Patents by Inventor Zachary Novakovic

Zachary Novakovic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Myristoylated leptin-related peptides and uses thereof
    Patent number: 10195254
    Abstract: A pharmaceutical compound for the treatment of obesity related disorder that is a conjugate of myristic acid and a leptin-related peptide. Preferably, the leptin-related peptide is OB3 that has been D-substituted at Leu-4. The resulting conjugate significantly improved the pharmacokinetic profile of the leptin-related peptide by extending its half-life from less than one hour to as long as twenty-eight hours, depending on the route of delivery, increasing uptake, reducing the rate of plasma clearance, and enabling the minimal effective dose to be reduced several fold.
    Type: Grant
    Filed: August 11, 2015
    Date of Patent: February 5, 2019
    Assignee: ALBANY MEDICAL COLLEGE
    Inventors: Patricia Grasso, Zachary Novakovic
  • MYRISTOYLATED LEPTIN-RELATED PEPTIDES AND USES THEREOF
    Publication number: 20170312340
    Abstract: A pharmaceutical compound for the treatment of obesity related disorder that is a conjugate of myristic acid and a leptin-related peptide. Preferably, the leptin-related peptide is OB3 that has been D-substituted at Leu-4. The resulting conjugate significantly improved the pharmacokinetic profile of the leptin-related peptide by extending its half-life from less than one hour to as long as twenty-eight hours, depending on the route of delivery, increasing uptake, reducing the rate of plasma clearance, and enabling the minimal effective dose to be reduced several fold.
    Type: Application
    Filed: August 11, 2015
    Publication date: November 2, 2017
    Applicant: ALBANY MEDICAL COLLEGE
    Inventors: Patricia Grasso, Zachary Novakovic