Abstract: Proper timing and combinatorial administration of immunocytokines and Flt3-L combined with vaccination with tumor associated antigens provides an anticancer therapeutic benefit. Sequential administration of GM-CSF after Flt3-L provides improved expansion of mature dendritic cell populations. The expansion of mature dendritic cells can be used to enhance an immune response in the subject.

Abstract: A method is provided for expanding the population of mature dendritic cells in an individual subject. Proper timing of sequential delivery of Flt3-L and GM-CSF provides improved expansion of mature dendritic cell populations over methods currently employed in the art. The expansion of mature dendritic cells can be used to enhance an immune response in the subject. The mature dendritic cells can also be isolated from the subject for use in biological research.

Abstract: Chimeric antitumor compounds for the treatment of cancer are disclosed. The chimeric compounds may be encoded by a nucleic acid. Delivery of the nucleic acid to cells in vivo provides for in vivo production of the antitumor compounds.

Abstract: Described are drug formulations that increase regional delivery of the drugs to cells. Methods for reversibly increasing the hydrophobicity of a drug through hydrolytic ally labile attachment of a hydrophobic moiety and methods for delivering the modified drug to cells is described. Hydrophobic modification increases drug delivery, while lability minimizes entry of the drug into non-target cells.

Abstract: A device for and method of ergonomically removing parts from a parts bin, so that an operator does not have to unnecessarily bend to remove parts, using an open-ended bin, a platform removably contained within the bin, and a mechanism for lifting the platform which is, also, removably contained within the bin. The mechanism for lifting the platform may be a manually operated or automatically operated scissor-type jack, hydraulic cylinder, or pneumatic cylinder. Also, the platform may be vertically adjusted by a spring whose spring constant is chosen to correspond to the weight of the parts within the bin.

Abstract: A device for and method of ergonomically removing parts from a parts bin, so that an operator does not have to unnecessarily bend to remove parts, using an open-ended bin, a platform removably contained within the bin, and a mechanism for lifting the platform which is, also, removably contained within the bin. The mechanism for lifting the platform may be a manually operated or automatically operated scissor-type jack, hydraulic cylinder, or pneumatic cylinder. Also, the platform may be vertically adjusted by a spring whose spring constant is chosen to correspond to the weight of the parts within the bin.