Patents by Inventor Yvonne Jones

Yvonne Jones has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED SEMAPHORIN 3A, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF
    Publication number: 20230272020
    Abstract: Provided herein are modified forms of Semaphorin 3A (Sema3A) polypeptide having one or more amino acid substitutions and/or deletions compared to a wild type Sema3A protein. Further provided are nucleic acid molecules encoding the modified Sema3A polypeptide, compositions including the same and uses thereof in treating various immune-related conditions.
    Type: Application
    Filed: June 3, 2021
    Publication date: August 31, 2023
    Inventors: Zahava VADASZ, Elias TOUBI, Nasren EIZA, Adi SABAG, Gera NEUFELD, Ofra KESSLER, E. Yvonne JONES
  • Compounds which are inhibitors of Notum
    Patent number: 11634391
    Abstract: A compound for use in the treatment of a disease ameliorated by the inhibition of Notum of formula (I): (I)
    Type: Grant
    Filed: August 30, 2019
    Date of Patent: April 25, 2023
    Assignee: UCL Business LTD
    Inventors: Paul Vincent Fish, William Mahy, Nicky John Willis, Hannah Woodward, Benjamin N Atkinson, Elliott D Bayle, James Sipthorp, Edith Yvonne Jones, Yuguang Zhao, Luca Vecchia, Reinis Reinholds Ruza
  • COMPOUNDS
    Publication number: 20210171475
    Abstract: A compound for use in the treatment of a disease ameliorated by the inhibition of Notum of formula (I): (I)
    Type: Application
    Filed: August 30, 2019
    Publication date: June 10, 2021
    Inventors: Paul Vincent Fish, William Mahy, Nicky John Willis, Hannah Woodward, Benjamin N Atkinson, Elliott D Bayle, James Sipthorp, Edith Yvonne Jones, Yuguang Zhao, Luca Vecchia, Reinis Reinholds Ruza
  • Single Use Undergarment Device
    Publication number: 20200397061
    Abstract: A single use undergarment device for travel use includes a pair of underwear that is resiliently stretchable. The pair of underwear has a pair of leg openings that define a crotch area, which comprises fabric, that is positioned between the pair of leg openings.
    Type: Application
    Filed: June 19, 2019
    Publication date: December 24, 2020
    Inventor: Yvonne Jones
  • Methods of promoting neuronal outgrowth by gypican 2 that binds to receptor protein tyrosine phosphatase sigma
    Patent number: 9744188
    Abstract: Disclosed herein are methods of inducing neuronal outgrowth of a neuron. The methods comprise contacting the neuron with an agent that binds receptor protein tyrosine phosphatase ? (RPTP?), to thereby induce neuronal outgrowth of the neuron. The agent may induces clustering of RPTP? and/or inhibit binding of chondroitin sulfate proteoglycan (CSPG) to RPTP?. Examples of suitable agents are heparan sulfate proteoglycan, heparan sulfate, heparan sulfate oligosaccharides, or heparin oligosaccharides. Additional agents are also disclosed. The neuron can be a CNS neuron or peripheral neuron. Also disclosed herein are methods of treating neuronal injury in a subject comprising, administering to the subject an agent that binds RPTP?. Administration may be to a site of neuronal injury, to thereby induce neuronal outgrowth at the site of neuronal injury.
    Type: Grant
    Filed: February 17, 2012
    Date of Patent: August 29, 2017
    Assignees: PRESIDENT AND FELLOWS OF HARVARD COLLEGE, THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
    Inventors: John G. Flanagan, Yingjie Shen, Edith Yvonne Jones, Alexandru Radu Aricescu, Charlotte Hannah Coles
  • MOLECULAR SWITCH FOR NEURONAL OUTGROWTH
    Publication number: 20140045762
    Abstract: Disclosed herein are methods of inducing neuronal outgrowth of a neuron. The methods comprise contacting the neuron with an agent that binds receptor protein tyrosine phosphatase ? (RPTP?), to thereby induce neuronal outgrowth of the neuron. The agent may induces clustering of RPTP? and/or inhibit binding of chondroitin sulfate proteoglycan (CSPG) to RPTP?. Examples of suitable agents are heparan sulfate proteoglycan, heparan sulfate, heparan sulfate oligosaccharides, or heparin oligosaccharides. Additional agents are also disclosed. The neuron can be a CNS neuron or peripheral neuron. Also disclosed herein are methods of treating neuronal injury in a subject comprising, administering to the subject an agent that binds RPTP?. Administration may be to a site of neuronal injury, to thereby induce neuronal outgrowth at the site of neuronal injury.
    Type: Application
    Filed: February 17, 2012
    Publication date: February 13, 2014
    Applicants: THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY FO OXFORD, PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: John G. Flanagan, Yingjie Shen, Edith Yvonne Jones, Alexandru Radu Aricescu, Charlotte Hannah Bonn