Patents by Inventor Z. Wang

Z. Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7941009
    Abstract: A computerized annotation method achieves real-time operation and better optimization properties while preserving the architectural advantages of the generative modeling approach. A novel clustering algorithm for objects is represented by discrete distributions, or bags of weighted vectors, thereby minimizing the total within cluster distance, a criterion used by the k-means algorithm. A new mixture modeling method, the hypothetical local mapping (HLM) method, is used to efficiently build a probability measure on the space of discrete distributions. Thus, in accord with the invention every image is characterized by a statistical distribution. The profiling model specifies a probability law for distributions directly.
    Type: Grant
    Filed: October 15, 2007
    Date of Patent: May 10, 2011
    Assignee: The Penn State Research Foundation
    Inventors: Jia Li, James Z. Wang
  • Publication number: 20110104228
    Abstract: The invention features the use of a matrix consisting of low molecular weight components for use as a self-eliminating coating for implantable medical devices. The matrix coatings can be used to enhance biocompatibility and to control the local delivery of biologically active agents.
    Type: Application
    Filed: October 17, 2008
    Publication date: May 5, 2011
    Applicant: Interface Biologics, Inc
    Inventors: Roseita Esfand, J. Paul Santerre, Mark J. Ernsting, Vivian Z. Wang, Sylvia Tjahyadi
  • Publication number: 20110103144
    Abstract: A method of trimming FET NVM cells in Multi-Level-Cell (MLC) operation is provided. The method comprises (a) applying a first voltage and a second voltage to a control gate and a bulk of the over-programmed FET NVM cell, respectively; and (b) applying a signal to a drain of the over-programmed FET NVM cell for a time period to produce a limited threshold voltage reduction; wherein polarities of the first voltage and the second voltage are opposite to that of the signal. Thus, the charge placement in the storing material could be precisely controlled within a small range of charge state and produce a multi-bits/cell of higher digital storage density.
    Type: Application
    Filed: November 5, 2009
    Publication date: May 5, 2011
    Inventors: Lee Z. Wang, Jui-Hung Huang
  • Publication number: 20110091508
    Abstract: The invention features oligofluorinated cross-linked polymers and their use in the manufacture of articles and coating surfaces.
    Type: Application
    Filed: October 2, 2008
    Publication date: April 21, 2011
    Applicant: Interface Biologics ,Inc.
    Inventors: Roseita Esfand, J. Paul Santerre, Mark J. Ernsting, H. Hung Pham, Vivian Z. Wang, Meilin Yang
  • Patent number: 7929805
    Abstract: In a system and method for the generation of attack-resistant, user-friendly, image-based CAPTCHAs (Completely Automated Public test to Tell Computers and Humans Apart), controlled distortions are applied to randomly chosen images and presented to a user for annotation from a given list of words. An image is presented that contains multiple connected but independent images with the borders between them distorted or otherwise visually obfuscated in a way that a computer cannot distinguish the borders and a user selects near the center of one of the images. The distortions are performed in a way that satisfies the incongruous requirements of low perceptual degradation and high resistance to attack by content-based image retrieval systems. Word choices are carefully generated to avoid ambiguity as well as to avoid attacks based on the choices themselves.
    Type: Grant
    Filed: January 30, 2007
    Date of Patent: April 19, 2011
    Assignee: The Penn State Research Foundation
    Inventors: James Z. Wang, Ritendra Datta, Jia Li
  • Publication number: 20110034499
    Abstract: The present invention relates to a compound of the following formula: where R1-R6, R10, Y, n, m, p, and q are as defined herein. Compounds and compositions of the present invention are useful for the treatment of diseases associated with the overexpression of CCR2.
    Type: Application
    Filed: June 20, 2008
    Publication date: February 10, 2011
    Inventors: Brian W. Budzik, Hilary Schenck Eidam, Ryan Michael Fox, Krista B. Goodman, Dimitar B. Gotchev, Pamela A. Haile, Terry Vincent Hughes, Ronggang Liu, Nathan A. Miller, Tamara Ann Miskowski, Clark A. Sehon, Andrew Q. Viet, Gren Z. Wang, Jing Zhang
  • Publication number: 20100256130
    Abstract: The present invention relates to morpholinyl, and pyrrolidinyl analogs, pharmaceutical compositions containing them, and their use as antagonists of urotensin II.
    Type: Application
    Filed: May 19, 2010
    Publication date: October 7, 2010
    Inventors: Krista B. Goodman, Michael J. Neeb, Clark A. Sehon, Andrew Q. Viet, Gren Z. Wang
  • Patent number: 7779167
    Abstract: A vehicle audio system 30 reconfigures with a PDAD 32 device by sending a series of queries through a supported channel, preferably a UART channel to the PDAD with the PDAD sending back requested control information 42 and meta-data housing information 46.
    Type: Grant
    Filed: September 28, 2006
    Date of Patent: August 17, 2010
    Assignee: Delphi Technologies, Inc.
    Inventor: Ting Z. Wang
  • Patent number: 7749998
    Abstract: The present invention relates to morpholinyl, and pyrrolidinyl analogs, pharmaceutical compositions containing them, and their use as antagonists of urotensin II.
    Type: Grant
    Filed: July 20, 2007
    Date of Patent: July 6, 2010
    Assignee: GlaxoSmithKline LLC
    Inventors: Krista B. Goodman, Michael J. Neeb, Clark A. Sehon, Andrew Q. Viet, Gren Z. Wang
  • Publication number: 20090275571
    Abstract: The present invention relates to morpholinyl, and pyrrolidinyl analogs, pharmaceutical compositions containing them, and their use as antagonists of urotensin II.
    Type: Application
    Filed: July 20, 2007
    Publication date: November 5, 2009
    Inventors: Krista B. Goodman, Michael J. Neeb, Clark A. Sehon, Andrew Q. Viet, Gren Z. Wang
  • Publication number: 20090204637
    Abstract: A computerized annotation method achieves real-time operation and better optimization properties while preserving the architectural advantages of the generative modeling approach. A novel clustering algorithm for objects is represented by discrete distributions, or bags of weighted vectors, thereby minimizing the total within cluster distance, a criterion used by the k-means algorithm. A new mixture modeling method, the hypothetical local mapping (HLM) method, is used to efficiently build a probability measure on the space of discrete distributions. Thus, in accord with the invention every image is characterized by a statistical distribution. The profiling model specifies a probability law for distributions directly.
    Type: Application
    Filed: October 15, 2007
    Publication date: August 13, 2009
    Applicant: The Penn State Research Foundation
    Inventors: Jia Li, James Z. Wang
  • Patent number: 7539661
    Abstract: Accessed memory locations of a data table are assigned weights based on usage history, and a hash table chains the highest-weight key values to an abbreviated hash index. The hash table includes keys having at least a predetermined weight so that highly accessed keys are identified by hashing. Additionally, the keys chained to a given hash index are ordered based on their weight in order to optimize the overall data retrieval time. The weights assigned to accessed keys are updated over time so that the content of the hash table is adaptively updated to suit the current table look-up requirements.
    Type: Grant
    Filed: June 2, 2005
    Date of Patent: May 26, 2009
    Assignee: Delphi Technologies, Inc.
    Inventor: Ting Z. Wang
  • Publication number: 20090083332
    Abstract: A principled, probabilistic approach to meta-learning acts as a go-between for a ‘black-box’ image annotation system and its users. Inspired by inductive transfer, the approach harnesses available information, including the black-box model's performance, the image representations, and a semantic lexicon ontology. Being computationally ‘lightweight.’ the meta-learner efficiently re-trains over time, to improve and/or adapt to changes. The black-box annotation model is not required to be re-trained, allowing computationally intensive algorithms to be used. Both batch and online annotation settings are accommodated. A “tagging over time” approach produces progressively better annotation, significantly outperforming the black-box as well as the static form of the meta-learner, on real-world data.
    Type: Application
    Filed: September 19, 2008
    Publication date: March 26, 2009
    Applicant: The Penn State Research Foundation
    Inventors: Ritendra Datta, Dhiraj Joshi, Jia Li, James Z. Wang
  • Publication number: 20080285860
    Abstract: The aesthetic quality of a picture is automatically inferred using visual content as a machine learning problem using, for example, a peer-rated, on-line photo sharing Website as data source. Certain visual features of images are extracted based on the intuition that they can discriminate between aesthetically pleasing and displeasing images. A one-dimensional support vector machine is used to identify features that have noticeable correlation with the community-based aesthetics ratings. Automated classifiers are constructed using the support vector machines and classification trees, with a simple feature selection heuristic being applied to eliminate irrelevant features. Linear regression on polynomial terms of the features is also applied to infer numerical aesthetics ratings.
    Type: Application
    Filed: May 7, 2008
    Publication date: November 20, 2008
    Applicant: The Penn State Research Foundation
    Inventors: Ritendra Datta, Jia Li, James Z. Wang
  • Patent number: 7432258
    Abstract: The present invention relates to 4?-[(1R)-1-[[(6,7-dichloro-3-oxo-2,3-dihydro-4H-1,4-benzoxazin- 4-yl)acetyl](methyl)amino]-2-(4-morpholinyl)ethyl]-4-biphenylcarboxylic acid and its pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their use as antagonists of urotensin II.
    Type: Grant
    Filed: July 20, 2007
    Date of Patent: October 7, 2008
    Assignee: SmithKline Beecham Corporation
    Inventors: Krista B. Goodman, Michael J. Neeb, Clark A. Sehon, Andrew Q. Viet, Gren Z. Wang
  • Publication number: 20080154400
    Abstract: A vehicle audio system 30 reconfigures with a PDAD 32 device by sending a series of queries through a supported channel, preferably a UART channel to the PDAD with the PDAD sending back requested control information 42 and meta-data housing information 46.
    Type: Application
    Filed: September 28, 2006
    Publication date: June 26, 2008
    Inventor: Ting Z. Wang
  • Publication number: 20080125427
    Abstract: Novel inhibitors of Rho-kinases are disclosed.
    Type: Application
    Filed: June 17, 2005
    Publication date: May 29, 2008
    Applicant: SMITHKLINE BEECHAM CORPORATION
    Inventors: Clark A. Sehon, Dennis Lee, Krista B. Goodman, Gren Z. Wang, Andrew Q. Viet
  • Publication number: 20080021023
    Abstract: The present invention relates to morpholinyl, and pyrrolidinyl analogs, pharmaceutical compositions containing them, and their use as antagonists of urotensin II.
    Type: Application
    Filed: July 20, 2007
    Publication date: January 24, 2008
    Inventors: Krista B. Goodman, Michael J. Neeb, Clark A. Sehon, Andrew Q. Viet, Gren Z. Wang
  • Patent number: 7205318
    Abstract: The present application describes lactam-containing cyclic diamines and derivatives thereof of Formula I: P4-M-M4I or pharmaceutically acceptable salt forms thereof, wherein M is a non-aromatic carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.
    Type: Grant
    Filed: March 16, 2004
    Date of Patent: April 17, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jennifer X. Qiao, Tammy C. Wang, Gren Z. Wang, Timur Gungor
  • Publication number: 20070014377
    Abstract: Pilot data and data-bearer data are formed to be mutually orthogonal and in each other's null-space. Data to be transmitted is first modulated with the data-bearer matrix and then pilot data is added thereto. The pilot data may be added to each modulated symbol, thereby increasing significantly the density of pilot information available at the receiver for channel state estimation. When pilot data is added across an entire transmitted block of data, data detection performance is improved for even fast fading Rayleigh fading channels.
    Type: Application
    Filed: June 21, 2006
    Publication date: January 18, 2007
    Inventors: Chaiyod Pirak, Z. Wang, K.J. Liu