Abstract: Optical coherence tomography (OCT) angiography (OCTA) data is generated by one or more machine learning systems to which OCT data is input. The OCTA data is capable of visualization in three dimensions (3D) and can be generated from a single OCT scan. Further, motion artifact can be removed or attenuated in the OCTA data by performing the OCT scans according to special scan patterns and/or capturing redundant data, and by the one or more machine learning systems.

Abstract: This application discloses a map generation method performed by an electronic device. The method includes: randomly placing first M sub-level maps of N sub-level maps in a predetermined map region, N>M, and the first M sub-level maps not overlapping with each other and at least one of the first M sub-level maps is not connected to the others of the first M sub-level maps; selecting, among the remaining N?M sub-level maps, one or more to-be-placed sub-level maps; and iteratively placing the to-be-placed sub-level maps at target candidate regions adjacent the at least one of the first M sub-level maps in accordance with a predetermined condition to obtain a target map, wherein the predetermined condition comprises: after a to-be-placed sub-level map is placed at one of the target candidate regions, the sub-level map is connected to the at least one of the first M sub-level maps.

Abstract: The present disclosure provides for a compound according to formula (I) or a pharmaceutically acceptable salt thereof as CaV1.22 activators for the treatment of schizophrenia, bipolar disorder, major depressive disorder, substance use disorder, ADHD, Phelan-McDermid Syndrome, autism spectrum disorder, multiple sclerosis, frontotemporal dementia, Alzheimer's disease, Brugada Syndrome, Short QT syndrome, or early repolarization syndrome.

Abstract: The present disclosure relates to a shared bicycle that can be charged conveniently. The bicycle includes a front fork, a rear fork, a handle mounted on the front fork, a shopping basket mounted on the handle, a solar panel mounted on the shopping basket, and a smart lock mounted on the rear fork. The bicycle further includes a bus for data transmission and charging. One end of the bus is electrically connected to the smart lock, and the other end of the bus is configured with an interface that can be connected to an external circuit. The interface is mounted on the shopping basket. The solar panel is connected to the bus via a wire. The interface of the bus is mounted on the shopping basket without disassembling the cover plate, which provides a large operable space and makes it convenient for charging and data transmission, thereby improving the rescue efficiency.

Abstract: The present disclosure provides salts of lipoic acid choline ester (LACE), crystalline forms thereof, and methods of use thereof. The present disclosure further provides pharmaceutical compositions of LACE salts and methods of use thereof.

Abstract: Provided are a fitness control system and a spinning bicycle. The system includes: a central controlling unit for detecting change information of each parameter of the fitness equipment; and a terminal device for controlling, according to the change information of each parameter of the fitness equipment, a virtual character to simulate movement of a user who uses the fitness equipment in the target fitness scene, and for real-time detecting during a virtual character simulates movement of the user, the road condition information in the target fitness scene, and feeding back to the central controlling unit a control signal matching a set condition. The central controlling unit is also configured to control, according to the control signal, the fitness equipment to generate feedback matching the influence.

Abstract: A device for treatment of organic waste includes a heating unit, a hydrolysis tank, a regulating tank, an aerobic fermentation reactor, an organic waste feeder, an aerobe feeder, a delivery mechanism, a deodorization unit, and an air distributor. The hydrolysis tank is connected to the regulating tank, and the regulating tank is connected to the aerobic fermentation reactor. The delivery mechanism is disposed between the regulating tank and the aerobic fermentation reactor. The heating unit is connected to the hydrolysis tank and is configured to heat an organic material in the hydrolysis tank. The organic waste feeder and the aerobe feeder are connected to the regulating tank. The deodorization unit is disposed on and connected to the aerobic fermentation reactor. The air distributor is disposed in the aerobic fermentation reactor and is configured to provide oxygen to the aerobic fermentation reactor.

Abstract: The present invention relates to crystalline forms of N-(3-(2-(2-hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinanmide and to processes for their preparation. Furthermore, the invention relates to a N pharmaceutical composition comprising said crystalline forms of N-(3-(2-(2-hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-trifluoromethyl)isonicotinamide, and at least one pharmaceutically acceptable excipient. The pharmaceutical composition CA of the present invention can be used as a medicament, in particular for the treatment of cancers.

Abstract: A biological filler includes an embedding agent and an embedded complex. The embedded complex includes a scallop shell powder, 1,5-dihydroxyanthraquinone, and Thiobacillus denitrificans. The embedding agent includes a poly(vinyl alcohol)-sodium alginate blend membrane and a crosslinked composite membrane. The embedded complex is embedded by the embedded agent.

Abstract: A multimedia system may include a main control unit of a bicycle lock, a display unit, and a cloud server. The display unit may include a plurality of display screens. The main control unit may report an electric quantity of the shared bicycle to the cloud server when the bicycle lock is unlocked. The cloud server may send multimedia information to the main control unit when the shared bicycle is at a high level of electric quantity. The main control unit may refrain from turning on the display unit when the shared bicycle is at a low level of electric quantity. The multimedia system may turn on or off a display screen according to the electric quantity of the shared bicycle, and the display screen may display the multimedia information for advertising. The multimedia system may further include a navigation module to provide navigation for users and facilitate user travel.

Abstract: A biological filler includes an embedding agent and an embedded complex. The embedded complex includes a scallop shell powder, 1,5-dihydroxyanthraquinone, and Thiobacillus denitrificans. The embedding agent includes a poly(vinyl alcohol)-sodium alginate blend membrane and a crosslinked composite membrane. The embedded complex is embedded by the embedded agent.

Abstract: Disclosed are a Penicillium oxalicum SDF-25 strain and applications thereof, which relate to the technical field of environmental microorganisms. The Penicillium oxalicum SDF-25 strain has a strain preservation number of CGMCC No. 19272. The Penicillium oxalicum SDF-25 strain can be applied to straw degradation. The Penicillium oxalicum SDF-25 strain provided in the present solution can grow normally at 6 to 37° C. The Penicillium oxalicum SDF-25 strain can secrete a large amount of carboxymethyl cellulase at 10 to 16° C., and still produce enzyme at 6° C. The highest enzymatic activity can reach 993.3 U/mL.

Abstract: A Bacillus subtilis BS40-4 strain is deposited in China General Microbiological Culture Collection Center (CGMCC) with an accession number CGMCC No. 19757.

Abstract: A device for treatment of organic waste includes a heating unit, a hydrolysis tank, a regulating tank, an aerobic fermentation reactor, an organic waste feeder, an aerobe feeder, a delivery mechanism, a deodorization unit, and an air distributor. The hydrolysis tank is connected to the regulating tank, and the regulating tank is connected to the aerobic fermentation reactor. The delivery mechanism is disposed between the regulating tank and the aerobic fermentation reactor. The heating unit is connected to the hydrolysis tank and is configured to heat an organic material in the hydrolysis tank. The organic waste feeder and the aerobe feeder are connected to the regulating tank. The deodorization unit is disposed on and connected to the aerobic fermentation reactor. The air distributor is disposed in the aerobic fermentation reactor and is configured to provide oxygen to the aerobic fermentation reactor.

Abstract: The present disclosure provides salts of lipoic acid choline ester (LACE), crystalline forms thereof, and methods of use thereof. The present disclosure further provides pharmaceutical compositions of LACE salts and methods of use thereof.

Abstract: The present disclosure provides for a compound according to formula (I) or a pharmaceutically acceptable salt thereof as CaV1.22 activators for the treatment of schizophrenia, bipolar disorder, major depressive disorder, substance use disorder, ADHD, Phelan-McDermid Syndrome, autism spectrum disorder, multiple sclerosis, frontotemporal dementia, Alzheimer's disease, Brugada Syndrome, Short QT syndrome, or early repolarization syndrome.

Abstract: The present disclosure provides salts of lipoic acid choline ester (LACE), crystalline forms thereof, and methods of use thereof. The present disclosure further provides pharmaceutical compositions of LACE salts and methods of use thereof.

Abstract: The present disclosure provides salts of lipoic acid choline ester (LACE), crystalline forms thereof, and methods of use thereof. The present disclosure further provides pharmaceutical compositions of LACE salts and methods of use thereof.

Abstract: The present disclosure relates to a multimedia system of a shared bicycle. The multimedia system includes a lock main control unit, a cloud server, and a display unit. The display unit includes a navigation module, a multimedia module, and a mode switching module. The multimedia module includes a data switching sub-module. The mode switching module is configured to switch to a navigation mode or a multimedia mode. The data switching sub-module is configured to switch multimedia information. The display unit broadcasts the multimedia information to achieve advertising purposes. The navigation module provides navigation for a user, which is convenient for the user to travel and can avoid a dangerous behavior of the user. In addition, the data switching sub-module controls the multimedia system to broadcast different multimedia information in different time periods, different environments and different regions, thereby further improving the user experience.

Abstract: The invention provides new solid forms, salts and polymorphs of 1-(((Z)-(1-(2-aminothiazol-4-yl)-2-oxo-2-(((3S,4R)-2-oxo-4-((2-oxooxazolidin-3-yl)methyl)-1-sulfoazetidin-3-yl)amino)ethylidene)amino)oxy)cyclopropanecarboxylic acid (referred to herein as Compound X), pharmaceutical compositions containing them, and processes for their manufacture and use in therapy.