Patents by Inventor Zbigniew S. Matusiak

Zbigniew S. Matusiak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5032607
    Abstract: The use of an olefinic compound of the formulaR.sup.1 R.sup.2 R.sup.3 C--CR.sup.4 =CR.sup.5 R.sup.6 (I),wherein R.sup.1 is a heterocyclyl radical selected from 1,2,4 -triazolyl, imidazolyl, 5-(1-6C alkyl)imidazol-1-yl, pyridyl and pyrimidinyl; R.sup.2 and R.sup.3, which may be the same or different, are each a hydrogen atom or a 1-6C alkyl radical; R.sup.4 is a phenyl or pyridyl radical, optionally bearing one or more substitutents selected from halogen atoms, amino, cyano, carbamoyl and nitro radicals, 1-6C alkyl, halogenoalkyl, alkoxy, halogenoalkoxy, alkylamino and alkylcarbamoyl radicals, di(1-6C alkyl)amino, di(1-6C alkyl)carbamoyl and 2-6C alkoxycarbonyl radicals; R.sup.5 is a hydrogen or halogen atom, a 1-6C alkyl radical or a phenyl radical optionally bearing one or more substituents as defined above for R.sup.4 ; and R.sup.6 is a phenyl or pyridyl radical optionally bearing one or more substitutents as defined above for R.sup.
    Type: Grant
    Filed: June 21, 1989
    Date of Patent: July 16, 1991
    Assignee: Imperial Chemical Industries PLC
    Inventors: Francis T. Boyle, Zbigniew S. Matusiak, James M. Wardleworth
  • Patent number: 4999364
    Abstract: Azole derivatives of the formulasR.sup.1 --CR.sup.2 R.sup.3 --CHR.sup.4 --CR.sup.5 R.sup.6 --R.sup.7are described;wherein R.sup.1 is a heterocyclyl radicla selected from 1,2,4-triazolyl, optionally-substituted imidazolyl, pyridyl and pyrimidinyl radicals; R.sup.2 and R.sup.3, which may be the same or different, are each a hydrogen atom or a 1-6C alkyl radical; R.sup.5 and R.sup.6, which may be the same or different, are each a hydrogen or fluorine atom or a 1-6C alkyl radical; one of R.sup.4 and R.sup.7 is a 2-pyridyl or 2-thienyl radical, optionally bearing one or more substituents selected from halogen atoms, cyano radicals and 1-4C halogenoalkyl and halogenoalkoxy radicals, and the other of R.sup.4 and R.sup.7 is a 4-cyanophenyl radical or a 2-pyridyl or 2-thienyl radical optionally substituted as defined above. Processes for their preparation are described, as is their use as aromatase inhibitors, for example in the treatment of cancer, as plant antifungal agents or as plant growth regulatory agents.
    Type: Grant
    Filed: August 7, 1989
    Date of Patent: March 12, 1991
    Assignee: Imperial Chemical Industries PLC
    Inventors: Francis T. Boyle, Zbigniew S. Matusiak
  • Patent number: 4910212
    Abstract: A heterocyclic compound of the formula I, as shown hereafter in these claims in which n is 0 or 1; A is a 1-4C alkylene radical which may optionally bear one or more 1-4C alkyl substituents; R.sup.1 and R.sup.2, which may be the same or different, are each a hydrogen or halogen atom, an amino, carbamoyl, cyano, hydroxy, nitro or sulphamoyl radical, a 1-6C alkyl, halogenoalkyl, alkoxy, halogenoalkoxy, alkylamino, alkylcarbamoyl or alkylsulphamoyl radical, a di(1-6C alkyl)-amino, di(1-6C alkyl)carbamoyl or di(1-6C alkyl)sulphamoyl radical, or a 2-7C alkoxycarbonyl radical; m is an integer of 1 to 5, R.sup.3 is a hydrogen or halogen atom or a 1-6C alkyl or halogenoalkyl radical; and R.sup.
    Type: Grant
    Filed: February 16, 1988
    Date of Patent: March 20, 1990
    Assignee: Imperial Chemical Industries PLC
    Inventors: Francis T. Boyle, Zbigniew S. Matusiak, Brian S. Tait
  • Patent number: 4866086
    Abstract: The use of an olefinic compound of the formulaR.sup.1 R.sup.2 R.sup.3 C-CR.sup.4 =CR.sup.5 R.sup.6 (I)wherein R.sup.1 is a heterocyclyl radical selected from 1,2,4-triazolyl, imidazolyl, 5-(1-6C alkyl)imidazol-1-yl, pyridyl and pyrimidinyl; R.sup.2 and R.sup.3, which may be the same or different, are each a hydrogen atom or a 1-6C alkyl radical; R.sup.4 is a phenyl or pyridyl radical, optionally bearing one or more substitutents selected from halogen atoms, amino, cyano, carbamoyl and nitro radicals, 1-6C alkyl, halogenoalkyl, alkoxy, halogenoalkoxy, alkylamino and alkylcarbamoyl radicals, di(1-6C alkyl)amino, di(1-6C alkyl)carbamoyl and 2-6C alkoxycarbonyl radicals; R.sup.5 is a hydrogen or halogen atom, a 1-6C alkyl radical or a phenyl radical optionally bearing one or more substituents as defined above for R.sup.4 ; and R.sup.6 is a phenyl or pyridyl radical optionally bearing one or more substituents as defined above for R.sup.
    Type: Grant
    Filed: July 13, 1988
    Date of Patent: September 12, 1989
    Assignee: Imperial Chemical Industries PLC
    Inventors: Francis T. Boyle, Zbigniew S. Matusiak, James M. Wardleworth