Abstract: An implantable medical device, e.g., an implantable pulse generator, having a non-metal sealed housing and method of making same. An exemplary embodiment of the device includes a replenishable power source, coupling electronic components configured to generate a pulse signal to the replenishable power source, and an inorganic coating covering the electronic components and the power source to seal, preferably hermetically, the electronic components and the power source from a body environment.

Abstract: Methods of locating an optimal site within a brain of a patient for deep brain stimulation include positioning a guiding cannula in a lumen of a main cannula, passing a microelectrode through a lumen of the guiding cannula into the brain, adjusting an insertion depth and a longitudinal angle of the guiding cannula such that the microelectrode locates the optimal site for the deep brain stimulation, and passing a distal end of a macroelectrode or a deep brain stimulation lead through the lumen of the main cannula and into the brain at the optimal site.

Abstract: Systems for locating an optimal site within a brain of a patient for deep brain stimulation include a main cannula having an internal lumen, a guiding cannula having a bent distal end portion configured to pass through the lumen of the main cannula and guide a microelectrode into the brain, a depth adjustment mechanism configured to adjust an insertion depth of the guiding cannula, and a longitudinal angle adjustment device configured to adjust a longitudinal angle of the guiding cannula. The depth adjustment mechanism and longitudinal angle adjustment device adjust a position of the guiding cannula such that the microelectrode locates the optimal site for the deep brain stimulation.

Abstract: A connector is configured to couple an implantable pulse generator (IPG) to an electrical stimulation lead or electrical leads while allowing the implantable pulse generator to be hermetically sealed within a case assembly. The connector includes a resilient body having a lead insertion lumen defined therein. Connector contacts for connecting to multiple contacts at the proximal end of the stimulation may be disposed along the length of the insertion lumen as an array. The connector contacts are configured to be coupled to lead extensions or leads, which direct electrical stimuli to a desired body location.

Abstract: An implantable medical device, e.g., a stimulator, having a sealed housing and method of making the same. An exemplary embodiment of the device includes a case frame defining a cavity, the cavity extending at least substantially through the case frame, which cavity may contain electronics or a power source, and at least one lid configured to be sealingly coupled to the case frame. A feedthru opening may also be included in the case frame.