Patents by Inventor Zejuan LI

Zejuan LI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210338835
    Abstract: A nanoparticle delivery system designed for sustained delivery of microRNA-150 (miR-150) to FLT3-overexpressing acute myeloid leukemia (AML) cells, the delivery system comprising poly(amidoamine) (PAMAM) dendrimers complexed with miR-150, wherein at least one dendrimer is surface-functionalized with a ligand specific for FLT3 receptor, and methods for treating AML characterized by FLT3-overexpression are provided.
    Type: Application
    Filed: July 14, 2021
    Publication date: November 4, 2021
    Inventors: Jianjun Chen, Seungpyo Hong, Xi Jiang, Zejuan Li
  • Patent number: 11097014
    Abstract: A nanoparticle delivery system designed for sustained delivery of microRNA-150 (miR-150) to FLT3-overexpressing acute myeloid leukemia (AML) cells, the delivery system comprising poly(amidoamine) (PAMAM) dendrimers complexed with miR-150, wherein at least one dendrimer is surface-functionalized with a ligand specific for FLT3 receptor, and methods for treating AML characterized by FLT3-overexpression are provided.
    Type: Grant
    Filed: June 14, 2017
    Date of Patent: August 24, 2021
    Assignees: University of Cincinnati, Board of Trustees of the University of Illinois, University of Chicago
    Inventors: Jianjun Chen, Seungpyo Hong, Xi Jiang, Zejuan Li
  • Publication number: 20190175754
    Abstract: A nanoparticle delivery system designed for sustained delivery of microRNA-150 (miR-150) to FLT3-overexpressing acute myeloid leukemia (AML) cells, the delivery system comprising poly(amidoamine) (PAMAM) dendrimers complexed with miR-150, wherein at least one dendrimer is surface-functionalized with a ligand specific for FLT3 receptor, and methods for treating AML characterized by FLT3-overexpression are provided.
    Type: Application
    Filed: June 14, 2017
    Publication date: June 13, 2019
    Inventors: Jianjun CHEN, Seungpyo HONG, Xi JIANG, Zejuan LI