Patents by Inventor Zachery KARTJE

Zachery KARTJE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tuning CRISPR/Cas9 activity with chemically modified nucleotide substitutions
    Patent number: 11306305
    Abstract: The present disclosure provides CRISPR/Cas9 ribonucleoprotein compositions comprising chemically modified CRISPR RNA (crRNA) guide and trans-acting CRISPR RNA (tracrRNA) components. Methods of using the disclosed CRISPR/Cas9 ribonucleoprotein compositions are also provided.
    Type: Grant
    Filed: September 22, 2017
    Date of Patent: April 19, 2022
    Assignees: Board of Trustees of Southern Illinois University
    Inventors: Keith Gagnon, Masad Damha, Elise Malek-Adamian, Maryam Habibian, Daniel Timothy O'Reilly, Zachery Kartje
  • Tuning CRISPR/CAS9 Activity with Chemically Modified Nucleotide Substitutions
    Publication number: 20190185844
    Abstract: The present disclosure provides CRISPR/Cas9 ribonucleoprotein compositions comprising chemically modified CRISPR RNA (crRNA) guide and trans-acting CRISPR RNA (tracrRNA) components. Methods of using the disclosed CRISPR/Cas9 ribonucleoprotein compositions are also provided.
    Type: Application
    Filed: September 22, 2017
    Publication date: June 20, 2019
    Applicants: Board of Trustees of Southern lllinois University, The Royal Institution for the Advancement of Learning/McGill University
    Inventors: Keith GAGNON, Masad DAMHA, Elise MALEK-ADAMIAN, Maryam HABIBIAN, Daniel O'REILLY, Zachery KARTJE