Patents by Inventor Zaver M Bhujwalla

Zaver M Bhujwalla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method to synthesize a biodegradable dextran for agent delivery
    Patent number: 12161727
    Abstract: Disclosed are delivery compositions and methods of making and using these compositions. The delivery compositions comprise a collection of polysaccharide degradable dextran nanopolymers comprising one or more amines having 25% or less cross linking. The polysaccharide degradable dextran nanopolymers may be sphere shaped with a radius in the range of 5 nm to 100 nm.
    Type: Grant
    Filed: May 23, 2019
    Date of Patent: December 10, 2024
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Zaver M. Bhujwalla, Zhihang Chen
  • A METHOD TO SYNTHESIZE A BIODEGRADABLE DEXTRAN FOR AGENT DELIVERY
    Publication number: 20210138085
    Abstract: Disclosed are delivery compositions and methods of making and using these compositions. The delivery compositions comprise a collection of polysaccharide degradable dextran nanopolymers comprising one or more amines having 25% or less cross linking. The polysaccharide degradable dextran nanopolymers may be sphere shaped with a radius in the range of 5 nm to 100 nm.
    Type: Application
    Filed: May 23, 2019
    Publication date: May 13, 2021
    Inventors: Zaver M. BHUJWALLA, Zhihang CHEN
  • DECOY NANOPARTICLES TO DISRUPT CANCER CELL-STROMAL CELL NETWORKS
    Publication number: 20180200194
    Abstract: The present invention relates to compositions and methods for disrupting cancer stromal cell networks using synthetic nanoparticles coated with plasma membranes.
    Type: Application
    Filed: August 12, 2016
    Publication date: July 19, 2018
    Inventors: Zaver M. Bhujwalla, Jiefu Jin, Sridhar Nimmagadda, Balaji Krishnamachary
  • Self-assembled, micropatterned, and radio frequency (RF) shielded biocontainers
    Patent number: 8236259
    Abstract: The present invention relates to a nanoscale or microscale container for encapsulation and delivery of materials or substances, including, but not limited to, cells, drugs, tissue, gels and polymers contained within the container, with subsequent release of the therapeutic materials in situ, methods of fabricating the container by folding a 2D precursor into the 3D container, and the use of the container in in-vivo or in-vitro applications. The container can be in any polyhedral shape and its surfaces can have either no perforations or nano/microscale perforations. The container is coated with a biocompatible metal, e.g. gold, or polymer, e.g. parylene, layer and the surfaces and hinges of the container are made of any metal or polymer combinations.
    Type: Grant
    Filed: July 24, 2006
    Date of Patent: August 7, 2012
    Assignee: Johns Hopkins University
    Inventors: David H. Gracias, Barjor Gimi, Zaver M Bhujwalla