Patents by Inventor Zachary D. HORNBY

Zachary D. HORNBY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REPLICATION STRESS PATHWAY AGENT COMPOSITIONS AND METHODS FOR TREATING CANCER
    Publication number: 20230272485
    Abstract: Provided herein are methods of treating cancer in a subject, wherein the cancer is extrachromosomal DNA-positive (ecDNA-positive) or therapeutically resistant, the method comprising administering to the subject a therapeutically effective amount of a replication stress (RS) pathway agent alone or in combination with a targeted therapeutic.
    Type: Application
    Filed: February 15, 2023
    Publication date: August 31, 2023
    Inventors: Christian HASSIG, Ryan HANSEN, Snezana MILUTINOVIC, Zachary D. HORNBY, Sudhir CHOWDHRY, Kristen TURNER, Deepti WILKINSON, Shailaja KASIBHATLA
  • REPLICATION STRESS PATHWAY AGENT COMPOSITIONS AND METHODS FOR TREATING CANCER
    Publication number: 20230248728
    Abstract: Provided herein are methods of treating cancer in a subject, wherein the cancer is extrachromosomal DNA-positive (ecDNA-positive) or therapeutically resistant, the method comprising administering to the subject a therapeutically effective amount of a replication stress (RS) pathway agent alone or in combination with a targeted therapeutic.
    Type: Application
    Filed: March 24, 2023
    Publication date: August 10, 2023
    Inventors: Christian HASSIG, Ryan HANSEN, Snezana MILUTINOVIC, Jason CHRISTIANSEN, Zachary D. HORNBY, Sudhir CHOWDHRY, Anthony CELESTE, Kristen TURNER, Deepti WILKINSON
  • COMBINATIONS FOR THE TREATMENT OF CANCER
    Publication number: 20210113555
    Abstract: Described herein are combinations comprising a therapeutically effective amount of a first agent and a therapeutically effective amount of a second agent, wherein the first agent is an inhibitor of ALK, ROS1, TrkA, TrkB, or TrkC activity, or a combination thereof, and methods of using such combinations in the treatment of patients having cancer.
    Type: Application
    Filed: December 9, 2020
    Publication date: April 22, 2021
    Applicant: IGNYTA, INC.
    Inventors: Gang Li, Ge Wei, Zachary D. Hornby, Jonathan Ee-ren Lim
  • Combinations for the treatment of cancer
    Patent number: 10869864
    Abstract: Described herein are combinations comprising a therapeutically effective amount of a first agent and a therapeutically effective amount of a second agent, wherein the first agent is an inhibitor of ALK, ROS1, TrkA, TrkB, or TrkC activity, or a combination thereof, and methods of using such combinations in the treatment of patients having cancer.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: December 22, 2020
    Assignee: IGNYTA, INC.
    Inventors: Gang Li, Ge Wei, Zachary D. Hornby, Jonathan Ee-ren Lim
  • COMBINATIONS FOR THE TREATMENT OF CANCER
    Publication number: 20190000840
    Abstract: Described herein are combinations comprising a therapeutically effective amount of a first agent and a therapeutically effective amount of a second agent, wherein the first agent is an inhibitor of ALK, ROS1, TrkA, TrkB, or TrkC activity, or a combination thereof, and methods of using such combinations in the treatment of patients having cancer.
    Type: Application
    Filed: December 15, 2016
    Publication date: January 3, 2019
    Applicant: IGNYTA, INC.
    Inventors: Gang LI, Ge WEI, Zachary D. HORNBY, Jonathan Ee-ren LIM