Abstract: A portable grill adapted to be supported by a hitch of a vehicle is provided so that the portable grill is disposed outside the vehicle during use and transportation so as to not take up important storage space in the transporting vehicle. The portable grill may include a body pivotally connected to a cooperating lid so as to define a grilling space. The components of the portable grill may be made of 10 gauge steel metal and rigidly interconnected by welds to provide sufficient operable durability. Specifically, the body may provide a rigidly connected lower frame assembly having a hitch tube dimensioned and adapted to securely mount the body to the hitch of vehicle during transport and use.

Abstract: The present invention provides novel PI3-Kinase antagonists and methods of use thereof.

Abstract: The present invention provides novel compounds that are antagonists of PI3 kinase, PI3 kinase and tryosine kinase, PI3Kinase and mTOR, or PI3Kinase, mTOR and tryosine kinase.

Abstract: The invention provides a method for mapping the location of the post-translational modifications of a post-translationally modified peptide. Also provided is a solid-phase support that includes a reagent for modifying a post-translationally modified amino acid residues of a post-translationally modified, converting it into a substrate for a peptidase.

Abstract: The present invention provides novel endonucleases that site-specifically cleave a post-translationally modified polypeptide at a site of post-translational modification. The present invention further provides methods making and using the endonucleases, including methods of mapping post-translational modifications in the human genome.