Patents by Inventor Zer-Ran Yu

Zer-Ran Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190022590
    Abstract: The present invention provides a device for separating and purifying the collagen Type 2 in chicken bones, comprising a liquid fluid container, a raw liquid container, a membrane separation tank, a mixing tube, two high pressure metering motors, a precooler, two preheaters, a temperature controller, two one-way valves, two inlet control valves and two outlet control valves. The liquid extract of defatted chicken bones discharged from the raw liquid container and the liquid CO2 discharged from the liquid fluid container can be mixed uniformly in the mixing tube, and then fed into the membrane separation tank. The membrane separation tank produces small-molecular-weight peptides and large-molecular-weight collagen Type 2 harmlessly and efficiently.
    Type: Application
    Filed: October 5, 2017
    Publication date: January 24, 2019
    Inventors: Zer-Ran Yu, Hui-Chen Kuo, Be-Jen Wang, Po-Wen Yu, Hui-Chen Chung, Shu-Mei Lin, Kuo-Chuan Chen, Tsai-Jen Hung
  • Patent number: 9567365
    Abstract: The present invention provides a method of separating estrogen from placenta, which uses supercritical fluid technique to load the placenta powder of human body or sheep, pig, deer and other animals into an extraction tank. Under the operating conditions of preset pressure and temperature, supercritical solvent is added into the extraction tank to extract estrogen from placenta, so as to acquire de-estrogen placenta powder and placenta extract liquor. Under the same condition, the de-estrogen placenta extract liquor and supercritical solvent are added by a preset volume flow ratio into an adsorption tank. The estrogen in the placenta extract liquor is adsorbed by the adsorption tank to obtain de-estrogen placenta extract. It is then eluted with ethanol solution by gradient proportion to obtain purified natural estrogen.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: February 14, 2017
    Assignees: SUPER WELL BIOTECHNOLOGY CORPORATION, ULTRA-MICRORIGIN BIOMEDICAL TECHNOLOGY CO., LTD.
    Inventors: Zer-Ran Yu, Be-Jen Wang, Shu-Mei Lin, Hua-Ching Lin, Ming-Hsi Chuang, Chu-Ting Liu, Chiu-Ying Peng, Lin-Hsiang Chuang
  • Publication number: 20160159847
    Abstract: The present invention provides a method of separating estrogen from placenta, which uses supercritical fluid technique to load the placenta powder of human body or sheep, pig, deer and other animals into an extraction tank. Under the operating conditions of preset pressure and temperature, supercritical solvent is added into the extraction tank to extract estrogen from placenta, so as to acquire de-estrogen placenta powder and placenta extract liquor. Under the same condition, the de-estrogen placenta extract liquor and supercritical solvent are added by a preset volume flow ratio into an adsorption tank. The estrogen in the placenta extract liquor is adsorbed by the adsorption tank to obtain de-estrogen placenta extract. It is then eluted with ethanol solution by gradient proportion to obtain purified natural estrogen.
    Type: Application
    Filed: February 9, 2016
    Publication date: June 9, 2016
    Inventors: Zer-Ran YU, Be-Jen WANG, Shu-Mei LIN, Hua-Ching LIN, Ming-Hsi CHUANG, Chu-Ting LIU, Chiu-Ying PENG, Lin-Hsiang CHUANG
  • Publication number: 20160074773
    Abstract: The present invention provides a method to separate and purify functional ingredients in placenta using supercritical fluid technology, where, placenta extract liquid and supercritical CO2 solvent are guided into a fractionation tank constantly in a preset velocity at a preset temperature and pressure to extract peptides, proteins and other functional ingredients. And then, the solution is conveyed through the three fractionation tanks at a preset temperature and depressurized gradually to separate, fractionate and purify the content of placenta peptide and protein, so as to obtain the high purity of peptides, proteins, active factors and other functional ingredients.
    Type: Application
    Filed: May 1, 2015
    Publication date: March 17, 2016
    Inventors: Zer-Ran YU, Be-Jen WANG, Shu-Mei LIN, Hua-Ching LIN, Ming-Hsi CHUANG, Chu-Ting LIU, I-Lung YU, Chiu-Ying PENG, Lin-Hsiang CHUANG
  • Publication number: 20160051591
    Abstract: The present invention provides a method for the separation of placenta functional ingredients. By using the supercritical fluid technology, the placenta powder is placed inside an extraction tank, under the predetermined pressure and temperature; the supercritical CO2 solvent is flown into the adsorption tank, in order to deodorize the fishy smell of the placenta powder, and extract the oil of the placenta powder. Under the same operating conditions as mentioned above, the deodorized and extracted placenta powder and supercritical CO2/ethanol solvents are flown into an adsorption tank at the predetermined volumetric flow rate ratio to adsorb the estrogen of placenta powder to get the estrogen-removed placenta peptide extracts. Afterwards, supercritical CO2/ethanol solvents are separated by rapid decompression to get the functional ingredients of placenta powder.
    Type: Application
    Filed: May 1, 2015
    Publication date: February 25, 2016
    Inventors: Zer-Ran YU, Be-Jen WANG, Tsao-Chen WEI, Hua-Ching LIN, Ming-Hsi CHUANG, Chu-Ting LIU, I-Lung YU, Chiu-Ying PENG, Lin-Hsiang CHUANG
  • Patent number: 9266920
    Abstract: The present invention provides a preparation method of deglycosylated ginsenosides, which uses the supercritical fluid technology to conduct the deglycosylation of ginsenosides extract in supercritical solvent under preset pressure and temperature conditions. Under the same operational conditions, the deglycosylated ginsenosides extract and solvent at supercritical state are input into an adsorption tank at the preset volume flow rate ratio for the adsorption of ginsenosides. Then, the adsorbed ginsenosides are applied with gradient eluent by using the ethanol solution. Finally, the pressure is lowered for the separation and purification of ginsenosides to get the deglycosylated ginsenosides of high concentration.
    Type: Grant
    Filed: January 9, 2014
    Date of Patent: February 23, 2016
    Inventors: Zer-Ran Yu, Shuen-An Kang
  • Publication number: 20150274769
    Abstract: The present invention provides a method of separating estrogen from placenta, which uses supercritical fluid technique to load the placenta powder of human body or sheep, pig, deer and other animals into an extraction tank. Under the operating conditions of preset pressure and temperature, supercritical solvent is added into the extraction tank to extract estrogen from placenta, so as to acquire de-estrogen placenta powder and placenta extract liquor. Under the same condition, the de-estrogen placenta extract liquor and supercritical solvent are added by a preset volume flow ratio into an adsorption tank. The estrogen in the placenta extract liquor is adsorbed by the adsorption tank to obtain de-estrogen placenta extract. It is then eluted with ethanol solution by gradient proportion to obtain purified natural estrogen.
    Type: Application
    Filed: June 10, 2014
    Publication date: October 1, 2015
    Inventors: Zer-Ran YU, Be-Jen WANG, Shu-Mei LIN, Hua-Ching LIN, Ming-Hsi CHUANG, Chu-Ting LIU, Chiu-Ying PENG, Lin-Hsiang CHUANG
  • Publication number: 20150191504
    Abstract: The present invention provides a preparation method of deglycosylated ginsenosides, which uses the supercritical fluid technology to conduct the deglycosylation of ginsenosides extract in supercritical solvent under preset pressure and temperature conditions. Under the same operational conditions, the deglycosylated ginsenosides extract and solvent at supercritical state are input into an adsorption tank at the preset volume flow rate ratio for the adsorption of ginsenosides. Then, the adsorbed ginsenosides are applied with gradient eluent by using the ethanol solution. Finally, the pressure is lowered for the separation and purification of ginsenosides to get the deglycosylated ginsenosides of high concentration.
    Type: Application
    Filed: January 9, 2014
    Publication date: July 9, 2015
    Inventors: SHUEN-AN KANG, ZER-RAN YU
  • Publication number: 20140128582
    Abstract: The present invention provides a continuous preparation method of ginseng ginsenosides and polysaccharides, whereby the ginseng extract liquor and supercritical solvent are poured continuously into a separation tank at 10-30 MPa and 40-60° C. as well as a preset flow rate; so the ginseng extract liquor can be separated in the separation tank to obtain ginseng ginsenosides and polysaccharides at different positions of the separation tank.
    Type: Application
    Filed: November 6, 2012
    Publication date: May 8, 2014
    Inventors: Zer-Ran Yu, Be-Jen Wang
  • Publication number: 20130287927
    Abstract: The present invention provides a preparation method and system for clarified plum wine and plum extract, blanching plum at 95° C. for 5 minutes, and then extracting the blanched plum with extracting solution containing 70-75% alcohol in volume ratio of 1:2 (w/v) at 8˜10° C. in vacuum for 30 minutes before centrifugation, cooling clarification of the plum juice at ?8° C. and ?20° C. is carried out immediately for 30 minutes respectively, so as to obtain clarified plum wine. Afterwards, the plum wine is concentrated in vacuum to ? of original volume to obtain clarified plum extract; therefore, high quality plum wine and plum extract can be obtained without destroying the plum tissue, and the production efficiency is quite ideal.
    Type: Application
    Filed: April 25, 2012
    Publication date: October 31, 2013
    Inventors: Zer-Ran YU, Be-Jen Wang
  • Publication number: 20130289300
    Abstract: The present invention provides a method and system for separating linalyl acetate from Lavender essential oil and preparing its derivatives, whereby the supercritical fluid technology is used to feed Lavender essential oil and supercritical solvent into the first separating tank, where linalyl acetate and linalool are separated from Lavender essential oil; then linalyl acetate is conveyed to the second separating tank, where linalyl acetate is separated with wax-containing oily substance to obtain high-concentration linalyl acetate; next linalool and vitamin C solution are conveyed to a reaction tank for esterification synthesis, and the reaction tank is filled with acid resin catalyst to obtain linalool-vitamin C derivative; with this design, it is possible to reduce the nervous tension, and adjust high-concentration linalyl acetate affecting physiological and psychological stress, as well as vitamin C derivative with anti-oxidizing oily fragrance.
    Type: Application
    Filed: April 25, 2012
    Publication date: October 31, 2013
    Inventors: Zer-Ran Yu, Be-Jen Wang
  • Publication number: 20130075336
    Abstract: The present invention provides a method and system for continuous separation and purification of ganoderic acids and polysaccharides, which, via the help of supercritical fluid technology, could feed continuously Ganoderma extract and supercritical solvents at a predefined rate into a separator under operating pressure 10-30 MPa and temperature 40-60° C.; then ganoderic acids, polyphenols and polysaccharides can be separated from Ganoderma extract in the separator; with introduction of membrane purification technology, ganoderic acids, polyphenols and polysaccharides are fed continuously to different purifiers to obtain high-purity ganoderic acids, polyphenols and polysaccharides.
    Type: Application
    Filed: September 23, 2011
    Publication date: March 28, 2013
    Inventors: Zer-Ran Yu, Be-Jen Wang
  • Publication number: 20120309947
    Abstract: The present invention provides a method and system for continuous separation and purification of ginsenosides, whereby supercritical fluid technology is used to feed Ginseng extract liquor and supercritical solvent continuously into a separation tank at 20-30 Mpa and 40-60° C.
    Type: Application
    Filed: June 2, 2011
    Publication date: December 6, 2012
    Inventors: Zer-Ran YU, Be-Jen Wang
  • Patent number: 8277855
    Abstract: The present invention provides a method of continuously producing edible lipid-based composition, including the steps: preparing alcohol and organic acid in a predetermined ratio and a reaction tank received with immobilized candida cylindracea; continuously providing a supercritical state solvent into the reaction tank and draining the supercritical state solvent out, and mixing and pressurizing the alcohol and the organic acid and sending the alcohol and the organic acid to the reaction tank for a esterfication of the alcohol and the organic acid by the candida cylindracea; getting an edible lipid-based composition and water in the reaction tank; and quickly separating the edible lipid-based composition from the water and the supercritical state solvent.
    Type: Grant
    Filed: May 7, 2010
    Date of Patent: October 2, 2012
    Inventors: Zer-Ran Yu, Be-Jen Wang
  • Publication number: 20120083592
    Abstract: The present invention provides a continuous preparation method of ginseng ginsenosides and polysaccharides, whereby the ginseng extract liquor and supercritical solvent are poured continuously into a separation tank at 10-30 MPa and 40-60° C. as well as a preset flow rate; so the ginseng extract liquor can be separated in the separation tank to obtain ginsenosides and polysaccharides at different positions of the separation tank.
    Type: Application
    Filed: September 30, 2010
    Publication date: April 5, 2012
    Inventors: Zer-Ran Yu, Be-Jen Wang
  • Publication number: 20110274784
    Abstract: The present invention provides a method of continuously producing edible lipid-based composition, including the steps: preparing alcohol and organic acid in a predetermined ratio and a reaction tank received with immobilized candida cylindracea; continuously providing a supercritical state solvent into the reaction tank and draining the supercritical state solvent out, and mixing and pressurizing the alcohol and the organic acid and sending the alcohol and the organic acid to the reaction tank for a esterfication of the alcohol and the organic acid by the candida cylindracea; getting an edible lipid-based composition and water in the reaction tank; and quickly separating the edible lipid-based composition from the water and the supercritical state solvent.
    Type: Application
    Filed: May 7, 2010
    Publication date: November 10, 2011
    Inventors: Zer-Ran YU, Be-Jen Wang