Patents by Inventor Yvon E. Cayre

Yvon E. Cayre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR CHARACTERIZING AND ISOLATING CIRCULATING TUMOR CELL SUBPOPULATIONS
    Publication number: 20190264289
    Abstract: Provided are methods and assays for cancer cell classification, cancer prognosis and treatment based on the isolation of circulating tumor cells and the characterization of their nuclear organization and telomere signatures.
    Type: Application
    Filed: March 4, 2019
    Publication date: August 29, 2019
    Inventors: Sabine Mai, Yvon E. Cayre, Janine Wechsler
  • Apparatus and method for isolating target cells from a fluid sample
    Patent number: 10379018
    Abstract: Systems, methods, and apparatus are disclosed for recovering one or more target cells from a fluid sample. A first chamber aligned with a first surface of a removable filter receives the fluid sample. The removable filter defines a plurality of pores configured to retain the one or more target cells on the first surface and/or in the plurality of pores, each pore of the plurality of pores having a first diameter smaller than a diameter of the one or more target cells in the first surface and a second diameter greater than the first diameter in a second surface of the removable filter. A second chamber comprises a hydrophilic microporous wick structure configured to contact the second surface of the removable filter and capillarize any non-target cells and fluid from the fluid sample, drawing them into the second chamber.
    Type: Grant
    Filed: December 7, 2015
    Date of Patent: August 13, 2019
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Robert J. Distel, Yvon E. Cayre
  • APPARATUS AND METHOD FOR ISOLATING TARGET CELLS FROM A FLUID SAMPLE
    Publication number: 20170336307
    Abstract: Systems, methods, and apparatus are disclosed for recovering one or more target cells from a fluid sample. A first chamber aligned with a first surface of a removable filter receives the fluid sample. The removable filter defines a plurality of pores configured to retain the one or more target cells on the first surface and/or in the plurality of pores, each pore of the plurality of pores having a first diameter smaller than a diameter of the one or more target cells in the first surface and a second diameter greater than the first diameter in a second surface of the removable filter. A second chamber comprises a hydrophilic microporous wick structure configured to contact the second surface of the removable filter and capillarize any non-target cells and fluid from the fluid sample, drawing them into the second chamber.
    Type: Application
    Filed: July 7, 2015
    Publication date: November 23, 2017
    Inventors: Robert J. DISTEL, Yvon E. CAYRE
  • Methods For Characterizing And Isolating Circulating Tumor Cell Subpopulations
    Publication number: 20140024591
    Abstract: Provided are methods and assays for cancer cell classification, cancer prognosis and treatment based on the isolation of circulating tumor cells and the characterization of their nuclear organization and telomere signatures.
    Type: Application
    Filed: April 24, 2013
    Publication date: January 23, 2014
    Inventors: Sabine Mai, Yvon E. Cayre, Janine Wechsler