Patents by Inventor Zejian Ding

Zejian Ding has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • KAPPA OPIOID RECEPTOR PEPTIDE AMIDE LIGANDS
    Publication number: 20250092091
    Abstract: The present invention provides kappa opioid receptor peptide agonists, methods for preparing these compounds, compositions comprising these kappa opioid receptor peptide agonists, and methods of using the kappa opioid receptor peptide agonists to treat pain or other conditions.
    Type: Application
    Filed: November 27, 2024
    Publication date: March 20, 2025
    Inventors: Subo Liao, Jun Yang, Jinliang Lv, Zongquan Liao, Hao Zhou, Jueyuan Gao, Tianpeng Xie, Quanli Yang, Lei Wang, Zejian Ding
  • Kappa opioid receptor peptide amide ligands
    Patent number: 12215173
    Abstract: The present invention provides kappa opioid receptor peptide agonists, methods for preparing these compounds, compositions comprising these kappa opioid receptor peptide agonists, and methods of using the kappa opioid receptor peptide agonists to treat pain or other conditions.
    Type: Grant
    Filed: August 7, 2020
    Date of Patent: February 4, 2025
    Assignees: Humanwell Pharmaceutical US, Inc., Yichang Humanwell Pharmaceuticals Co. Ltd.
    Inventors: Subo Liao, Jun Yang, Jinliang Lv, Zongquan Liao, Hao Zhou, Jueyuan Gao, Tianpeng Xie, Quanli Yang, Lei Wang, Zejian Ding
  • SIGMA-1 RECEPTOR ANTAGONISTS AND THEIR APPLICATIONS
    Publication number: 20240317745
    Abstract: The present disclosure is directed to a class of Sigma-1 receptor small molecule antagonists, their pharmaceutical compositions, preparation methods, and uses. The Sigma-1 receptor small molecule antagonists are shown in formula (I), with specific substituents and definitions described in the specification. These Sigma-1 receptor small molecule antagonists exhibit good binding and antagonistic activity with the Sigma-1 receptor. The invention includes these compounds or their pharmaceutical compositions and their use in treating and/or preventing pain disorders related to the Sigma-1 receptor.
    Type: Application
    Filed: March 14, 2024
    Publication date: September 26, 2024
    Inventors: Shuo Zhao, Subo Liao, Jun Yang, Hao Zhou, Zejian Ding, Yao He, Xiongjun Mou, Youjian Ning, Xin Zheng
  • SOMATOSTATIN RECEPTOR SUBTYPE 4 (SSTR4) AGONISTS AND THEIR APPLICATIONS
    Publication number: 20240174693
    Abstract: The invention discloses a nitrogen-containing heterocyclic derivative of a somatostatin receptor subtype 4 (SSTR4) small molecule agonist and its pharmaceutical composition, preparation method, and use. The nitrogen-containing heterocyclic derivative of the SSTR4 small molecule agonist is represented by formula (I), and the specific substituents and definitions are as described in the specification. The nitrogen-containing heterocyclic derivatives of SSTR4 small molecule agonists exhibit good binding and agonistic activities with SSTR4. Such compounds or their pharmaceutical compositions have great potential in treating and/or preventing pain disorders related to SSTR4 receptor.
    Type: Application
    Filed: November 7, 2023
    Publication date: May 30, 2024
    Inventors: Shuo Zhao, Subo Liao, Ming Li, Jun Yang, Hao Zhou, Zejian Ding, Xin Zheng, Youjian Ning, Dali Liang, Rong Liu, Zewen Liu
  • KAPPA OPIOID RECEPTOR PEPTIDE AMIDE AGONISTS
    Publication number: 20210040150
    Abstract: The present invention provides kappa opioid receptor peptide agonists, methods for preparing these compounds, compositions comprising these kappa opioid receptor peptide agonists, and methods of using the kappa opioid receptor peptide agonists to treat pain or other conditions.
    Type: Application
    Filed: August 7, 2020
    Publication date: February 11, 2021
    Inventors: Subo Liao, Jun Yang, Jinliang Lv, Zongquan Liao, Hao Zhou, Jueyuan Gao, Tianpeng Xie, Quanli Yang, Lei Wang, Zejian Ding