Patents by Inventor Zakauddin T. Chowhan

Zakauddin T. Chowhan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7030162
    Abstract: The invention is directed to pharmaceutical compositions useful in the treatment of migraine. The compositions contain metoclopramide and one or more NSAIDs in unit dosage form. By selecting NSAIDs that are non-acidic or segregating the metoclopramide and NSAID, the storage life of the compositions has been increased. Also disclosed are coordinated dosage forms for the sequential release of drugs. The invention encompasses methods of treating migraine using any of these dosage forms.
    Type: Grant
    Filed: September 26, 2002
    Date of Patent: April 18, 2006
    Assignee: POZEN Inc.
    Inventors: John R. Plachetka, Zakauddin T. Chowhan
  • Publication number: 20030040537
    Abstract: The invention is directed to pharmaceutical compositions useful in the treatment of migraine. The compositions contain metoclopramide and one or more NSAIDs in unit dosage form. By selecting NSAIDs that are non-acidic or segregating the metoclopramide and NSAID, the storage life of the compositions has been increased. Also disclosed are coordinated dosage forms for the sequential release of drugs. The invention encompasses methods of treating migraine using any of these dosage forms.
    Type: Application
    Filed: September 26, 2002
    Publication date: February 27, 2003
    Applicant: POZEN Inc.
    Inventors: John R. Plachetka, Zakauddin T. Chowhan
  • Patent number: 6479551
    Abstract: The invention is directed to pharmaceutical compositions useful in the treatment of migraine. The compositions contain metoclopramide and one or more NSAIDs in unit dosage form. By selecting NSAIDs that are non-acidic or segregating the metoclopramide and NSAID, the storage life of the compositions has been increased. Also disclosed are coordinated dosage forms for the sequential release of drugs. The invention encompasses methods of treating migraine using any of these dosage forms.
    Type: Grant
    Filed: March 3, 2000
    Date of Patent: November 12, 2002
    Assignee: Pozen Inc.
    Inventors: John R. Plachetka, Zakauddin T. Chowhan
  • Patent number: 6224911
    Abstract: This invention is directed to a process for the preparation of enteric coated pharmaceutical dosage forms. This invention is further directed to the aqueous enteric coating dispersions suitable for use in the process and the enteric coated pharmaceutical dosage forms prepared by the process.
    Type: Grant
    Filed: January 18, 1995
    Date of Patent: May 1, 2001
    Assignee: Syntex (U.S.A.) LLC
    Inventors: Zakauddin T. Chowhan, Patrick H. Vo
  • Patent number: 6077539
    Abstract: This invention comprises a non-vasoactive, supra-vasoactive syndrome ("SVS") minimized dosage form for treatment of migraine in a human comprising (i) rapid availability metoclopramide in at least about an effective local gastrointestinal amount; (ii) at least one long acting NSAID such as naproxen sodium in a therapeutically effective amount; (iii) wherein said dosage form is a coordinated dosage form; and, (iv) wherein the dosage form is absent 5HT agonist vasoactive agents, and preparation thereof. Acid-base stable dosage forms are noted. This invention further comprises methods of migraine treatment, and methods for rapid introduction of oral NSAID into the small bowel.
    Type: Grant
    Filed: November 10, 1997
    Date of Patent: June 20, 2000
    Assignee: Pozen, Inc.
    Inventors: John R. Plachetka, Zakauddin T. Chowhan
  • Patent number: 5470580
    Abstract: The present invention relates to directly-compressible naproxen or naproxen sodium compositions comprising spray-dried naproxen or naproxen sodium. The present invention further relates the processes for preparing the directly-compressible naproxen or naproxen sodium compositions, to aqueous mixtures containing naproxen or sodium naproxen suitable for spray-drying and useful in the processes for preparing the directly-compressible compositions, to naproxen or naproxen sodium tablets prepared from the directly-compressible compositions, and to the processes for preparing the naproxen or naproxen sodium tablets.
    Type: Grant
    Filed: July 6, 1994
    Date of Patent: November 28, 1995
    Assignee: Syntex Pharmaceuticals International Limited
    Inventors: Roy Kuramoto, Zakauddin T. Chowhan, Ranal O. Pendleton, Hafez Hafezzadeh
  • Patent number: 5358717
    Abstract: The present invention relates to directly-compressible naproxen or naproxen sodium compositions comprising spray-dried naproxen or naproxen sodium. The present invention further relates the processes for preparing the directly-compressible naproxen or naproxen sodium compositions, to aqueous mixtures containing naproxen or sodium naproxen suitable for spray-drying and useful in the processes for preparing the directly-compressible compositions, to naproxen or naproxen sodium tablets prepared from the directly-compressible compositions, and to the processes for preparing the naproxen or naproxen sodium tablets.
    Type: Grant
    Filed: May 4, 1992
    Date of Patent: October 25, 1994
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Roy Kuramoto, Zakauddin T. Chowhan, Randal O. Pendleton, Hafez Hafezzadeh