Patents by Inventor Zabar Sasson

Zabar Sasson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bis-2-furanidyl ether and method of preparation
    Patent number: 4212814
    Abstract: The present invention relates to a new process for the preparation of N.sup.1 -(2'-furanidyl)-5-fluoro-uracil, also called Ftorafur, which is a very important anti-cancer compound. Said process comprises reacting 2,3-dihydrofuran with water in the presence of a catalytic amount of an acidic catalyst at a pH below 2.5, removing excess of unreacted starting materials and reacting the mixture obtained with silylated-5-fluoro-uracil is in the presence of a Friedel Crafts type catalyst uracil in an inert organic solvent. The new process has many advantages in comparison with those used so far.
    Type: Grant
    Filed: April 30, 1979
    Date of Patent: July 15, 1980
    Assignee: Abic, Ltd.
    Inventors: Eva Schonberger, Zabar Sasson, Uri Michael
  • Process for the preparation of N.sup.1 -(2'-furanidyl)-5-fluoro-uracil
    Patent number: 4174446
    Abstract: The present invention relates to a new process for the preparation of N.sup.1 -(2'-furanidyl)-5-fluoro-uracil, also called Ftorafur, which is a very important anti-cancer compound. Said process comprises reacting 2,3-dihydrofuran with water in the presence of a catalytic amount of an acidic catalyst at a pH below 2.5, removing excess of unreacted starting materials and reacting the mixture obtained with silylated-5-fluoro-uracil is in the presence of a Friedel Crafts type catalyst uracil in an inert organic solvent. The new process has many advantages in comparison with those used so far.
    Type: Grant
    Filed: October 11, 1977
    Date of Patent: November 13, 1979
    Assignee: ABIC Ltd.
    Inventors: Eva Schonberger, Zabar Sasson, Uri Michael