Patents by Inventor Zami Aberman

Zami Aberman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR ENRICHMENT OF TARGET CELLS
    Publication number: 20230190822
    Abstract: Disclosed herein are compositions comprising subcellular fractions from expanded placental adherent stromal cells, and methods utilizing same.
    Type: Application
    Filed: May 5, 2021
    Publication date: June 22, 2023
    Inventors: Rachel Ofir, Zami Aberman, Niva Shraga Heled
  • ADHERENT CELLS FROM ADIPOSE OR PLACENTA TISSUES AND USE THEREOF IN THERAPY
    Publication number: 20220378847
    Abstract: A method of treating ischemia in a subject in need thereof is disclosed. The method comprising administering to the subject a therapeutically effective amount of adherent cells of a tissue selected from the group consisting of a placenta and an adipose tissue, thereby treating the ischemia in the subject. A method of treating a medical condition requiring connective tissue regeneration and/or repair is also disclosed.
    Type: Application
    Filed: August 4, 2022
    Publication date: December 1, 2022
    Inventors: Moran Meiron, Amir Toren, Rachel Ofir, Zami Aberman, Nirit Drori-Carmi
  • USE OF ADHERENT STROMAL CELLS FOR ENHANCING HEMATOPOIESIS IN A SUBJECT IN NEED THEREOF
    Publication number: 20220184140
    Abstract: Disclosed herein are methods and compositions comprising adherent stromal cells.
    Type: Application
    Filed: March 7, 2022
    Publication date: June 16, 2022
    Applicant: PLURISTEM LTD.
    Inventor: Zami ABERMAN
  • THERAPEUTIC METHODS AND COMPOSITIONS
    Publication number: 20210338740
    Abstract: Disclosed herein are pharmaceutical compositions and methods comprising or utilizing placental adherent stromal cells. The pharmaceutical compositions may be indicated for ameliorating or treating various disorders, e.g., impaired glucose tolerance. Alternatively, the pharmaceutical composition may be indicated for ameliorating or treating systemic inflammation, e.g., in a subject with impaired glucose tolerance. The pharmaceutical compositions may further include pharmacologically acceptable excipients.
    Type: Application
    Filed: November 6, 2019
    Publication date: November 4, 2021
    Applicant: PLURISTEM LTD.
    Inventors: Zami ABERMAN, Yaacob YANAY, Rachel OFIR, Marc TRITEL, Hoshea Yissachar ALLEN, Niva SHRAGA HELED
  • THERAPEUTIC DOSAGE REGIMENS COMPRISING ADHERENT STROMAL CELLS
    Publication number: 20210228635
    Abstract: Disclosed herein are pharmaceutical compositions and therapeutic dosage regimens comprising or utilizing adherent stromal cells. The adherent stromal cells may be derived e.g. from placental tissue, from adipose tissue, or from bone marrow. The pharmaceutical compositions may be indicated for treating various disorders, e.g. ischemic disorders, hematopoietic disorders, and neurodegenerative disorders, inflammatory disorders, and neoplasms. The pharmaceutical compositions may further include pharmacologically acceptable excipients.
    Type: Application
    Filed: June 10, 2019
    Publication date: July 29, 2021
    Applicant: PLURISTEM LTD.
    Inventors: Zami ABERMAN, Yaacob YANAY, Rachel OFIR, Marc TRITEL
  • METHODS AND COMPOSITIONS FOR TREATING CANCERS AND NEOPLASMS
    Publication number: 20210205370
    Abstract: Described herein are methods of anti-tumor therapy using adherent stromal cells and conditioned medium produced thereby.
    Type: Application
    Filed: February 16, 2017
    Publication date: July 8, 2021
    Inventors: Zami Aberman, Rachel Ofir, Hoshea Yissachar Allen, Ariel Gilert, Niva Shraga Heled
  • ADHERENT STROMAL CELLS DERIVED FROM PLACENTAS OF MULTIPLE DONORS AND USES THEREOF
    Publication number: 20210113627
    Abstract: Pharmaceutical compositions comprising adherent stromal cells (ASCs) are provided. The ASCs are obtained from at least two donors. Articles of manufacture comprising the pharmaceutical compositions together with a delivery device for administering the ASCs to a subject are also provided. Also provided are methods of treating various diseases and conditions that are treatable by administering ASCs to a subject in need of treatment.
    Type: Application
    Filed: December 11, 2020
    Publication date: April 22, 2021
    Inventors: Zami Aberman, Ora Burger, Shai Meretzki
  • METHODS FOR TREATING RADIATION OR CHEMICAL INJURY
    Publication number: 20200306319
    Abstract: Methods for treating radiation or chemical injury are described that comprise administering to a subject a therapeutically effective amount of adherent stromal cells. Methods of preparing adherent stromal cells and pharmaceutical compositions comprising the cells are also described.
    Type: Application
    Filed: June 9, 2020
    Publication date: October 1, 2020
    Applicant: PLURISTEM LTD.
    Inventors: Raphael GORODETSKY, Zami ABERMAN
  • Methods for treating radiation or chemical injury
    Patent number: 10722541
    Abstract: Methods for treating radiation or chemical injury are described that comprise administering to a subject a therapeutically effective amount of adherent stromal cells. Methods of preparing adherent stromal cells and pharmaceutical compositions comprising the cells are also described.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: July 28, 2020
    Assignee: PLURISTEM LTD.
    Inventors: Zami Aberman, Raphael Gorodetsky
  • Adherent cells from placenta and use of same in disease treatment
    Patent number: 10610545
    Abstract: Methods for treating conditions by administration of placenta derived adherent stromal cells to a subject in thereof are provided. Such conditions include skeletal muscle defects, neuropathic pain, and myocardial infarction. Also provided are methods wherein the adherent stromal cells administered are cultured under 2 dimensional or 3 dimensional growth conditions. Also provided are methods in which the cells administered are at least 70% adherent cells from a maternal or fetal portion of the placenta.
    Type: Grant
    Filed: August 25, 2015
    Date of Patent: April 7, 2020
    Assignee: PLURISTEM LTD.
    Inventor: Zami Aberman
  • METHODS AND COMPOSITIONS FOR TUMOR ASSESSMENT
    Publication number: 20200080147
    Abstract: Described herein are methods and articles of manufacture for determining the suitability of a tumor or neoplastic cell to treatment with adherent stromal cells or with conditioned medium derived therefrom.
    Type: Application
    Filed: February 18, 2018
    Publication date: March 12, 2020
    Applicant: PLURISTEM LTD.
    Inventors: Zami ABERMAN, Rachel OFIR, Hoshea Yissachar ALLEN
  • ADHERENT CELLS FROM ADIPOSE OR PLACENTA TISSUES AND USE THEREOF IN THERAPY
    Publication number: 20180256648
    Abstract: A method of treating ischemia in a subject in need thereof is disclosed. The method comprising administering to the subject a therapeutically effective amount of adherent cells of a tissue selected from the group consisting of a placenta and an adipose tissue, thereby treating the ischemia in the subject. A method of treating a medical condition requiring connective tissue regeneration and/or repair is also disclosed.
    Type: Application
    Filed: August 5, 2013
    Publication date: September 13, 2018
    Applicant: Pluristem Ltd.
    Inventors: Moran Meiron, Amir Toren, Rachel Ofir, Zami Aberman, Nirit Drori-Carmi
  • USE OF ADHERENT STROMAL CELLS FOR ENHANCING HEMATOPOIESIS IN A SUBJECT IN NEED THEREOF
    Publication number: 20180015125
    Abstract: Disclosed herein are methods and compositions comprising adherent stromal cells.
    Type: Application
    Filed: March 21, 2016
    Publication date: January 18, 2018
    Inventor: Zami Aberman
  • ADHERENT STROMAL CELLS DERIVED FROM PLACENTAS OF MULTIPLE DONORS AND USES THEREOF
    Publication number: 20180008649
    Abstract: Pharmaceutical compositions comprising adherent stromal cells (ASCs) are provided. The ASCs are obtained from at least two donors. Articles of manufacture comprising the pharmaceutical compositions together with a delivery device for administering the ASCs to a subject are also provided. Also provided are methods of treating various diseases and conditions that are treatable by administering ASCs to a subject in need of treatment.
    Type: Application
    Filed: July 20, 2017
    Publication date: January 11, 2018
    Inventors: Zami Aberman, Ora Burger, Shai Meretzki
  • METHODS FOR TREATING RADIATION OR CHEMICAL INJURY
    Publication number: 20170368106
    Abstract: Methods for treating radiation or chemical injury are described that comprise administering to a subject a therapeutically effective amount of adherent stromal cells. Methods of preparing adherent stromal cells and pharmaceutical compositions comprising the cells are also described.
    Type: Application
    Filed: July 6, 2017
    Publication date: December 28, 2017
    Inventors: Zami Aberman, Raphael Gorodetsky
  • Adherent cells from adipose or placenta tissues and use thereof in therapy
    Patent number: 9517248
    Abstract: A method of treating ischemia in a subject in need thereof is disclosed. The method comprising administering to the subject a therapeutically effective amount of adherent cells of a tissue selected from the group consisting of a placenta and an adipose tissue, thereby treating the ischemia in the subject. A method of treating a medical condition requiring connective tissue regeneration and/or repair is also disclosed.
    Type: Grant
    Filed: February 13, 2014
    Date of Patent: December 13, 2016
    Assignee: Pluristem Ltd.
    Inventors: Moran Meiron, Amir Toren, Rachel Ofir, Zami Aberman, Nirit Drori-Carmi
  • Devices and methods for culture of cells
    Patent number: 9512393
    Abstract: Devices and methods for culture of cells are provided. The devices can comprise a three-dimensional body having multiple two-dimensional surfaces extending inwardly from a periphery of the three-dimensional body towards an interior of the three-dimensional body, wherein the multiple two-dimensional surfaces are configured to support monolayer growth of eukaryotic cells over at least a majority of or all of the surface area of the multiple two-dimensional surfaces.
    Type: Grant
    Filed: August 31, 2013
    Date of Patent: December 6, 2016
    Assignee: Pluristem Ltd.
    Inventors: Harel Kasuto, Eytan Abraham, Zami Aberman
  • ADHERENT CELLS FROM PLACENTA AND USE OF SAME IN DISEASE TREATMENT
    Publication number: 20160058799
    Abstract: Methods for treating conditions by administration of placenta derived adherent stromal cells to a subject in thereof are provided. Such conditions include skeletal muscle defects, neuropathic pain, and myocardial infarction. Also provided are methods wherein the adherent stromal cells administered are cultured under 2 dimensional or 3 dimensional growth conditions. Also provided are methods in which the cells administered are at least 70% adherent cells from a maternal or fetal portion of the placenta.
    Type: Application
    Filed: August 25, 2015
    Publication date: March 3, 2016
    Applicant: Pluristem Ltd.
    Inventor: Zami Aberman
  • METHODS FOR CELL EXPANSION AND USES OF CELLS AND CONDITIONED MEDIA PRODUCED THEREBY FOR THERAPY
    Publication number: 20160022738
    Abstract: A method of cell expansion is provided. The method comprising culturing adherent cells from placenta or adipose tissue under three-dimensional culturing conditions, which support cell expansion.
    Type: Application
    Filed: October 1, 2015
    Publication date: January 28, 2016
    Applicant: Pluristem Ltd.
    Inventors: Shai Meretski, Zami Aberman, Ora Burger
  • Adherent cells from placenta and use of same in disease treatment
    Patent number: 9175262
    Abstract: Methods for treating conditions by administration of placenta derived adherent stromal cells to a subject in thereof are provided. Such conditions include skeletal muscle defects, neuropathic pain, and myocardial infarction. Also provided are methods wherein the adherent stromal cells administered are cultured under 2 dimensional or 3 dimensional growth conditions. Also provided are methods in which the cells administered are at least 70% adherent cells from a maternal or fetal portion of the placenta.
    Type: Grant
    Filed: November 29, 2010
    Date of Patent: November 3, 2015
    Assignee: Pluristerm Ltd.
    Inventor: Zami Aberman