Patents by Inventor Yvon Derrien

Yvon Derrien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9920089
    Abstract: The present invention relates to a process for the preparation of 17-substituted steroids and, more particularly, to an improved method of preparing micro size abiraterone or derivatives thereof in high yield and purity by means of a spherical agglomeration process.
    Type: Grant
    Filed: April 11, 2014
    Date of Patent: March 20, 2018
    Assignee: ZACH SYSTEM
    Inventors: Patricia Poirier, Yvon Derrien, Massimiliano Forcato, Livius Cotarca, Pierrick Morice
  • Patent number: 9353145
    Abstract: The present invention relates to a process for the preparation of 17-substituted steroids and, more particularly, to an improved method of synthesizing abiraterone or derivatives thereof in high yield and purity by means of a key 3-formate intermediate.
    Type: Grant
    Filed: October 9, 2012
    Date of Patent: May 31, 2016
    Assignee: ZACH SYSTEM
    Inventors: Yvon Derrien, Patricia Poirier, Massimiliano Forcato, Tony Pintus, Livius Cotarca, Sebastien Meunier, Laurence Graindorge
  • Publication number: 20160083416
    Abstract: The present invention relates to a process for the preparation of 17-substituted steroids and, more particularly, to an improved method of preparing micro size abiraterone or derivatives thereof in high yield and purity by means of a spherical agglomeration process.
    Type: Application
    Filed: April 11, 2014
    Publication date: March 24, 2016
    Applicant: ZACH SYSTEM
    Inventors: Patricia POIRIER, Yvon DERRIEN, Massimiliano FORCATO, Livius COTARCA, Pierrick MORICE
  • Patent number: 8981127
    Abstract: The present invention relates to a process for the preparation of nebivolol and, more particularly, to an improved process of synthesizing an alpha-haloketone of formula a key intermediate in the preparation of nebivolol.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: March 17, 2015
    Assignee: Zach System
    Inventors: Yvon Derrien, Eric Chenard, Alain Burgos
  • Publication number: 20140256932
    Abstract: The present invention relates to a process for the preparation of 17-substituted steroids and, more particularly, to an improved method of synthesizing abiraterone or derivatives thereof in high yield and purity by means of a key 3-formate intermediate.
    Type: Application
    Filed: October 9, 2012
    Publication date: September 11, 2014
    Applicant: ZACH SYSTEM
    Inventors: Yvon Derrien, Patricia Poirier, Massimiliano Forcato, Tony Pintus, Livius Cotarca, Sebastien Meunier, Laurence Graindorge
  • Publication number: 20110237808
    Abstract: The present invention relates to a process for the preparation of nebivolol and, more particularly, to an improved process of synthesizing an alpha-haloketone of formula a key intermediate in the preparation of nebivolol.
    Type: Application
    Filed: September 22, 2009
    Publication date: September 29, 2011
    Applicant: ZACH SYSTEM
    Inventors: Yvon Derrien, Eric Chenard, Alain Burgos
  • Patent number: 7456320
    Abstract: A process for the preparation of optically active substituted alpha-amino-indane derivatives of formula (I), which include: an asymmetric hydrogenation reaction of an en-amide derivative of formula (III) in presence of hydrogen and an optically active catalyst, in order to obtain an amide derivative of formula (II), a hydrolysis reaction of the amide derivative of formula (II) obtained in the previous step, in order to obtain optically active substituted alpha-amino-indane derivatives of formula (I).
    Type: Grant
    Filed: February 21, 2005
    Date of Patent: November 25, 2008
    Assignee: ZaCh System
    Inventors: Blandine Bertrand, Sylvie Blanchet, Alain Burgos, Juliette Martin, Florence Perrin, Sonia Roussiasse, Yvon Derrien
  • Patent number: 7262326
    Abstract: A process for preparing indanylamine and aminotetralin derivatives from indanone or tetralone oximes by acylating the oximes with an organic anhydride, followed by catalytic hydrogenation in the presence of an organic anhydride with subsequent hydrolysis is described. The process is commercially feasible providing indanylamine and aminotetralin derivatives in high yield that are useful as intermediates in the production of therapeutically active compounds. Also described are novel intermediates, 1-indanone O-acetyl oximes and 1-tetralone O-acetyl oximes.
    Type: Grant
    Filed: September 7, 2005
    Date of Patent: August 28, 2007
    Assignee: Teva Pharmaceuticals Industries Ltd.
    Inventors: Sylvie Blanchet, Bertrand Blandine, Alain Burgos, Yvon Derrien, Marie-Laure Moreau
  • Publication number: 20070191640
    Abstract: A process is for the preparation of optically active substituted alpha-indanyl amide derivatives of formula (I), which include: an asymmetric hydrogenation reaction of an en-amide derivative of formula (III) in presence of hydrogen and an optically active catalyst, in order to obtain an amide derivative of formula (II), a hydrolysis reaction of the amide derivative of formula (II) obtained in the previous step, in order to obtain optically active-substituted alpha-indanyl amide derivatives of formula (I).
    Type: Application
    Filed: February 21, 2005
    Publication date: August 16, 2007
    Applicant: PPG-SIPSY
    Inventors: Blandine Bertrand, Sylvie Blanchet, Alain Burgos, Juliette Martin, Florence Perrin, Sonia Roussiasse, Yvon Derrien
  • Publication number: 20060052639
    Abstract: A process for preparing indanylamine and aminotetralin derivatives from indanone or tetralone oximes by acylating the oximes with an organic anhydride, followed by catalytic hydrogenation in the presence of an organic anhydride with subsequent hydrolysis is described. The process is commercially feasible providing indanylamine and aminotetralin derivatives in high yield that are useful as intermediates in the production of therapeutically active compounds. Also described are novel intermediates, 1-indanone O-acetyl oximes and 1-tetralone O-acetyl oximes.
    Type: Application
    Filed: September 7, 2005
    Publication date: March 9, 2006
    Applicant: Teva Pharmaceuticals USA, Inc.
    Inventors: Sylvie Blanchet, Bertrand Blandine, Alain Burgos, Yvon Derrien, Marie-Laure Moreau
  • Patent number: 6849741
    Abstract: A method for preparing a thiazolidinedione, oxazolidinedione or hydantoin compound of formula (I) from a compound of formula (II): wherein Q represents an oxygen atom or a sulfur atom; Q1 represents an oxygen atom or a sulfur atom; R1 and R2, which can be identical or different, represent a hydrogen atom, a C1-10 alkyl chain, a cycloalkyl, an alkylaryl, an arylalkyl; the alkyl, cycloalkyl, alkylaryl or arylalkyl groups being optionally substituted by an alkyl, an alkoxy or aryloxy, a halogen, a hydroxy, a sulfino, a sulfonyl, an amino such as NH2, NHR3, N(R3)2, wherein R3 represents an alkyl, an alkoxy or an alkylcarbonyl, reacting a compound of formula (II) with formic acid, either as a hydrogen donor in a hydrogen-transfer reaction or as a solvent in a hydrogenation reaction, in the presence of a catalyst containing a transition metal to obtain a corresponding compound of formula (I).
    Type: Grant
    Filed: August 7, 2003
    Date of Patent: February 1, 2005
    Assignee: PPG-SIPSY
    Inventors: Michel Bulliard, Yvon Derrien, Tony Pintus
  • Publication number: 20040059121
    Abstract: A method for preparing a thiazolidinedione, oxazolidinedione or hydantoin compound of formula (I) from a compound of formula (II): 1
    Type: Application
    Filed: August 7, 2003
    Publication date: March 25, 2004
    Applicant: PPG-SIPSY, a corporation of France
    Inventors: Michel Bulliard, Yvon Derrien, Tony Pintus