Patents by Inventor Zachary A. Bornholdt

Zachary A. Bornholdt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MONOCLONAL ANTIBODIES AND COCKTAILS FOR TREATMENT OF EBOLA INFECTIONS
    Publication number: 20230044044
    Abstract: Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
    Type: Application
    Filed: July 1, 2022
    Publication date: February 9, 2023
    Inventors: Zachary A. Bornholdt, Larry Zeitlin, Kartik Chandran, Anna Wec, Laura Walker
  • ANTI-CRIMEAN-CONGO HEMORRHAGIC FEVER VIRUS ANTIBODIES, AND METHODS OF THEIR GENERATION AND USE
    Publication number: 20230000979
    Abstract: Anti-CCHFV antibodies with neutralizing potency and protective efficacy against CCHFV are provided, as well as methods for their identification, isolation, generation, and methods for their preparation and use are provided.
    Type: Application
    Filed: May 31, 2022
    Publication date: January 5, 2023
    Inventors: Zachary A. Bornholdt, Akaash Mishra, Laura M. Walker, Noel T. Pauli, Daniel Maurer, Kartik Chandran, Jens Maximilian Fels, Dafna Abelson, Jason Scott McLellan, Jonathan R. Lai, Ariel Wirchnianski, Olivia Vergnolle, John M. Dye, Andrew S. Herbert
  • Monoclonal antibodies and cocktails for treatment of Ebola infections
    Patent number: 11407817
    Abstract: Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
    Type: Grant
    Filed: June 9, 2020
    Date of Patent: August 9, 2022
    Assignees: MAPP BIOPHARMACEUTICAL, INC., ALBERT EINSTEIN COLLEGE OF MEDICINE, ADIMAB, LLC
    Inventors: Zachary A. Bornholdt, Larry Zeitlin, Kartik Chandran, Anna Z. Wec, Laura Walker
  • Monoclonal antibodies and cocktails for treatment of Ebola infections
    Patent number: 11407816
    Abstract: Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially, similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
    Type: Grant
    Filed: June 9, 2020
    Date of Patent: August 9, 2022
    Assignees: MAPP BIOPHARMACEUTICAL, INC., ALBERT EINSTEIN COLLEGE OF MEDICINE, ADIMAB, LLC
    Inventors: Zachary A. Bornholdt, Larry Zeitlin, Kartik Chandran, Anna Wec, Laura Walker
  • Monoclonal antibodies and cocktails for treatment of Ebola infections
    Patent number: 11254732
    Abstract: Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
    Type: Grant
    Filed: June 9, 2020
    Date of Patent: February 22, 2022
    Assignees: MAPP BIOPHARMACEUTICAL, INC., ALBERT EINSTEIN COLLEGE OF MEDICINE, ADIMAB, LLC
    Inventors: Zachary A. Bornholdt, Larry Zeitlin, Kartik Chandran, Anna Wec, Laura Walker
  • Monoclonal antibodies and cocktails for treatment of Ebola infections
    Patent number: 11242379
    Abstract: Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
    Type: Grant
    Filed: June 9, 2020
    Date of Patent: February 8, 2022
    Assignees: MAPP BIOPHARMACEUTICAL, INC., ALBERT EINSTEIN COLLEGE OF MEDICINE, ADIMAB, LLC
    Inventors: Zachary A. Bornholdt, Larry Zeitlin, Kartik Chandran, Anna Wec, Laura Walker
  • Monoclonal antibodies and cocktails for treatment of Ebola infections
    Patent number: 11242378
    Abstract: Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially, similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
    Type: Grant
    Filed: June 9, 2020
    Date of Patent: February 8, 2022
    Assignees: MAPP BIOPHARMACEUTICAL, INC., ALBERT EINSTEIN COLLEGE OF MEDICINE, ADIMAB, LLC
    Inventors: Zachary A. Bornholdt, Larry Zeitlin, Kartik Chandran, Anna Wec, Laura Walker
  • ANTI-CRIMEAN-CONGO HEMORRHAGIC FEVER VIRUS ANTIBODIES, AND METHODS OF THEIR GENERATION AND USE
    Publication number: 20210355195
    Abstract: Anti-CCHFV antibodies with neutralizing potency and protective efficacy against CCHFV are provided, as well as methods for their identification, isolation, generation, and methods for their preparation and use are provided.
    Type: Application
    Filed: May 5, 2021
    Publication date: November 18, 2021
    Inventors: Zachary A. Bornholdt, Akaash Mishra, Laura M. Walker, Noel T. Pauli, Daniel Maurer, Kartik Chandran, Jens Maximilian Fels, Dafna Abelson, Jason Scott McLellan, Jonathan R. Lai, Ariel Wirchnianski, Olivia Vergnolle
  • Monoclonal antibodies and cocktails for treatment of ebola infections
    Patent number: 10836810
    Abstract: Described herein are compositions and methods for the prevention and treatment of ebolavirus infection certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
    Type: Grant
    Filed: February 17, 2018
    Date of Patent: November 17, 2020
    Assignees: MAPP BIOPHARMACEUTICAL, INC., ALBERT EINSTEIN COLLEGE OF MEDICINE, ADIMAB, LLC
    Inventors: Zachary A. Bornholdt, Larry Zeitlin, Kartik Chandran, Anna Wec, Laura Walker
  • MONOCLONAL ANTIBODIES AND COCKTAILS FOR TREATMENT OF EBOLA INFECTIONS
    Publication number: 20200354437
    Abstract: Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially, similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
    Type: Application
    Filed: June 9, 2020
    Publication date: November 12, 2020
    Inventors: Zachary A. Bornholdt, Larry Zeitlin, Kartik Chandran, Anna Wec, Laura Walker
  • MONOCLONAL ANTIBODIES AND COCKTAILS FOR TREATMENT OF EBOLA INFECTIONS
    Publication number: 20200354438
    Abstract: Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
    Type: Application
    Filed: June 9, 2020
    Publication date: November 12, 2020
    Inventors: Zachary A. Bornholdt, Larry Zeitlin, Kartik Chandran, Anna Wec, Laura Walker
  • MONOCLONAL ANTIBODIES AND COCKTAILS FOR TREATMENT OF EBOLA INFECTIONS
    Publication number: 20200299363
    Abstract: Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
    Type: Application
    Filed: June 9, 2020
    Publication date: September 24, 2020
    Inventors: Zachary A. Bornholdt, Larry Zeitlin, Kartik Chandran, Anna Wec, Laura Walker
  • MONOCLONAL ANTIBODIES AND COCKTAILS FOR TREATMENT OF EBOLA INFECTIONS
    Publication number: 20200299361
    Abstract: Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
    Type: Application
    Filed: June 9, 2020
    Publication date: September 24, 2020
    Inventors: Zachary A. Bornholdt, Larry Zeitlin, Kartik Chandran, Anna Wec, Laura Walker
  • MONOCLONAL ANTIBODIES AND COCKTAILS FOR TREATMENT OF EBOLA INFECTIONS
    Publication number: 20200299362
    Abstract: Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially, similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
    Type: Application
    Filed: June 9, 2020
    Publication date: September 24, 2020
    Inventors: Zachary A. Bornholdt, Larry Zeitlin, Kartik Chandran, Anna Wec, Laura Walker
  • MONOCLONAL ANTIBODIES AND COCKTAILS FOR TREATMENT OF EBOLA INFECTIONS
    Publication number: 20180244758
    Abstract: Described herein are compositions and methods for the prevention and treatment of ebolavirus infection certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
    Type: Application
    Filed: February 17, 2018
    Publication date: August 30, 2018
    Inventors: Zachary A. Bornholdt, Larry Zeitlin, Kartik Chandran, Anna Wec, Laura Walker