Abstract: The systems, devices and methods can deliver a therapeutic material within a cavity of a joint while preventing leakage into the joint space. The systems may include a delivery device configured to deliver a therapeutic material to a treatment area within a bone cavity of a bone. The device may include a containment device. The containment device may include a body having a first end, a second, and a length there between, and an expandable member disposed at the first end of the body so as to cover the first end. The expandable member may be configured to move between an expanded state and a collapsed state. The system may further include an access device that includes a first channel and a second channel. The first channel may be configured to receive the expandable containment device and the second channel may be configured to receive the delivery device.