Patents by Inventor Zdenka Ludmila Jonak

Zdenka Ludmila Jonak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antigen binding proteins
    Patent number: 9085622
    Abstract: The present disclosure relates to antigen binding proteins, such as antibodies, that bind to HER3, polynucleotides encoding such antigen binding proteins, pharmaceutical compositions comprising said antigen binding proteins and methods of manufacture. The present disclosure also concerns the use of such antigen binding proteins in the treatment or prophylaxis of diseases associated with breast cancer, ovarian cancer, prostate cancer, bladder cancer, pancreatic, gastric, melanoma and other cancers that overexpress HER3.
    Type: Grant
    Filed: September 2, 2011
    Date of Patent: July 21, 2015
    Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: Neil James Clarke, Kyung Oh Johanson, Zdenka Ludmila Jonak, Alexander H. Taylor, Christopher B. Hopson, Stephen H. Trulli, Zdenka Haskova, Judithann M. Lee, John R. White, Yu Xue
  • Compounds
    Patent number: 8828384
    Abstract: The present invention relates to an antibody which has multiple specificities. In particular the antibody of the present invention binds to (cross react with) human IL-8, Gro-alpha, Gro-beta, Gro-gamma, and ENA-78.
    Type: Grant
    Filed: June 26, 2013
    Date of Patent: September 9, 2014
    Assignee: GlaxoSmithKline LLC
    Inventors: Stephanie Jane Clegg, Eric Dobrzynski, Jonathan H. Ellis, Volker Germaschewski, Alexis Pual Godillot, Zdenka Ludmila Jonak, Alan P. Lewis, John R. White
  • NOVEL COMPOUNDS
    Publication number: 20140010807
    Abstract: The present invention relates to an antibody which has multiple specificities. In particular the antibody of the present invention binds to (cross react with) human IL-8, Gro-alpha, Gro-beta, Gro-gamma, and ENA-78.
    Type: Application
    Filed: June 26, 2013
    Publication date: January 9, 2014
    Inventors: Stephanie Jane CLEGG, Eric Dobrzynski, Jonathan H. Ellis, Volker Germaschewski, Alexis Paul Godillot, Zdenka Ludmila Jonak, Alan P. Lewis, John R. White
  • Compounds
    Patent number: 8496932
    Abstract: The present invention relates to an antibody which has multiple specificities. In particular the antibody of the present invention binds to (cross react with) human IL-8, Gro-alpha, Gro-beta, Gro-gamma, and ENA-78.
    Type: Grant
    Filed: April 16, 2008
    Date of Patent: July 30, 2013
    Assignee: GlaxoSmithKline
    Inventors: Stephanie Jane Clegg, Eric Dobrzynski, Jonathan H. Ellis, Volker Germaschewski, Alexis Paul Godillot, Zdenka Ludmila Jonak, Alan P. Lewis, John R. White
  • NOVEL ANTIGEN BINDING PROTEINS
    Publication number: 20130156779
    Abstract: The present disclosure relates to antigen binding proteins, such as antibodies, that bind to HER3, polynucleotides encoding such antigen binding proteins, pharmaceutical compositions comprising said antigen binding proteins and methods of manufacture. The present disclosure also concerns the use of such antigen binding proteins in the treatment or prophylaxis of diseases associated with breast cancer, ovarian cancer, prostate cancer, bladder cancer, pancreatic, gastric, melanoma and other cancers that overexpress HER3.
    Type: Application
    Filed: September 2, 2011
    Publication date: June 20, 2013
    Inventors: Neil James Clarke, Kyung Oh Johanson, Zdenka Ludmila Jonak, Alexander H. Taylor, Christopher B. Hopson, Stephen H. Trulli, Zdenka Haskova, Judithann M. Lee, John R. White, Yu Xue
  • NOVEL USES
    Publication number: 20120315267
    Abstract: The present invention relates to antibodies which multiple antigen specificities and their use in treating human diseases
    Type: Application
    Filed: February 9, 2011
    Publication date: December 13, 2012
    Applicant: GLAXOSMITHKLINE LLC
    Inventors: Stephanie Jane Clegg, Eric Dobrzynski, Jonathan Henry Ellis, Volker Germaschewski, Alexis Paul Godillot, Zdenka Ludmila Jonak, Alan Peter Lewis, John Richard White
  • NOVEL COMPOUNDS
    Publication number: 20110229475
    Abstract: The present invention relates to an antibody which has multiple specificities. In particular the antibody of the present invention binds to (cross react with) human IL-8, Gro-alpha, Gro-beta, Gro-gamma, and ENA-78.
    Type: Application
    Filed: April 16, 2008
    Publication date: September 22, 2011
    Inventors: Stephanie Jane Clegg, Eric Dobrzynski, Jonathan H. Ellis, Volker Germaschewski, Alexis Paul Godillot, Zdenka Ludmila Jonak, Alan P. Lewis, John R. White
  • METHODS OF TREATING CANCER BY ADMINISTERING HUMAN IL-18 COMBINATIONS
    Publication number: 20100196310
    Abstract: The present invention relates generally to the use of human IL-18 combinations in the treatment of various forms of solid tumors and lymphomas. In particular, the present invention relates to: (1) combinations of human IL-18 with monoclonal antibodies against antigens that are expressed on the surface of cancer cells; and (2) combinations of human IL-18 with chemotherapeutic agents.
    Type: Application
    Filed: March 20, 2008
    Publication date: August 5, 2010
    Applicant: SMITHKLINE BEECHAM CORPORATION
    Inventors: Zdenka Haskova, Zdenka Ludmila Jonak, Stephen H. Trulli, Margaret N. Whitacre
  • NOVEL USES
    Publication number: 20100111945
    Abstract: The present invention relates generally to the use of human IL-18 combinations in the treatment of cancers. In particular, the present invention relates to combination of human IL-18 and an anti-CD20 antibody.
    Type: Application
    Filed: March 20, 2008
    Publication date: May 6, 2010
    Inventors: Zdenka Haskova, Zdenka Ludmila Jonak, Stephen H. Trulli, John F. Toso, Margaret N. Whitacre
  • METHODS OF TREATING CANCER BY ADMINISTERING HUMAN IL-18 COMBINATIONS
    Publication number: 20090035258
    Abstract: The present invention relates generally to the use of human IL-18 combinations in the treatment of various forms of solid tumors and lymphomas. In particular, the present invention relates to: (1) combinations of human IL-18 with monoclonal antibodies against antigens that are expressed on the surface of cancer cells; and (2) combinations of human IL-18 with chemotherapeutic agents.
    Type: Application
    Filed: March 20, 2008
    Publication date: February 5, 2009
    Inventors: Zdenka Haskova, Zdenka Ludmila Jonak, Stephen H. Trulli, Margaret N. Whitacre
  • NOVEL USES
    Publication number: 20080274078
    Abstract: The present invention relates generally to the use of human IL-18 combinations in the treatment of cancers. In particular, the present invention relates to combination of human IL-18 and an anti-CD20 antibody.
    Type: Application
    Filed: March 20, 2008
    Publication date: November 6, 2008
    Inventors: Zdenka HASKOVA, Zdenka Ludmila JONAK, Stephen H. TRULLI, John F. TOSO, Margaret N. WHITACRE
  • NOVEL COMPOUNDS
    Publication number: 20080262203
    Abstract: The present invention relates to an antibody which has multiple specificities. In particular the antibody of the present invention binds to (cross react with) human IL-8, Gro-alpha, Gro-beta, Gro-gamma, and ENA-78.
    Type: Application
    Filed: April 16, 2008
    Publication date: October 23, 2008
    Inventors: Stephanie Jane Clegg, Eric Dobrzynski, Jonathan H. Ellis, Volker Germaschewski, Alexis Paul Godillot, Zdenka Ludmila Jonak, Alan P. Lewis, John R. White
  • Nucleic acids encoding anti-human ???3 and ???5 antibodies
    Patent number: 7087405
    Abstract: This invention relates to novel humanized and other recombinant or engineered antibodies or monoclonal antibodies to a human ?v subunit-containing heterodimeric integrin receptors and to the genes encoding same. Such antibodies are useful for the therapeutic and/or prophylactic treatment of disorders mediated by such receptors, such as cancer, in human patients.
    Type: Grant
    Filed: May 9, 2002
    Date of Patent: August 8, 2006
    Assignee: SmithKline Beecham Corporation
    Inventors: Kyung O Johanson, Zdenka Ludmila Jonak, Alexander Taylor, Stephen H Trulli
  • Nucleic acids encoding anti-human alphanubeta3 and alphanubeta5 antibodies
    Publication number: 20030004317
    Abstract: This invention relates to novel humanized and other recombinant or engineered antibodies or monoclonal antibodies to a human &agr;v subunit-containing heterodimeric integrin receptors and to the genes encoding same. Such antibodies are useful for the therapeutic and/or prophylactic treatment of disorders mediated by such receptors, such as cancer, in human patients.
    Type: Application
    Filed: May 9, 2002
    Publication date: January 2, 2003
    Applicant: SmithKline Beecham Corporation
    Inventors: Kyung O. Johanson, Zdenka Ludmila Jonak, Alexander Taylor, Stephen H. Trulli
  • Anti-human .alpha..sub.v .beta..sub.3 and .alpha..sub.v .beta..sub.5 antibodies
    Patent number: 6160099
    Abstract: This invention relates to novel humanized and other recombinant or engineered antibodies or monoclonal antibodies to a human .alpha..sub.v subunit-containing heterodimeric integrin receptors and to the genes encoding same. Such antibodies are useful for the therapeutic and/or prophylactic treatment of disorders mediated by such receptors, such as cancer, in human patients.
    Type: Grant
    Filed: November 24, 1998
    Date of Patent: December 12, 2000
    Inventors: Zdenka Ludmila Jonak, Alexander Taylor, Stephen H Trulli, Kyung O Johanson