Patents by Inventor Zaïne El Abiddine Robert MAMOUN

Zaïne El Abiddine Robert MAMOUN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EXTRACELLULAR VESICLES HARBORING A SPIKE PROTEIN, NUCLEIC ACIDS FOR PRODUCING THE SAME, AND METHOD OF IMMUNIZING A SUBJECT AGAINST SARS-CoV-2 USING THE SAME
    Publication number: 20220096624
    Abstract: A nucleic acid including (i) a sequence of a S gene coding for a Spike protein and (ii) a sequence coding for a pilot peptide which interacts with ESCRT proteins. Also, extracellular vesicles, in particular exosomes, harboring at their external surface a Spike protein, obtainable by transfecting cells with the nucleic acid. Further, a method of immunizing a subject against a virus of the Orthocoronavirinae subfamily, in particular against SARS-CoV-2, by DNA prime-protein boost using the nucleic acid and the extracellular vesicles of the invention.
    Type: Application
    Filed: September 29, 2020
    Publication date: March 31, 2022
    Applicant: CILOA
    Inventors: Bernadette Nadine TRENTIN, Katarzyna POLAK, Zaïne El Abiddine Robert MAMOUN