Patents by Inventor Zexin Zhou
Zexin Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12226473Abstract: Disclosed are a SARS-COV-2 antigen polypeptide, a recombinant adeno-associated virus (rAAV) expressing the polypeptide, and a vaccine containing the virus. A sequence of the antigen polypeptide is shown in SEQ ID NO: 1 and SEQ ID NO: 2. A method for preparing the recombinant adeno-associated virus comprises co-incubating pHelper, pRep2Cap5, and an expression vector, transfecting a cell in the presence of polyethyleneimine as a transfection reagent; culturing the cell, then collecting the cell by centrifugation, performing lysis and purification to obtain a purified liquid comprising the recombinant adeno-associated virus. The rAAV is delivered and expressed in vivo to produce a fusion antigen polypeptide, induces the production of serum neutralizing antibodies, which have a neutralizing titer to the novel SARS-COV-2 coronavirus and are expressed continuously; the rAAV composition can be used to immunize humans against the novel coronavirus pneumonia COVID-19.Type: GrantFiled: May 24, 2021Date of Patent: February 18, 2025Assignee: Hengda Biomedical Technology Co., Ltd.Inventors: Zexin Zhou, Zhongqiu Liu, Guochao Liao, Huapeng Li, Chao Zhang, Xiaoxiao Qi, Junlin Chen, Deying Yang
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Publication number: 20240216802Abstract: An operation control method and apparatus. The method comprises: acquiring a facial image of a target user; detecting position information of a target part in the facial image; on the basis of the detected position information, and at a relative position, corresponding to the detected position information, on the facial image, displaying a target virtual prop in an initial display form; and adjusting the display form of the target virtual prop according to detected state information of the target part.Type: ApplicationFiled: May 27, 2021Publication date: July 4, 2024Inventors: Hua Zheng, Yandong Cong, Zexin Zhou
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Patent number: 11973340Abstract: A line current iM(k0) of an M side of a first direct-current transmission line is collected at a moment k0. A line current iM(k0?ts) thereof is collected at k0?ts. At a moment k0, a differential value diM(k0) of a current of the side of the first direct-current transmission line is calculated according to the line current iM(k0) and the line current iM(k0?ts). It is determined whether the differential value diM(k0) of the current meets a protection enabling criteria. If so, direct-current protection for the M side of the first direct-current transmission line is enabled. A line current iM(j) of the M side of the first direct-current transmission line is collected at a moment j. A line current iM(j?ts) thereof is collected at a moment j?ts. A differential value diM(j) of the current of the M side of the first direct-current transmission line at the moment j is calculated according to the line current iM(j) and the line current iM(j?ts).Type: GrantFiled: June 18, 2020Date of Patent: April 30, 2024Assignees: CHINA ELECTRIC POWER RESEARCH INSTITUTE, STATE GRID CORPORATION OF CHINAInventors: Zexin Zhou, Huanzhang Liu, Pengfei Lv, Hong Cao, Xingguo Wang, Siye Ruan, Dingxiang Du, Yong Li, Guosheng Yang, Mingliang Jin
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Patent number: 11749985Abstract: A method and device for timing in time-varying distance protection based on multiple lines of a tower. The method includes: collecting an instantaneous current value at a time-varying distance protection installation location in the multiple lines of the tower, and acquiring preset parameters; calculating, according to the preset parameters and a multi-line ranging model, a multi-line ranging result; calculating, according to the preset parameters, the multi-line ranging result, and an adaptive calculation model, time of a section-II distance protection action and final time of a section-III distance protection action; and determining, according to the instantaneous current value, the preset parameters, and a cross-line failure auxiliary criterion model, final time of the section-II distance protection action.Type: GrantFiled: October 31, 2019Date of Patent: September 5, 2023Assignees: CHINA ELECTRIC POWER RESEARCH INSTITUTE, STATE GRID CORPORATION OF CHINAInventors: Zexin Zhou, Tianhua Li, Hong Cao, Yarong Guo, Xingguo Wang, Dingxiang Du, Delin Wang, Pengfei Lv, Zhi Zhang
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Patent number: 11742652Abstract: A method and device for starting direct-current (DC) transmission line protection, and a storage medium. The method includes: determining whether a sudden change of a DC line current at a present moment is greater than a sum of a memory start threshold and a maximum value in sudden changes of the DC line current within a time period preceding the present moment that is multiplied by a preset proportional coefficient, the time period being a time period between a moment preceding the present moment by a first duration and a moment preceding the present moment by a second duration; and starting DC transmission line protection in response to determining that the sudden change of the DC line current at the present moment is greater than the sum.Type: GrantFiled: August 13, 2019Date of Patent: August 29, 2023Assignees: CHINA ELECTRIC POWER RESEARCH INSTITUTE, STATE GRID CORPORATION OF CHINAInventors: Hong Cao, Zexin Zhou, Huanzhang Liu, Dingxiang Du, Xingguo Wang
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Publication number: 20220413031Abstract: A line double-end steady-state quantity distance measuring method and system based on an amplitude-comparison principle. According to the method and system, voltage values and current values of both sides of a line before and after a fault are collected (102), a voltage variable quantity and a current variable quantity of both sides of the line are calculated (103), and after a voltage phasor value and a current phasor value are determined according to the voltage variable quantity and the current variable quantity (104), the position of a short-circuit point is determined by performing iterative calculation on the voltage of the short-circuit point. The method is simple in principle, and can accurately recognize a fault point, achieving precise distance measurement of lines.Type: ApplicationFiled: July 8, 2020Publication date: December 29, 2022Inventors: Yarong GUO, Xingguo WANG, Zexin ZHOU, Ying LIANG, Guosheng YANG, Huanzhang LIU, Dingxiang DU, Yong LI, Shuyang WANG, Qi CHENG, Hong CAO, Zhengguang CHEN
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Publication number: 20220285931Abstract: Disclosed are a direct-current transmission line protection method and system based on pure current characteristics.Type: ApplicationFiled: June 18, 2020Publication date: September 8, 2022Applicants: CHINA ELECTRIC POWER RESEARCH INSTITUTE, STATE GRID CORPORATION OF CHINAInventors: Zexin ZHOU, Huanzhang LIU, Pengfei LV, Hong CAO, Xingguo WANG, Siye RUAN, Dingxiang DU, Yong LI, Guosheng YANG, Mingliang JIN
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Publication number: 20220239093Abstract: A method and device for timing in time-varying distance protection based on multiple lines of a tower. The method includes: collecting an instantaneous current value at a time-varying distance protection installation location in the multiple lines of the tower, and acquiring preset parameters; calculating, according to the preset parameters and a multi-line ranging model, a multi-line ranging result; calculating, according to the preset parameters, the multi-line ranging result, and an adaptive calculation model, time of a section-II distance protection action and final time of a section-III distance protection action; and determining, according to the instantaneous current value, the preset parameters, and a cross-line failure auxiliary criterion model, final time of the section-II distance protection action.Type: ApplicationFiled: October 31, 2019Publication date: July 28, 2022Applicants: CHINA ELECTRIC POWER RESEARCH INSTITUTE, STATE GRID CORPORATION OF CHINAInventors: Zexin ZHOU, Tianhua LI, Hong CAO, Yarong GUO, Xingguo WANG, Dingxiang DU, Delin WANG, Pengfei LV, Zhi ZHANG
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Publication number: 20220131367Abstract: A method and device for starting direct-current (DC) transmission line protection, and a storage medium. The method includes: determining whether a sudden change of a DC line current at a present moment is greater than a sum of a memory start threshold and a maximum value in sudden changes of the DC line current within a time period preceding the present moment that is multiplied by a preset proportional coefficient, the time period being a time period between a moment preceding the present moment by a first duration and a moment preceding the present moment by a second duration; and starting DC transmission line protection in response to determining that the sudden change of the DC line current at the present moment is greater than the sum.Type: ApplicationFiled: August 13, 2019Publication date: April 28, 2022Inventors: Hong CAO, Zexin ZHOU, Huanzhang LIU, Dingxiang DU, Xingguo WANG
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Publication number: 20210346493Abstract: Disclosed are a SARS-COV-2 antigen polypeptide, a recombinant adeno-associated virus (rAAV) expressing the polypeptide, and a vaccine containing the virus. A sequence of the antigen polypeptide is shown in SEQ NO. 1. and SEQ ID NO. 2. A method for preparing the recombinant adeno-associated virus comprises co-incubating pHelper, pRep2Cap5, and an expression vector, transfecting a cell in the presence of polyethyleneimine as a transfection reagent; culturing the cell, then collecting the cell by centrifugation, performing lysis and purification to obtain a purified liquid comprising the recombinant adeno-associated virus. The rAAV is delivered and expressed in vivo to produce a fusion antigen polypeptide, induces the production of serum neutralizing antibodies, which have a neutralizing titer to the novel SARS-COV-2 coronavirus and are expressed continuously; the rAAV composition can be used to immunize humans against the novel coronavirus pneumonia COVID-19.Type: ApplicationFiled: May 24, 2021Publication date: November 11, 2021Inventors: Zexin Zhou, Zhongqiu Liu, Guochao Liao, Huapeng Li, Chao Zhang, Xiaoxiao Qi, Junlin Chen, Deying Yang
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Patent number: 10985547Abstract: A current differential protection method for a self-adaptive half-wavelength line based on a time-difference method. Since an electrical distance of half-wavelength power transmission is long, after a fault occurs, there is an obvious time difference between the actuation times for protecting starting elements at two sides of a line. According to the principles of wave propagation, the position of a fault point can be determined by means of a difference between the actuation times for protecting the starting elements at the two sides of the line. By means of taking the fault point as a differential point, a current value at the differential point can be obtained according to a long line equation by means of the voltage and current at protection-mounted positions at the two sides of the line, and a differential current is then calculated.Type: GrantFiled: July 11, 2016Date of Patent: April 20, 2021Assignees: CHINA ELECTRIC POWER RESEARCH INSTITUTE COMPANY LIMITED, STATE GRID CORPORATION OF CHINA, CENTRAL CHINA BRANCH OF STATE GRID CORPORATION OF CHINAInventors: Xuming Liang, Yarong Guo, Huanzhang Liu, Xiao Li, Zexin Zhou, Dingxiang Du, Delin Wang, Jing Li, Huixin Li, Zhongqing Li
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Patent number: 10778003Abstract: A method of free wave energy protection for a half-wavelength line based on a one-sided current includes: performing sampling and calculation on a current at protection measuring points to obtain variations in current sampling values; and activating a protective element to determine an occurrence time of a fault in a half-wavelength line. A free wave energy protection section includes a quick-action section, a basic section and a sensitive section, wherein the quick-action section, the basic section and the sensitive section serve as action criteria for performing protection with respect to the free wave energy of the half-wavelength line.Type: GrantFiled: July 18, 2016Date of Patent: September 15, 2020Assignees: CHINA ELECTRIC POWER RESEARCH INST. CO. LIMITED, STATE GRID CORPORATION OF CHINA, STATE GRID CENTRAL CHINA GRID COMPANY LTD.Inventors: Huanzhang Liu, Zexin Zhou, Dingxiang Du, Yarong Guo, Xiao Li, Xuming Liang, Delin Wang, Xingguo Wang
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Patent number: 10605852Abstract: A concomitant impedance protection method for a half-wavelength power transmission line includes that: three-phase currents and three-phase voltages of a relay protection device mounting position at an M side and a relay protection device mounting position at an N side of the half-wavelength power transmission line are acquired respectively; it is judged whether starting amounts of an M side and an N side meet starting conditions or not; a failure point F is determined according to a time difference when the starting amounts of the M side and the N side meet the starting conditions; and a relay protection action of the half-wavelength power transmission line is started according to concomitant impedance of the half-wavelength power transmission line.Type: GrantFiled: June 30, 2016Date of Patent: March 31, 2020Assignees: CHINA ELECTRIC POWER RESEARCH INSTITUTE COMPANY LIMITED, STATE GRID CORPORATION OF CHINA, CENTRAL CHINA BRANCH OF STATE GRID CORPORATION OF CHINAInventors: Dingxiang Du, Huanzhang Liu, Zexin Zhou, Xuming Liang, Yarong Guo, Xingguo Wang, Lianhai Li, Delin Wang, Xiao Li, Xiangwen Chen
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Publication number: 20190013667Abstract: A method of free wave energy protection for a half-wavelength line based on a one-sided current includes: performing sampling and calculation on a current at protection measuring points to obtain variations in current sampling values; and activating a protective element to determine an occurrence time of a fault in a half-wavelength line. A free wave energy protection section includes a quick-action section, a basic section and a sensitive section, wherein the quick-action section, the basic section and the sensitive section serve as action criteria for performing protection with respect to the free wave energy of the half-wavelength line.Type: ApplicationFiled: July 18, 2016Publication date: January 10, 2019Inventors: Huanzhang Liu, Zexin Zhou, Dingxiang Du, Yarong Guo, Xiao Li, Xuming Liang, Delin Wang, Xingguo Wang
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Publication number: 20180375322Abstract: A current differential protection method for a self-adaptive half-wavelength line based on a time-difference method. Since an electrical distance of half-wavelength power transmission is long, after a fault occurs, there is an obvious time difference between the actuation times for protecting starting elements at two sides of a line. According to the principles of wave propagation, the position of a fault point can be determined by means of a difference between the actuation times for protecting the starting elements at the two sides of the line. By means of taking the fault point as a differential point, a current value at the differential point can be obtained according to a long line equation by means of the voltage and current at protection-mounted positions at the two sides of the line, and a differential current is then calculated.Type: ApplicationFiled: July 11, 2016Publication date: December 27, 2018Inventors: Xuming LIANG, Yarong GUO, Huanzhang LIU, Xiao LI, Zexin ZHOU, Dingxiang DU, Delin WANG, Jing LI, Huixin LI, Zhongqing LI
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Publication number: 20180364292Abstract: A concomitant impedance protection method for a half-wavelength power transmission line includes that: three-phase currents and three-phase voltages of a relay protection device mounting position at an M side and a relay protection device mounting position at an N side of the half-wavelength power transmission line are acquired respectively; it is judged whether starting amounts of an M side and an N side meet starting conditions or not; a failure point F is determined according to a time difference when the starting amounts of the M side and the N side meet the starting conditions; and a relay protection action of the half-wavelength power transmission line is started according to concomitant impedance of the half-wavelength power transmission line.Type: ApplicationFiled: June 30, 2016Publication date: December 20, 2018Applicants: CHINA ELECTRIC POWER RESEARCH INSTITUTE COMPANY LIMITED, STATE GRID CORPORATION OF CHINA, CENTRAL CHINA BRANCH OF STATE GRID CORPORATION OF CHINAInventors: Dingxiang Du, Huanzhang Liu, Zexin Zhou, Xuming Liang, Yarong Guo, Xingguo Wang, Lianhai Li, Delin Wang, Xiao Li, Xiangwen Chen
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Publication number: 20170317489Abstract: The invention provides a method for overcoming the influence of out-flowing current on bus differential protection. The method comprises the following steps: acquiring and processing branch current signals; selecting a fault bus, and determining the branch current with maximum amplitude from branches connected with the fault bus; calculating differential current and restraint current of a large differential element, and determining whether the large differential element acts. The method for overcoming the influence of out-flowing current on bus differential protection does not need to reduce the braking coefficient during splitting operation in a two-bus connecting mode, can adaptively improve the sensitivity of bus differential protection under an internal fault in the presence of out-flowing current, and simultaneously ensures the reliability under an external fault.Type: ApplicationFiled: August 24, 2015Publication date: November 2, 2017Applicants: STATE GRID CORPORATION OF CHINA, CHINA ELECTRIC POWER RESEARCH INSTITUTE, CENTER CHINA GRID COMPANY LIMITEDInventors: Dingxiang DU, Huanzhang LIU, Zexin ZHOU, Xingguo WANG
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Patent number: 8740227Abstract: The present invention discloses a self-locking mechanism for use in a drill chuck, comprising: clutch tooth sleeves, fixedly connected with the chuck body of the drill chuck and forming teeth; an oval deformation ring, having a substantially circular first shape and a substantially oval second shape, wherein the oval deformation ring has teeth on the side wall, with the teeth engaging with the teeth of the clutch tooth sleeve when the oval deformation ring is in the second shape; and a control sleeve, for controlling the conversion of the oval deformation sleeve between the first shape and the second shape. The present invention also discloses a force increasing self-locking drill chuck with said self-locking mechanism. The self-locking mechanism according to the present invention can be used in drill chucks of multiple structures, and provides a brand-new thought for the designs of the self-locking mechanisms of drill chucks.Type: GrantFiled: January 19, 2010Date of Patent: June 3, 2014Assignee: Shandong Weida Machinery Co., Ltd.Inventors: Zexin Zhou, Guijie Li
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Patent number: 7896356Abstract: The present invention discloses a chuck mounted on a transmission shaft driven by a power source, and the chuck comprises a chuck body, plural jaws, a rear cap, an outer sleeve rotatablely fitted around the chuck body and located in front of the rear cap, and a transmission nut, characterized in that the chuck further comprises a drive pendulum support sleeve which is located between the outer sleeve and the transmission nut, connected with the outer sleeve and fitted around the chuck body; and a drive pendulum which is mounted on the drive pendulum support sleeve, swings between a first and second positions about its pivot axis, and has first and second drive portions, wherein the drive pendulum drives the transmission nut along a first transmission path through the first drive portion when it is in the first position, and drives the transmission nut along a second transmission path of more gripping force than the first transmission path through the second drive portion when it is in the second position.Type: GrantFiled: April 5, 2007Date of Patent: March 1, 2011Assignee: Shandong Weida Machinery Co., Ltd.Inventors: Zexin Zhou, Guijie Li
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Publication number: 20100181735Abstract: The present invention discloses a self-locking mechanism for use in a drill chuck, comprising: clutch tooth sleeves, fixedly connected with the chuck body of the drill chuck and forming teeth; an oval deformation ring, having a substantially circular first shape and a substantially oval second shape, wherein the oval deformation ring has teeth on the side wall, with the teeth engaging with the teeth of the clutch tooth sleeve when the oval deformation ring is in the second shape; and a control sleeve, for controlling the conversion of the oval deformation sleeve between the first shape and the second shape. The present invention also discloses a force increasing self-locking drill chuck with said self-locking mechanism. The self-locking mechanism according to the present invention can be used in drill chucks of multiple structures, and provides a brand-new thought for the designs of the self-locking mechanisms of drill chucks.Type: ApplicationFiled: January 19, 2010Publication date: July 22, 2010Inventors: Zexin Zhou, Li Guijie