Patents by Inventor Yvonne Stark
Yvonne Stark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230357398Abstract: The present disclosure provides novel fully human antibodies and antibody fragments specific for human CD3 epsilon.Type: ApplicationFiled: September 22, 2021Publication date: November 9, 2023Inventors: Andreas BÜLTMANN, Steffen RUNZ, Tschimegma BATAA, Markus MOOSMEIER, Nicole HAUBST, Jürgen KLATTIG, Yvonne STARK
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Patent number: 10919955Abstract: The present invention provides synthetic rodent antibody libraries, such as mouse or rat antibody libraries, as well as polypeptides, nucleic acids, vectors, host cells and methods used in conjunction with these libraries. The present invention also provides antibodies isolated from such libraries and variants of such antibodies.Type: GrantFiled: March 10, 2017Date of Patent: February 16, 2021Assignee: MORPHOSYS AGInventors: Josef Prassler, David Ott, Stefanie Thiel, Yvonne Stark, Ute Keck, Thomas Pietzonka, Hilmar Ebersbach
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Publication number: 20170183395Abstract: The present invention provides synthetic rodent antibody libraries, such as mouse or rat antibody libraries, as well as polypeptides, nucleic acids, vectors, host cells and methods used in conjunction with these libraries. The present invention also provides antibodies isolated from such libraries and variants of such antibodies.Type: ApplicationFiled: March 10, 2017Publication date: June 29, 2017Inventors: Josef Prassler, David Ott, Stefanie Thiel, Yvonne Stark, Ute Keck, Thomas Pietzonka, Hilmar Ebersbach
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Patent number: 9650432Abstract: The present invention provides synthetic rodent antibody libraries, such as mouse or rat antibody libraries, as well as polypeptides, nucleic acids, vectors, host cells and methods used in conjunction with these libraries. The present invention also provides antibodies isolated from such libraries and variants of such antibodies.Type: GrantFiled: January 28, 2011Date of Patent: May 16, 2017Assignee: MORPHOSYS AGInventors: Josef Prassler, David Ott, Stefanie Thiel, Yvonne Stark, Ute Keck, Thomas Pietzonka, Hilmar Ebersbach
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Patent number: 9541559Abstract: The present disclosure enables collections of variable heavy chain and variable light chain pairs comprising, in part, germline protein sequences that are pre-selected for functional properties relevant to developability, wherein the collections may be used to select against any antigen using, for example, phage display.Type: GrantFiled: April 2, 2014Date of Patent: January 10, 2017Assignee: MORPHOSYS AGInventors: Stefanie Urlinger, Thomas Tiller, Ingrid Schuster, Yvonne Stark
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Patent number: 9062097Abstract: The present invention relates to methods for the formation of inter-molecular disulphide bonds, including (poly)peptides/proteins, nucleic acids, vectors, host cells and bacteriophages used in these methods. Furthermore the invention relates to the use of this method for the improved display of (poly)peptides/proteins on the surface of bacteriophage particles.Type: GrantFiled: August 21, 2008Date of Patent: June 23, 2015Assignee: Morpho Sys AGInventors: Josef Prassler, Yvonne Stark
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Publication number: 20140206575Abstract: The present disclosure enables collections of variable heavy chain and variable light chain pairs comprising, in part, germline protein sequences that are pre-selected for functional properties relevant to developability, wherein the collections may be used to select against any antigen using, for example, phage display.Type: ApplicationFiled: April 2, 2014Publication date: July 24, 2014Applicant: MorphoSys AGInventors: Stefanie Urlinger, Thomas Tiller, Ingrid Schuster, Yvonne Stark
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Patent number: 8728981Abstract: The present disclosure enables collections of variable heavy chain and variable light chain pairs comprising, in part, germline protein sequences that are pre-selected for functional properties relevant to developability, wherein the collections may be used to select against any antigen using, for example, phage display.Type: GrantFiled: November 18, 2011Date of Patent: May 20, 2014Assignee: MorphoSys AGInventors: Stefanie Urlinger, Thomas Tiller, Ingrid Schuster, Yvonne Stark
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Publication number: 20130236902Abstract: The present disclosure enables collections of variable heavy chain and variable light chain pairs comprising, in part, germline protein sequences that are pre-selected for functional properties relevant to developability, wherein the collections may be used to select against any antigen using, for example, phage display.Type: ApplicationFiled: November 18, 2011Publication date: September 12, 2013Applicant: MorphoSys AGInventors: Stefanie Urlinger, Thomas Tiller, Ingrid Schuster, Yvonne Stark
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Patent number: 8367586Abstract: The present disclosure enables collections of variable heavy chain and variable light chain pairs comprising, in part, germline protein sequences that are pre-selected for functional properties relevant to developability, wherein the collections may be used to select against any antigen using, for example, phage display.Type: GrantFiled: November 18, 2011Date of Patent: February 5, 2013Assignee: MorphoSys AGInventors: Stefanie Urlinger, Thomas Tiller, Ingrid Schuster, Yvonne Stark
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Publication number: 20130030157Abstract: The present invention provides synthetic rodent antibody libraries, such as mouse or rat antibody libraries, as well as polypeptides, nucleic acids, vectors, host cells and methods used in conjunction with these libraries. The present invention also provides antibodies isolated from such libraries and variants of such antibodies.Type: ApplicationFiled: January 28, 2011Publication date: January 31, 2013Applicant: MORPHOSYS AGInventors: Josef Prassler, David Ott, Stefanie Thiel, Yvonne Stark, Ute Keck, Thomas Pietzonka, Hilmar Ebersbach
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Patent number: 8206977Abstract: A tricistronic vector (i.e., a vector capable of expressing three exogenous genes, which are not fused together, under the control of one promoter) effectively can encode an immunoglobulin-presenting polypeptide and two immunoglobulin (Ig) polypeptides. The encoded Ig-presenting polypeptide is able to associate with at least one of the Ig polypeptides via co-expressed associating agents. A vector according to the present invention particularly is suited for phage display technology, e.g., when the Ig-presenting polypeptide is a phage coat protein and the Ig polypeptides associate to form a Fab.Type: GrantFiled: July 30, 2003Date of Patent: June 26, 2012Assignee: MorphoSys AGInventors: Josef Prassler, Yvonne Stark
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Publication number: 20120129717Abstract: The present disclosure enables collections of variable heavy chain and variable light chain pairs comprising, in part, germline protein sequences that are pre-selected for functional properties relevant to developability, wherein the collections may be used to select against any antigen using, for example, phage display.Type: ApplicationFiled: November 18, 2011Publication date: May 24, 2012Applicant: MORPHOSYS AGInventors: Stefanie Urlinger, Thomas Tiller, Ingrid Schuster, Yvonne Stark
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Publication number: 20100190234Abstract: The present invention relates to methods for the formation of inter-molecular disulphide bonds, including (poly)peptides/proteins, nucleic acids, vectors, host cells and bacteriophages used in these methods. Furthermore the invention relates to the use of this method for the improved display of (poly)peptides/proteins on the surface of bacteriophage particles.Type: ApplicationFiled: August 21, 2008Publication date: July 29, 2010Applicant: MORPHOSYS AGInventors: Josef Prassler, Yvonne Stark
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Publication number: 20060121563Abstract: A tricistronic vector (i.e., a vector capable of expressing three exogenous genet, which are not fused together, under the control of one promoter) effectively can encode an immunoglobulin-presenting polypeptide and two immunoglobulin (Ig) polypeptides. The encoded Ig-presenting polypeptide is able to associate with at least one of the Ig polypeptides via co-expressed associating agents. A vector according to the present invention particularly is suited for phage display technology, e.g., when the Ig-presenting polypeptide is a phage coat protein and the Ig polypeptides associate to form a Fab.Type: ApplicationFiled: July 30, 2003Publication date: June 8, 2006Applicant: Morphosys AGInventors: Josef Prassler, Yvonne Stark