Patents by Inventor Zailu LI

Zailu LI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for enhancing vanillin resistance of by knocking out SNG1 gene
    Patent number: 11999957
    Abstract: A method of enhancing vanillin resistance of Saccharomyces cerevisiae, including: knocking out SNG1 gene from a genome of Saccharomyces cerevisiae. This application further provides a mutant of SNG1 gene of Saccharomyces cerevisiae including the nucleotide sequence shown in SEQ ID NO: 1, where the sequence shown in SEQ ID NO: 1, from left to right, consists of a ?18˜+203 bp fragment of SNG1 gene of Saccharomyces cerevisiae, a nucleotide fragment of loxp-KanMX4-loxp and a +1446˜+1644 bp fragment of the SNG1 gene of Saccharomyces cerevisiae.
    Type: Grant
    Filed: December 10, 2020
    Date of Patent: June 4, 2024
    Assignee: QILU UNIVERSITY OF TECHNOLOGY
    Inventors: Xiaoming Bao, Liyun Song, Xinning Wang, Wenyan Cao, Weiquan Zhao, Zailu Li
  • C6/C5 co-fermented capable of relieving antagonism between high xylose utilization and high robustness and application thereof
    Patent number: 11359177
    Abstract: The present invention further discloses an application of Saccharomyces cerevisiae in the fermentation of a second generation fuel, ethanol, with a straw lignocellulose biomass hydrolysate as a raw material. Experiments prove that the strain of the prevent invention has an efficient co-fermentation capacity of C6/C5 while tolerating multiple inhibitors, and can consume all the glucose and xylose to produce ethanol; and the sugar-alcohol conversion rate is up to 0.43 g g?1. The strain and screening strategy used in the present invention provide technical reference and basis for the further breeding of a Saccharomyces cerevisiae strain which has a superior fermenting property and is produced by the second generation fuel, ethanol.
    Type: Grant
    Filed: August 13, 2021
    Date of Patent: June 14, 2022
    Assignee: QILU UNIVERSITY OF TECHNOLOGY
    Inventors: Xiaoming Bao, Jianzhi Zhao, Fangqing Wei, Hongxing Li, Zailu Li
  • C6/C5 CO-FERMENTED SACCHAROMYCES CEREVISIAE CAPABLE OF RELIEVING ANTAGONISM BETWEEN HIGH XYLOSE UTILIZATION AND HIGH ROBUSTNESS AND APPLICATION THEREOF
    Publication number: 20220154131
    Abstract: The present invention further discloses an application of Saccharomyces cerevisiae in the fermentation of a second generation fuel, ethanol, with a straw lignocellulose biomass hydrolysate as a raw material. Experiments prove that the strain of the prevent invention has an efficient co-fermentation capacity of C6/C5 while tolerating multiple inhibitors, and can consume all the glucose and xylose to produce ethanol; and the sugar-alcohol conversion rate is up to 0.43 g g?1. The strain and screening strategy used in the present invention provide technical reference and basis for the further breeding of a Saccharomyces cerevisiae strain which has a superior fermenting property and is produced by the second generation fuel, ethanol.
    Type: Application
    Filed: August 13, 2021
    Publication date: May 19, 2022
    Inventors: Xiaoming BAO, Jianzhi ZHAO, Fangqing WEI, Hongxing LI, Zailu LI
  • METHOD FOR ENHANCING VANILLIN RESISTANCE OF SACCHAROMYCES CEREVISIAE BY KNOCKING OUT SNG1 GENE
    Publication number: 20210388365
    Abstract: A method of enhancing vanillin resistance of Saccharomyces cerevisiae, including: knocking out SNG1 gene from a genome of Saccharomyces cerevisiae. This application further provides a mutant of SNG1 gene of Saccharomyces cerevisiae including the nucleotide sequence shown in SEQ ID NO: 1, where the sequence shown in SEQ ID NO: 1, from left to right, consists of a ?18˜+203 bp fragment of SNG1 gene of Saccharomyces cerevisiae, a nucleotide fragment of loxp-KanMX4-loxp and a +1446˜+1644 bp fragment of the SNG1 gene of Saccharomyces cerevisiae.
    Type: Application
    Filed: December 10, 2020
    Publication date: December 16, 2021
    Inventors: Xiaoming BAO, Xinning WANG, Wenyan CAO, Weiquan ZHAO, Zailu LI