Abstract: A knob locking assembly for a laparoscopic medical device is provided. The knob locking assembly includes a lock configured to engage the knob locking assembly with a drive tube housing of the laparoscopic medical device in extended and retracted positions where the knob locking assembly rotates but does not translate with respect to the drive tube housing when engaged. The knob locking assembly also has a biasing member that provides a biasing force for biasing the lock in each of the extended and retracted positions to lock out longitudinal translation of the rotatable drive assembly when the knob locking assembly is engaged with the drive tube. In addition, the knob locking assembly includes an actuator to counter the biasing force for disengaging the lock to permit longitudinal translation of the rotatable drive assembly via the knob locking assembly when disengaged.

Abstract: The present disclosure relates generally to systems and methods for screening sample preparation conditions and, more specifically, high throughput screening of tissue sample preparation conditions.

Abstract: A colpotomy device for performing a hysterectomy is provided. The device includes a flexible drive tube having a proximal end and a distal end and bendable therebetween. The device also has a rotatable cutting implement at the distal end of the flexible drive tube at a specified offset from a bendable longitudinal axis of the flexible drive tube. Furthermore, the device includes couplings located within the flexible drive tube and rotatable about the bendable longitudinal axis of the flexible drive tube. The couplings can be in a series that includes inter-coupling joints and transmits a rotational force between the proximal and distal ends of the flexible drive tube through a variable angle between the couplings. The variable angle can correspond to bending of the drive tube in order to drive rotation of the cutting implement at the specified offset about the axis of the flexible drive tube.

Abstract: A knob locking assembly for a laparoscopic medical device is provided. The knob locking assembly includes a lock configured to engage the knob locking assembly with a drive tube housing of the laparoscopic medical device in extended and retracted positions where the knob locking assembly rotates but does not translate with respect to the drive tube housing when engaged. The knob locking assembly also has a biasing member that provides a biasing force for biasing the lock in each of the extended and retracted positions to lock out longitudinal translation of the rotatable drive assembly when the knob locking assembly is engaged with the drive tube. In addition, the knob locking assembly includes an actuator to counter the biasing force for disengaging the lock to permit longitudinal translation of the rotatable drive assembly via the knob locking assembly when disengaged.