Patents by Inventor Zebo JIANG

Zebo JIANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating gefitinib-resistant non-small-cell lung cancer
    Patent number: 9597299
    Abstract: The present invention relates to a method for treating gefitinib-resistant non-small-cell lung cancer (NSCLC) comprising administering an effective amount of a resveratrol analog, (Z)3,4,5,4?-tetramethoxystilbene (TMS), to a subject in need thereof. The present invention also relates to a method for inducing apoptosis in gefitinib-resistant NSCLC cells comprising contacting the resveratrol analog to the cells at an effective amount. The present methods are mediated by different signaling pathways connected to cell proliferation and differentiation such as mTOR, JNK, and certain EGFR phosphorylated tyrosine kinase.
    Type: Grant
    Filed: February 17, 2015
    Date of Patent: March 21, 2017
    Assignee: Macau University of Science and Technology
    Inventors: Lai-Han Leung, Xing-Xing Fan, Liang Liu, Zebo Jiang
  • Method For Treating Gefitinib-Resistant Non-Small-Cell Lung Cancer
    Publication number: 20160158163
    Abstract: The present invention relates to a method for treating gefitinib-resistant non-small-cell lung cancer (NSCLC) comprising administering an effective amount of a resveratrol analogue, (Z)3,4,5,4?-tetramethoxystilbene (TMS), to a subject in need thereof. The present invention also relates to a method for inducing apoptosis in gefitinib-resistant NSCLC cells comprising contacting the resveratrol analogue to the cells at an effective amount. The present methods are mediated by different signaling pathways connected to cell proliferation and differentiation such as mTOR, JNK, and certain EGFR phosphorylated tyrosine kinase.
    Type: Application
    Filed: February 17, 2015
    Publication date: June 9, 2016
    Inventors: Lai-Han LEUNG, Xing-Xing FAN, Liang LIU, Zebo JIANG