Publication number: 20230295149
Abstract: A monobactam compound of formula (I), a preparation thereof, and a use thereof as antibiotic agents for the treatment of bacterial infections are provided. In the formula (I), M is hydrogen or a pharmaceutically acceptable salt forming cation, R1 and R2 represent independently of one another hydrogen or methyl, W represents a bond or O, X represents CR4 or N, R4 represents halogen, R3 represents hydrogen, amino, hydroxy, (C1-C6)-alkyl, or a 4-, 5- or 6-membered nitrogen-containing heterocycle.
Type:
Application
Filed:
July 16, 2020
Publication date:
September 21, 2023
Applicant:
NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES
Inventors:
Zhixiang YANG, Haikang YANG, Jinbo JI, Lijuan ZHAI, Lili HE, Jian SUN, Koko MYO, Dong TANG, Yuanyu GAO, Yuanbai LIU, Yangxiu MU, Jingwen JI, Zafar IQBAL, Zawmin THU, Rui JIANG, Xueqin MA, Jianqiang YU
