Patents by Inventor Zengming Yang

Zengming Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Veterinary pharmaceutical formulation containing avian embryonic stem cells
    Patent number: 5830510
    Abstract: A method of producing undifferentiated avian cells expressing an embryonic stem cell phenotype is disclosed. The method comprises collecting avian cells from an avian blastoderm prior to formation of the primitive streak, then depositing the avian cells in contact with a mouse fibroblast feeder cell layer, and then growing the avian cells on the mouse fibroblast feeder cell layer in the presence of a media containing leukemia inhibitory factor in a differentiation-inhibiting amount for a time sufficient to produce a sustained avian cell culture. Cell cultures produced by the aforesaid process and veterinary pharmaceutical formulations containing such cells are also disclosed.
    Type: Grant
    Filed: March 26, 1997
    Date of Patent: November 3, 1998
    Assignee: North Carolina State University
    Inventors: James N. Petitte, Zengming Yang
  • Avian embryonic stem cells
    Patent number: 5656479
    Abstract: A method of producing undifferentiated avian cells expressing an embryonic stem cell phenotype is disclosed. The method comprises collecting avian cells from an avian blastoderm prior to formation of the primitive streak, then depositing the avian cells in contact with a mouse fibroblast feeder cell layer, and then growing the avian cells on the mouse fibroblast feeder cell layer in the presence of a media containing leukemia inhibitory factor in a differentiation-inhibiting amount for a time sufficient to produce a sustained avian cell culture. Cell cultures produced by the aforesaid process and veterinary pharmaceutical formulations containing such cells are also disclosed.
    Type: Grant
    Filed: May 20, 1994
    Date of Patent: August 12, 1997
    Assignee: North Carolina State University
    Inventors: James N. Petitte, Zengming Yang
  • Method of producing an avian embryonic stem cell culture and the avian embryonic stem cell culture produced by the process
    Patent number: 5340740
    Abstract: A method of producing undifferentiated avian cells expressing an embryonic stem cell phenotype is disclosed. The method comprises collecting avian cells from an avian blastoderm prior to formation of the primitive streak, then depositing the avian cells in contact with a mouse fibroblast feeder cell layer, and then growing the avian cells on the mouse fibroblast feeder cell layer in the presence of a media containing leukemia inhibitory factor in a differentiation-inhibiting amount for a time sufficient to produce a sustained avian cell culture. Cell cultures produced by the aforesaid process and veterinary pharmaceutical formulations containing such cells are also disclosed.
    Type: Grant
    Filed: May 15, 1992
    Date of Patent: August 23, 1994
    Assignee: North Carolina State University
    Inventors: James N. Petitte, Zengming Yang