Patents by Inventor Zaihong Zhang

Zaihong Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11313790
    Abstract: A method for detecting concentration of iodine in water samples. An arsenite-containing test solution, a tetravalent cerium ion-containing test solution and a series of iodine-containing standard solutions are prepared. The standard solutions are added to primary wells of a microplate, respectively. A water sample is added to a secondary well. The arsenite-containing test solution and the tetravalent cerium ion-containing test solution are sequentially added to the primary wells and the secondary well. Reaction mixture in each well is reacted and then measured for absorbance by a detector. A standard curve is plotted according to the absorbance of each primary well and a concentration of each iodine-containing standard solution. The absorbance of the sample is plugged into the standard curve to obtain an iodine concentration in the sample.
    Type: Grant
    Filed: August 26, 2020
    Date of Patent: April 26, 2022
    Assignee: Harbin Medical University
    Inventors: Xiaohong Ji, Yanhui Gao, Yanmei Yang, Dianjun Sun, Liaowei Wu, Chenlu Fan, Qun Lou, Mengyao Su, Xin Zhang, Zaihong Zhang
  • Publication number: 20210181097
    Abstract: A method for detecting concentration of iodine in water samples. An arsenite-containing test solution, a tetravalent cerium ion-containing test solution and a series of iodine-containing standard solutions are prepared. The standard solutions are added to primary wells of a microplate, respectively. A water sample is added to a secondary well. The arsenite-containing test solution and the tetravalent cerium ion-containing test solution are sequentially added to the primary wells and the secondary well. Reaction mixture in each well is reacted and then measured for absorbance by a detector. A standard curve is plotted according to the absorbance of each primary well and a concentration of each iodine-containing standard solution. The absorbance of the sample is plugged into the standard curve to obtain an iodine concentration in the sample.
    Type: Application
    Filed: August 26, 2020
    Publication date: June 17, 2021
    Inventors: Xiaohong JI, Yanhui GAO, Yanmei YANG, Dianjun SUN, Liaowei WU, Chenlu FAN, Qun LOU, Mengyao SU, Xin ZHANG, Zaihong ZHANG
  • Patent number: 9834563
    Abstract: The present invention relates to a compound represented by formula (I): and pharmaceutically acceptable salts thereof. The compounds of formula I are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.
    Type: Grant
    Filed: December 17, 2014
    Date of Patent: December 5, 2017
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: William K. Hagmann, Bing Li, Jason W. Szewczyk, Bowei Wang, Dann Parker, Timothy Blizzard, Hubert Josien, Purakkattle Biju, Harry Chobanian, Candido Gude, Ravi P. Nargund, Barbara Pio, Qun Dang, Linus S. Lin, Bin Hu, Mingxiang Cui, Zhengxia Chen, Meibi Dai, Zaihong Zhang, Ying Lv, Lili Tian
  • Publication number: 20170166578
    Abstract: The present invention relates to a compound represented by formula (I): and pharmaceutically acceptable salts thereof. The compounds of formula I are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.
    Type: Application
    Filed: December 17, 2014
    Publication date: June 15, 2017
    Inventors: William K. Hagmann, Bing Li, Jason W. Szewczyk, Bowei Wang, Dann Parker, Timothy Blizzard, Hubert Josien, Purakkattle Biju, Harry Chobanian, Candido Gude, Ravi P. Nargund, Barbara Pio, Qun Dang, Linus S. Lin, Bin Hu, Mingxiang Cui, Zhengxia Chen, Meibi Dai, Zaihong Zhang, Ying Lv, Lili Tian