Patents by Inventor Zahoor A. Shah

Zahoor A. Shah has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Development of a cofilin inhibitor for the treatment of hemorrhagic brain injury-induced neuroinflammation
    Patent number: 11548850
    Abstract: Compounds and methods for inhibiting cofilin activity or reducing total cofilin, improving motor deficits, attenuating LPS-induced microglial activation and inflammation, reducing microglial migration and proliferation, reducing TNF-?, reducing NF-?B, and improving motor deficits in a subject are described.
    Type: Grant
    Filed: May 5, 2020
    Date of Patent: January 10, 2023
    Assignee: The University of Toledo
    Inventors: Saleh Alaqel, Viranga Tillekeratne, Zahoor A. Shah
  • Furoxans as therapies for neurodegenerative disorders
    Patent number: 10913732
    Abstract: Furoxan compounds, compositions comprising the same, and methods of making and using the same, are described.
    Type: Grant
    Filed: January 28, 2020
    Date of Patent: February 9, 2021
    Assignee: The University of Toledo
    Inventors: Isaac Schiefer, Zahoor Shah
  • Development of a Cofilin Inhibitor for the Treatment of Hemorrhagic Brain Injury-Induced Neuroinflammation
    Publication number: 20200369603
    Abstract: Compounds and methods for inhibiting cofilin activity or reducing total cofilin, improving motor deficits, attenuating LPS-induced microglial activation and inflammation, reducing microglial migration and proliferation, reducing TNF-?, reducing NF-?B, and improving motor deficits in a subject are described.
    Type: Application
    Filed: May 5, 2020
    Publication date: November 26, 2020
    Applicant: The University of Toledo
    Inventors: Saleh Alaqel, Viranga Tillekeratne, Zahoor A. Shah
  • Reactive oxygen species-sensitive nitric oxide synthase inhibitors for the treatment of ischemic stroke
    Patent number: 10829441
    Abstract: Disclosed are ROS-sensitive NOS inhibitors, as well as methods of making and using the same.
    Type: Grant
    Filed: October 31, 2018
    Date of Patent: November 10, 2020
    Assignee: The University of Toledo
    Inventors: Kevin M. Nash, Isaac Schiefer, Zahoor Shah
  • FUROXANS AS THERAPIES FOR NEURODEGENERATIVE DISORDERS
    Publication number: 20200172526
    Abstract: Furoxan compounds, compositions comprising the same, and methods of making and using the same, are described.
    Type: Application
    Filed: January 28, 2020
    Publication date: June 4, 2020
    Applicant: The University of Toledo
    Inventors: Isaac Schiefer, Zahoor Shah
  • Furoxans as therapies for neurodegenerative disorders
    Patent number: 10590119
    Abstract: Furoxan compounds, compositions comprising the same, and methods of making and using the same, are described.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: March 17, 2020
    Assignee: The University of Toledo
    Inventors: Isaac Schiefer, Zahoor Shah
  • FUROXANS AS THERAPIES FOR NEURODEGENERATIVE DISORDERS
    Publication number: 20190308959
    Abstract: Furoxan compounds, compositions comprising the same, and methods of making and using the same, are described.
    Type: Application
    Filed: November 14, 2017
    Publication date: October 10, 2019
    Applicant: The University of Toledo
    Inventors: Isaac Schiefer, Zahoor Shah
  • Reactive Oxygen Species-Sensitive Nitric Oxide Synthase Inhibitors for the Treatment of Ischemic Stroke
    Publication number: 20190144377
    Abstract: Disclosed are ROS-sensitive NOS inhibitors, as well as methods of making and using the same.
    Type: Application
    Filed: October 31, 2018
    Publication date: May 16, 2019
    Applicant: The University of Toledo
    Inventors: Kevin M. Nash, Isaac Schiefer, Zahoor Shah