Patents by Inventor Zengliang Zhang
Zengliang Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11642388Abstract: An antidepressant compound preparation and a preparation method for same were disclosed, The antidepressant includes the following raw materials of Hypericum perforatum L., Paeonia lactiflora Pall., Gardenia jasminoides Ellis, Albizia julibrissin Durazz. and Moutan cortex. The raw materials are weighed in proportion to obtain extracts respectively, and the extracts are mixed to prepare a compound preparation. The compound preparation prepared by the present invention has the advantages of simple preparation, safety, low toxic and side effects, no dependence, etc., and can effectively alleviate depression mood.Type: GrantFiled: November 26, 2020Date of Patent: May 9, 2023Assignees: CHENLAND NUTRITION ALS INC., QINGDAO CHENLAND PHARMACEUTICAL TECHNOLOGY DEVELOPMENT CO., LTD.Inventors: Shengcan Zou, Jiancheng Zong, Wenyu Li, Lei Zong, Zengliang Zhang, Shanglong Wang
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Publication number: 20230125425Abstract: The present disclosure relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine extract composition with function of regulating depressive emotion and preparation method and traditional Chinese medicine preparation thereof. The composition consists of the following traditional Chinese medicine extracts in parts by weight: 40-80 parts of Hypericum perforatum extract, 10-40 parts of Acanthopanax senticosus extract, and 2-20 parts of Tree peony root bark extract. Compared with the prior art, the traditional Chinese medicine extract composition of the present disclosure has remarkable effect of alleviating depressive emotion, and is a safe and effective dietary supplement. In addition, it also has the effect of helping sleep. The composition has small side effects and no dependence, has a small dosage, and can be made into various dosage forms suitable for wide application.Type: ApplicationFiled: December 20, 2019Publication date: April 27, 2023Applicant: CHENLAND NUTRITIONALS, INC.Inventors: Shengcan ZOU, Zengliang ZHANG, Wenyu LI, Shanglong WANG, Lei ZONG, Jiancheng ZONG
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Publication number: 20230118351Abstract: This application belongs to the field of biotechnology and discloses a method for producing a clam active peptide. The method for producing a clam active peptide comprises cleaning fresh clam meat with water, adding water and homogenizing with a colloid mill to prepare a clam meat slurry; adding water and complex protease for enzymolysis of the clam meat slurry, and heating to inactivate enzyme after the enzymolysis; centrifuging to collect an enzymatic hydrolyzate, capturing the enzymatic hydrolyzate having a molecular weight of lower than 2 KDa through microfiltration-ultrafiltration-nanofiltration membrane filtration, and drying to obtain the clam active peptide.Type: ApplicationFiled: February 20, 2020Publication date: April 20, 2023Applicants: CHENLAND NUTRITIONALS, INC., QINGDAO CHENLAND PHARMACEUTICAL TECHNOLOGY DEVELOPMENT CO., LTD.Inventors: Tingfeng CAO, Fang FAN, Shengcan ZOU, Guojunnan FENG, Jinli LIU, Xiu LU, Zengliang ZHANG
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Patent number: 11525815Abstract: The present invention discloses a method for product quality control and fingerprint detection of an epimedium brevicornu complex. The method uses high performance liquid chromatography, and can effectively realize the quality control of products containing traditional Chinese medicine components, and especially stable control of the quality of products containing a large quantity of non-traditional Chinese medicine components in formulas. Through step-by-step quality control, product quality fluctuation is reduced and stable quality is ensured. Meanwhile, the method is simple and convenient, does not need additional instruments and standards, saves the cost and is more conducive to actual production.Type: GrantFiled: April 13, 2020Date of Patent: December 13, 2022Inventors: Shengcan Zou, Li Li, Lei Zong, Jiancheng Zong, Shanglong Wang, Zengliang Zhang
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Patent number: 11517602Abstract: A traditional Chinese medicine composition includes 60%-80% by weight of Eucommia ulmoides extract, 15%-30% by weight of Rhizoma Drynariae extract and 5%-10% by weight of Semen Cuscutae extract. A method of preparing the traditional Chinese medicine composition is also provided. Uses of the traditional Chinese medicine composition in the prevention and/or treatment of osteoporosis are also provided.Type: GrantFiled: September 29, 2020Date of Patent: December 6, 2022Inventors: Shengcan Zou, Zengliang Zhang, Jiancheng Zong, Wenyu Li, Xin Li, Li Li, Shanglong Wang, Lei Zong
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Publication number: 20220326200Abstract: A method for establishing fingerprint of traditional Chinese medicine compound or its preparation with improving cognition is disclosed. By weight, the traditional Chinese medicine compound is made from following raw materials: 1-20 parts of Gastrodiae Rhizoma, 1-15 parts of Polygala tenuifolia, 1-30 parts of Acorus tatarinowii, 0.1-10 parts of Cistanche deserticola Ma, 0.1-10 parts of Rehmanniae Radix Praeparata, and 0.01-1 parts of curcumin. A chromatogram of a test sample solution is established by high performance liquid chromatography. Chromatographic conditions are as follows: a chromatographic column is octadecyl silane bonded silica gel chromatographic column. A column temperature is 25˜35 ° C. A flow rate is 0.9˜ 1.1 ml/min. Detection wavelengths are 210˜230 nm and 310˜330 nm respectively. A mobile phase A is acetonitrile and a mobile phase B is water. And gradient elution is carried out.Type: ApplicationFiled: May 12, 2022Publication date: October 13, 2022Inventors: Shengcan ZOU, Shanglong Wang, Xin Li, Lei Zong, Jiancheng Zong, Zengliang Zhang
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Publication number: 20220274944Abstract: Disclosed are a composite absorbent and a method for using same in the absorption and conversion of ethylene oxide for the coupling co-production of ethylene carbonate. The composite absorbent comprises an ionic liquid and ethylene carbonate, wherein the ionic liquid is an imidazole ionic liquid, a quaternary ammonium ionic liquid and a quaternary phosphonium ionic liquid. The composite absorbent is used for absorbing ethylene oxide and carbon dioxide, and is also used in the absorption and conversion of ethylene oxide for the coupling co-production of ethylene carbonate.Type: ApplicationFiled: March 23, 2020Publication date: September 1, 2022Applicant: Institute of Process Engineering, Chinese Academy of SciencesInventors: Weiguo Cheng, Li Dong, Junjie Chu, Zengliang Zhang, Qian Su, Songsong Chen, Yifan Liu, Xiangping Zhang, Suojiang ZHANG
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Publication number: 20220241362Abstract: A multi-efficacy traditional Chinese medicine compound composition and application thereof in pharmaceutical preparations are disclosed. The traditional Chinese medicine extracts are combined with the glucosamine, the collagen and the chondroitin sulfate, so that the multi-efficacy traditional Chinese medicine compound composition is prepared. The traditional Chinese medicine compound composition starts from improving the health of bone and joint and accompanying cardiovascular disease, selects the medicinal materials, and optimizes the extraction process of the traditional Chinese medicine for the diseases dominated by degenerative osteoarthritis. The disclosure has the efficacious of improving the symptoms of degenerative osteoarthritis, reducing blood pressure, improving the symptoms with osteoporosis, improving the symptoms with cardiovascular disease, improving the symptoms with urinary system disease, etc.Type: ApplicationFiled: March 26, 2021Publication date: August 4, 2022Inventors: Shengcan Zou, Zengliang Zhang, Min Wang, Zhuqing Liu, Sai Lu, Li Li, Shanglong Wang
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Publication number: 20220226413Abstract: The present disclosure relates to the technical field of traditional Chinese medicine, and more specifically, to a traditional Chinese medicine composition with improving cognition effect, its preparation method and a traditional Chinese medicine preparation. In parts by weight, the traditional Chinese medicine composition is made from 1-20 parts of Gastrodiae Rhizoma, 1-15 parts of Polygala tenuifolia Willd., 1-30 parts of Acorus tatarinowii, 0.1-10 parts of Cistanche deserticola Ma, 0.1-10 parts of Rehmanniae Radix Praeparata, and 0.01-1 parts of curcumin. The pharmacodynamic substances of Gastrodiae Rhizoma, Polygala tenuifolia Willd., Acorus tatarinowii, Cistanche deserticola Ma and Rehmanniae Radix Praeparata are extracted completely, concentrated and dried as much as possible. The volatile oil of Acorus tatarinowii and curcumin are encapsulated and dried by the volatile oil encapsulation technology.Type: ApplicationFiled: March 12, 2022Publication date: July 21, 2022Inventors: Shengcan Zou, Shanglong Wang, Xin Li, Lei Zong, Jiancheng Zong, Zengliang Zhang
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Publication number: 20220175865Abstract: A traditional Chinese medicine compound composition with anti-anxiety effect and its preparation method and application are disclosed. The traditional Chinese medicine compound composition with anti-anxiety effect is prepared by compounding the Paeoniae Radix Alba extract, the Gardeniae Fructus extract, the Albiziae Flos extract and the Moutan Cortex extract. The traditional Chinese medicine compound composition has no toxic side effects and has remarkable treatment effect, and can be used as a dietary supplement or a health-care food ingredient to prevent and treat anxiety disorder, and promote mental health. It can be seen that the traditional Chinese medicine compound composition is suitable for promotion and application.Type: ApplicationFiled: May 7, 2021Publication date: June 9, 2022Applicants: Chenland Nutritionals Inc., Qingdao Chenland Pharmaceutical Technology Development Co., Ltd.Inventors: Shengcan Zou, Jiancheng Zong, Wenyu Li, Xin Li, Lei Zong, Zengliang Zhang, Shanglong Wang
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Publication number: 20220160807Abstract: An antidepressant compound preparation and a preparation method for same were disclosed, The antidepressant includes the following raw materials of Hypericum perforatum L., Paeonia lactiflora Pall., Gardenia jasminoides Ellis, Albizia julibrissin Durazz. and Moutan Cortex. The raw materials are weighed in proportion to obtain extracts respectively, and the extracts are mixed to prepare a compound preparation. The compound preparation prepared by the present invention has the advantages of simple preparation, safety, low toxic and side effects, no dependence, etc., and can effectively alleviate depression mood.Type: ApplicationFiled: November 26, 2020Publication date: May 26, 2022Applicants: Qingdao Chenland Pharmaceutical Technology Development Co., Ltd.Inventors: Shengcan Zou, Jiancheng Zong, Wenyu Li, Lei Zong, Zengliang Zhang, Shanglong Wang
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Publication number: 20220152162Abstract: A compound composition for improving bone health and preparation and application thereof are provided. The compound composition is prepared by combining a traditional Chinese medicine extract with chicken cartilage collagen, magnesium, vitamin K2 and vitamin D3. The compound composition overcomes the food safety risk of the existing osteoporosis preventive drugs by adding the traditional Chinese medicine extract for improving osteoporosis and promoting bone health. And the compound composition disclosed can be used as a dietary supplement or health food raw material for preventing or treating osteoporosis. Therefore, the compound composition disclosed is suitable for promotion and application.Type: ApplicationFiled: January 23, 2021Publication date: May 19, 2022Applicants: Chenland Nutritionals Inc., Qingdao Chenland Pharmaceutical Technology Development Co., Ltd.Inventors: Shengcan Zou, Zengliang Zhang, Jiancheng Zong, Wenyu Li, Xin Li, Li Li, Shanglong Wang, Lei Zong
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Patent number: 11331339Abstract: The present invention discloses a compound composition with function of promoting bone and joint health and an application thereof. In the present invention, glucosamine is combined with collagen, chondroitin sulfate and traditional Chinese medicine extract to prepare the compound composition with function of promoting bone and joint health. The compound composition can shorten onset time. At the same time, the traditional Chinese medicine extract for treating the bone and joint problems is added, to reduce the market impact of adding only modern joint health ingredients. Moreover, the compound composition disclosed by the present invention can be used as a dietary supplement or health food raw material for preventing or treating moderate to mild osteoarthritis. Thus, the compound composition disclosed by the present invention is suitable for promotion and application.Type: GrantFiled: April 13, 2020Date of Patent: May 17, 2022Inventors: Shengcan Zou, Li Li, Lei Zong, Jiancheng Zong, Shanglong Wang, Zengliang Zhang
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Publication number: 20220087926Abstract: A compound composition with anti-oxidation and anti-aging effects and preparation method and application thereof we disclosed. 5-8 kinds of traditional Chinese medicine extracts from separate extraction of Panax ginseng C. A. Meyer, Poria, Rehmannia glutinosa, Cistanche deserticola Ma, Salviae Miltiorrhizae, Codonopsis Radix, Persicae Semen and Ophiopogon japonicus (Linn.f.) Ker-Gawl. are compounded with chitooligosaccharide to prepare the compound composition with anti-oxidation and anti-aging effects. The compound composition has no toxic side effects, is easy to be absorbed, and can be used for delaying aging, repairing DNA damage and anti-oxidation damage, and can also reduce the risk of geriatric diseases. Moreover, the compound composition can be used as a raw material of dietary supplement or health food to improve telomerase content and delay aging. Therefore, the compound composition is suitable for promotion and application.Type: ApplicationFiled: March 22, 2021Publication date: March 24, 2022Inventors: Shengcan Zou, Zengliang Zhang, Min Wang, Sai Lu, Zhuqing Liu, Jiancheng Zong, Shanglong Wang
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Publication number: 20210325356Abstract: The present invention relates to the field of analysis of traditional Chinese medicine, and in particular to a method of establishing a fingerprint spectrum of a traditional Chinese medicine composition with effect of regulating depression emotion or a formulation thereof, wherein the traditional Chinese medicine composition consists of the following traditional Chinese medicine extracts in parts by weight: 40˜80 parts of Hypericum perforatum extract, 10˜40 parts of Acanthopanax senticosus extract, and 2˜20 parts of tree peony root bark extract; and the method comprises establishing the fingerprint spectrum by high performance liquid chromatography, and the chromatographic conditions are as follows: an octadecylsilane bonded silica gel chromatographic column is used as a chromatographic column; column temperature is 25˜35° C.; flow rate is 0.5˜1.Type: ApplicationFiled: December 20, 2019Publication date: October 21, 2021Applicant: CHENLAND NUTRITIONALS, INC.Inventors: Shengcan ZOU, Zengliang ZHANG, Wenyu LI, Shanglong WANG, Lei ZONG, Jiancheng ZONG
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Publication number: 20210109068Abstract: The present invention discloses a fingerprint detection method for an antidepressant drug, which adopts liquid chromatography to characterize pharmacological active ingredients of the antidepressant drug composed of Hypericum perforatum L., Paeonia lactiflora Pall, Gardenia jasminoides Ellis, Albizia julibrissin Durazz, and Moutan Cortex, provides an effective detection method, and realizes the quality control of traditional Chinese medicine compositions. The fingerprint detection method provided by the present invention has the advantages of high repeatability and high stability.Type: ApplicationFiled: November 11, 2020Publication date: April 15, 2021Inventors: Shengcan Zou, Jiancheng Zong, Wenyu Li, Lei Zong, Zengliang Zhang, Shanglong Wang
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Publication number: 20210069275Abstract: A traditional Chinese medicine composition includes 60%-80% by weight of Eucommia ulmoides extract, 15%-30% by weight of Rhizoma Drynariae extract and 5%-10% by weight of Semen Cuscutae extract. A method of preparing the traditional Chinese medicine composition is also provided. Uses of the traditional Chinese medicine composition in the prevention and/or treatment of osteoporosis are also provided.Type: ApplicationFiled: September 29, 2020Publication date: March 11, 2021Inventors: Shengcan Zou, Zengliang Zhang, Jiancheng Zong, Wenyu LI, Xin LI, Li Li, Shanglong Wang, Lei Zong
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Publication number: 20200240967Abstract: The present invention discloses a method for product quality control and fingerprint detection of an epimedium brevicornu complex. The method uses high performance liquid chromatography, and can effectively realize the quality control of products containing traditional Chinese medicine components, and especially stable control of the quality of products containing a large quantity of non-traditional Chinese medicine components in formulas. Through step-by-step quality control, product quality fluctuation is reduced and stable quality is ensured. Meanwhile, the method is simple and convenient, does not need additional instruments and standards, saves the cost and is more conducive to actual production.Type: ApplicationFiled: April 13, 2020Publication date: July 30, 2020Inventors: Shengcan Zou, Li Li, Lei Zong, Jiancheng Zong, Shanglong Wang, Zengliang Zhang
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Publication number: 20200237805Abstract: The present invention discloses a compound composition with function of promoting bone and joint health and an application thereof. In the present invention, glucosamine is combined with collagen, chondroitin sulfate and traditional Chinese medicine extract to prepare the compound composition with function of promoting bone and joint health. The compound composition can shorten onset time. At the same time, the traditional Chinese medicine extract for treating the bone and joint problems is added, to reduce the market impact of adding only modern joint health ingredients. Moreover, the compound composition disclosed by the present invention can be used as a dietary supplement or health food raw material for preventing or treating moderate to mild osteoarthritis. Thus, the compound composition disclosed by the present invention is suitable for promotion and application.Type: ApplicationFiled: April 13, 2020Publication date: July 30, 2020Inventors: Shengcan Zou, Li Li, Lei Zong, Jiancheng Zong, Shanglong Wang, Zengliang Zhang