, Arielle Genevois-Borella, Patrick Jimonet, Serge Mignani, Yves Ribeill
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Patent number: 5902803Abstract: Compounds of formula (I), wherein R is a hydrogen atom or a carboxy, alkoxycarbonyl, --CO--NR.sub.4 R.sub.5, --PO.sub.3 H.sub.2 or --CH.sub.2 OH radical, and R.sub.1 is an -alk-NH.sub.2, -alk-NH--CO--R.sub.3, -alk-COOR.sub.4, -alk-CO--NR.sub.5 R.sub.6 or --CO--NH--R.sub.7 radical. The compounds of formula (I) have valuable pharmacological properties and are antagonists of the .alpha.-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor also known as the quisqualate receptor. Furthermore, the compounds of formula (I) are non-competitive antagonists of the N-methyl-D-aspartame (NMDA) receptor and more specifically are ligands for NMDA receptor glycine modulator sites.Type: GrantFiled: October 3, 1997Date of Patent: May 11, 1999Assignee: Rhone-Poulenc Rorer S.A.Inventors: Jean-Claude Aloup, Fran.cedilla.ois Audiau, Michel Barreau, Dominique Damour, Arielle Genevois-Borella, Jean-Claude Hardy, Patrick Jimonet, Franco Manfre, Serge Mignani, Patrick Nemecek, Yves Ribeill
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Patent number: 5807859Abstract: Pharmaceutical compositions containing, as the active principle, compounds of formula (I): ##STR1## wherein R, R.sub.1 and R.sub.2 are as defined in the description, or salts thereof, the novel compounds of formula (I), and the preparation thereof. The compounds of formula (I) have valuable pharmacological properties and are alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonists, this receptor also being known as the quisqualate receptor. Furthermore, the compounds of formula (I) are non-competitive N-methyl-D-aspartate (NDMA) receptor antagonists, and particularly NMDA receptor glycine modulation site ligands.Type: GrantFiled: September 27, 1996Date of Patent: September 15, 1998Assignee: Rhone-Poulenc Rorer S.A.Inventors: Jean-Claude Aloup, Francois Audiau, Michel Barreau, Dominique Damour, Arielle Genevois-Borella, Patrick Jimonet, Serge Mignani, Yves Ribeill
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Patent number: 5789406Abstract: The compounds of formula (I) ##STR1## wherein R, R.sub.1 and R.sub.2 are defined in the disclosure, and salts thereof.The compounds of formula (I) are non-competitive N-methyl-D-asparate (NMDA) receptor antagonists, particularly NMDA receptor glycine modulation site ligands, and are alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonists, this receptor is also known as the quisqualate receptor.Type: GrantFiled: September 27, 1996Date of Patent: August 4, 1998Assignee: Rhone-Poulenc Rorer S.A.Inventors: Jean-Claude Aloup, Fran.cedilla.ois Audiau, Michel Barreau, Dominique Damour, Arielle Genevois-Borella, Patrick Jimonet, Serge Mignani, Yves Ribeill
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Patent number: 5777114Abstract: Compounds of formula (I): ##STR1## wherein R.sub.3 and R.sub.4, taken together with the carbon atom to which they are attached, form (a) a 2- or 3-pyrrolidine ring, a 2- or 4-piperidine ring or a 2-azacycloheptane ring, said rings being optionally substituted at the nitrogen atom by an alkyl, --CHO, --COOR.sub.11, --CO--alk--COOR.sub.6, --CO--alk--NR.sub.6 R.sub.12, --CO--alk--CONR.sub.6 R.sub.8, --CO--COOR.sub.6, --CO--CH.sub.2 --O--CH.sub.2 --COOR.sub.6, --CO--CH.sub.2 --S--CH.sub.2 --COOR.sub.6, --CO--CH.dbd.CH--COOR.sub.6, CO--alk, --CO--Ar", --CO--alk--Ar", --CO--NH--Ar", --CO--NH--alk--Ar", --CO--Het, --CO--alk--Het, --CO--NH--Het, --CO--NH--alk--Het, --CO--NH.sub.2, --CO--NH--alk, --CO--N(alk)alk', --CS--NH.sub.2, --CS--NH--alk, --CS--NH--Ar", --CS--NH--Het, --alk--Het, --alk--NR.sub.6 R.sub.8, --alk--COOR.sub.6, --alk--CO--NR.sub.6 R.sub.8, --alk--Ar", --SO.sub.2 --alk or --SO.sub.Type: GrantFiled: June 30, 1997Date of Patent: July 7, 1998Assignee: Rhone-Poulenc Rorer S.A.Inventors: Jean-Claude Aloup, Fran.cedilla.ois Audiau, Michel Barreau, Dominique Damour, Arielle Genevois-Borella, Patrick Jimonet, Serge Mignani, Yves Ribeill