Patents by Inventor Zbigniew P. Kortylewicz

Zbigniew P. Kortylewicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MIBG analogs and uses thereof
    Patent number: 10874752
    Abstract: Compounds and compositions for targeting cells expressing norepinephrine transporter, and methods of making and using the same. The compounds comprise MIBG analogs conjugated to active agents for treatment and/or diagnosis of various conditions, including neuroblastoma.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: December 29, 2020
    Assignee: Board of Regents of The University of Nebraska
    Inventors: Janina Baranowska-Kortylewicz, Zbigniew P. Kortylewicz
  • TARGETED RADIOLABELED COMPOUNDS AND THEIR USE FOR THE TREATMENT AND DIAGNOSIS OF CANCER
    Publication number: 20200046861
    Abstract: Methods of using butyrylcholinesterase targeted, and optionally androgen receptor targeted radiolabeled compounds, e.g., cycloSalingenyl pyrimidine nucleoside monophosphates, for targeted delivery of cytotoxic and/or imaging compounds to cancer cells.
    Type: Application
    Filed: August 19, 2019
    Publication date: February 13, 2020
    Inventors: Janina Baranowska-Kortylewicz, Zbigniew P. Kortylewicz
  • MIBG ANALOGS AND USES THEREOF
    Publication number: 20180256761
    Abstract: Compounds and compositions for targeting cells expressing norepinephrine transporter, and methods of making and using the same. The compounds comprise MIBG analogs conjugated to active agents for treatment and/or diagnosis of various conditions, including neuroblastoma.
    Type: Application
    Filed: September 23, 2016
    Publication date: September 13, 2018
    Inventors: Janina Baranowska-Kortylewicz, Zbigniew P. Kortylewicz
  • TARGETED RADIOLABELED COMPOUNDS AND THEIR USE FOR THE TREATMENT AND DIAGNOSIS OF CANCER
    Publication number: 20170151355
    Abstract: Method of using androgen receptor and/or butyrylcholinesterase targeted radiolabeled compounds, e.g., cycloSalingenyl pyrimidine nucleoside monophosphates, for the treatment and diagnosis of cancer.
    Type: Application
    Filed: February 13, 2017
    Publication date: June 1, 2017
    Inventors: Janina Baranowska-Kortylewicz, Zbigniew P. Kortylewicz
  • Radiologic agents for monitoring alzheimer's disease progression and Evaluating a Response to Therapy and processes for the preparation of such agents
    Patent number: 9315534
    Abstract: Disclosed are certain cycloSalingenyl pyrimidine nucleoside monophosphates comprising positron emitters or gamma-emitting radiohalides, uses thereof for monitoring Alzheimer's disease progression and evaluating response to therapy and process for their preparation.
    Type: Grant
    Filed: August 8, 2008
    Date of Patent: April 19, 2016
    Assignee: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
    Inventors: Zbigniew P. Kortylewicz, Janina Baranowska-Kortylewicz
  • TARGETED RADIOLABELED COMPOUNDS AND THEIR USE FOR THE TREATMENT AND DIAGNOSIS OF CANCER
    Publication number: 20120269725
    Abstract: Method of using androgen receptor and/or butyrylcholinesterase targeted radiolabeled compounds, e.g., cycloSalingenyl pyrimidine nucleoside monophosphates, for the treatment and diagnosis of cancer.
    Type: Application
    Filed: December 23, 2010
    Publication date: October 25, 2012
    Inventors: Janine Baranowska-Kortylewicz, Zbigniew P. Kortylewicz
  • Radiologic Agents for Monitoring Alzheimer's Disease Progression and Evaluating a Response to Therapy and Processes for the Preparation of Such Agents
    Publication number: 20090117041
    Abstract: Disclosed are certain cycloSalingenyl pyrimidine nucleoside monophosphates comprising positron emitters or gamma-emitting radiohalides, uses thereof for monitoring Alzheimer's disease progression and evaluating response to therapy and process for their preparation.
    Type: Application
    Filed: August 8, 2008
    Publication date: May 7, 2009
    Inventors: Zbigniew P. Kortylewicz, Janina Baranowska-Kortylewicz