Patents by Inventor Zengru Wu

Zengru Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IDENTIFICATION AND QUANTITATION OF INSULIN-LIKE GROWTH FACTOR-I VARIANTS BY MASS SPECTROMETRY
    Publication number: 20250155448
    Abstract: A method for detecting insulin-like growth factor-I (IGF-I) variant(s) in a sample includes purifying the sample using solid phase extraction, ionizing IGF-I in the purified sample to produce one or more ions detectable by mass spectrometry, detecting one or more of the ions comprising an ion with a mass-to-charge ratio selected from the group consisting of 1093.5±0.5, 1089.8±0.5, 1095±0.5, 1097.09±0.5, and 1098.09±0.5 by mass spectrometry, and using the detected ion or ions to determine the presence of IGF-I variant(s) in the sample.
    Type: Application
    Filed: January 2, 2025
    Publication date: May 15, 2025
    Inventors: Ievgen Motorykin, Nigel Clarke, Michael J. McPhaul, Zengru Wu
  • Identification and quantitation of insulin-like growth factor-I variants by mass spectrometry
    Patent number: 12222354
    Abstract: Methods are provided for detecting insulin-like growth factor-I (IGF-I) variant(s) in a sample. Methods provided herein are further directed to using the detected ion or ions to determine the presence of IGF1 variant(s) in the sample.
    Type: Grant
    Filed: March 17, 2022
    Date of Patent: February 11, 2025
    Assignee: Quest Diagnostics Investments LLC
    Inventors: Ievgen Motorykin, Nigel Clarke, Michael J. McPhaul, Zengru Wu
  • IDENTIFICATION AND QUANTITATION OF INSULIN-LIKE GROWTH FACTOR-I VARIANTS BY MASS SPECTROMETRY
    Publication number: 20220299524
    Abstract: Methods are provided for detecting insulin-like growth factor-I (IGF-I) variant(s) in a sample. Methods provided herein are further directed to using the detected ion or ions to determine the presence of IGF1 variant(s) in the sample.
    Type: Application
    Filed: March 17, 2022
    Publication date: September 22, 2022
    Applicant: Quest Diagnostics Investments LLC
    Inventors: Ievgen Motorykin, Nigel Clarke, Michael J. McPhaul, Zengru Wu