Patents by Inventor Zengfu SHANG

Zengfu SHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for determining the repair activity of non-homologous end joining
    Patent number: 9863933
    Abstract: The invention discloses a method for determining the repair activity of NHEJ. In this method, HPRT gene is mutated by using a site-directed gene mutation technology, and plasmid transfection, and 6-TG treatment are performed. By means of the method of the invention, the NHEJ repair activity level of cells can be observed by measuring the cell viability. The method can be used for screening the effects of different drugs and different genes on the NHEJ repair activity.
    Type: Grant
    Filed: August 18, 2015
    Date of Patent: January 9, 2018
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Fenju Liu, Jie Du, Jiahua Yu, Haowen Zhang, Zengfu Shang, Yushuo Zhang
  • Method for Determining the Repair Activity of Non-Homologous End Joining
    Publication number: 20170254799
    Abstract: The invention discloses a method for determining the repair activity of NHEJ. In this method, HPRT gene is mutated by using a site-directed gene mutation technology, and plasmid transfection, and 6-TG treatment are performed. By means of the method of the invention, the NHEJ repair activity level of cells can be observed by measuring the cell viability. The method can be used for screening the effects of different drugs and different genes on the NHEJ repair activity.
    Type: Application
    Filed: August 18, 2015
    Publication date: September 7, 2017
    Inventors: Fenju LIU, Jie DU, Jiahua YU, Haowen ZHANG, Zengfu SHANG, Yushuo ZHANG