Abstract: Disclosed herein, in certain embodiments, are recombinant PNMA2 and endogenous Gag polypeptides, capsids comprising the recombinant PNMA2 or endogenous Gag polypeptides, and methods of making and using recombinant PNMA2 and endogenous Gag polypeptides.

Abstract: Disclosed herein, in certain embodiments, are recombinant Arc and endogenous Gag polypeptides, and methods of using recombinant Arc and endogenous Gag polypeptides.

Abstract: Described herein is a composition comprising: 1) an ARC polypeptide or an endogenous gag (endo-gag) polypeptide; 2) a pathogen-associated antigen; and 3) an adjuvant. Also described herein are vaccines and methods of vaccination using compositions comprising: 1) an ARC polypeptide or an endogenous gag (endo-gag) polypeptide; 2) a pathogen-associated antigen; and 3) an adjuvant.

Abstract: Disclosed herein, in certain embodiments, are recombinant Arc and endogenous Gag polypeptides, and methods of using recombinant Arc and endogenous Gag polypeptides.

Abstract: Nucleic acids encoding endogenous Gag peptides can be isolated from various organisms. Nucleic acids encoding various endogenous Gag polypeptides can be isolated from human DNA. The nucleic acids can be used to express endogenous Gag polypeptides that can be assembled into capsids. Endogenous Gag polypeptides and capsids can be used package cargo and/or deliver it to cells, for example, to package and/or deliver a nucleic acid molecule for use in gene editing, such as a component involved in a CRISPR-Cas system.

Abstract: Disclosed herein, in certain embodiments, are recombinant Arc and endogenous Gag polypeptides, and methods of using recombinant Arc and endogenous Gag polypeptides.

Abstract: Disclosed herein, in certain embodiments, are recombinant Arc and endogenous Gag polypeptides, and methods of using recombinant Arc and endogenous Gag polypeptides.

Abstract: Disclosed herein, in certain embodiments, are recombinant Arc and endogenous Gag polypeptides, and methods of using recombinant Arc and endogenous Gag polypeptides.

Abstract: Disclosed herein, in certain embodiments, are recombinant Arc and endogenous Gag polypeptides, and methods of using recombinant Arc and endogenous Gag polypeptides.

Abstract: Disclosed herein, in certain embodiments, are recombinant Arc and endogenous Gag polypeptides, and methods of using recombinant Arc and endogenous Gag polypeptides.

Abstract: Described herein is a composition comprising: 1) an ARC polypeptide or an endogenous gag (endo-gag) polypeptide; 2) a pathogen-associated antigen; and 3) an adjuvant. Also described herein are vaccines and methods of vaccination using compositions comprising: 1) an ARC polypeptide or an endogenous gag (endo-gag) polypeptide; 2) a pathogen-associated antigen; and 3) an adjuvant.

Abstract: A locking gun storage container with a main box, a biased lid mounted on one end of the main box, and a lock mechanism that selectively locks the lid in a closed position. Inside the interior cavity of the main box is a holster with an interior pocket configured to hold a handgun. The holster includes an upper edge attached to a first hinge assembly mounted to the inside surface of the lid and a lower edge attached to a second hinge assembly attached to the inside surface of the main box. The two hinge assemblies are configured to hold and support the holster when holding a handgun upright over the interior cavity of the main box when the lid is opened and then repositioned the holster inside the interior cavity when the lid is closed. Mounted on the main box a coupler that selectively attaches to an external mount.

Abstract: A locking gun storage container that includes a main box, an upward biased lid pivotally mounted on one end of the main box, and a lock mechanism that allows the user to lock the lid in a closed position over the main box. Mounted inside the interior cavity of the main box is a holster with an interior pocket configured to hold a hand gun. The holster includes a front edge attached to a first hinge mounted to the inside surface of the lid and a rear edge attached to a second hinge assembly attached to the inside surface of the main box. The two hinge assemblies are configured to hold the holster vertically upright inside the interior cavity when the lid is opened and then repositioned to hold the holster horizontally inside the interior cavity when the lid is closed. Mounted on the bottom surface of the main box is a coupler that selectively attaches to a mount attached to a mounting surface enabling the enclosure to be selectively attached or detached to the mounting surface.