Abstract: Various implementations include a method of applying a surgery reference marker to skin of a patient. The method includes providing a medical scanner having at least one positioning laser; disposing the patient in a desired position relative to the medical scanner such that the at least one positioning laser illuminates a portion of the skin of the patient; disposing a temporary tattoo on the portion of the skin of the patient, the temporary tattoo having at least one positioning indicator configured to be applied to the skin of the patient, wherein the temporary tattoo is disposed such that the at least one positioning indicator indicates a position of the at least one positioning laser; and applying the temporary tattoo such that the at least one positioning indicator is transferred to the skin of the patient.