Patents by Inventor Zeynep (Yesim) Kucuk

Zeynep (Yesim) Kucuk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for suppressing allergic reactions
    Patent number: 9868786
    Abstract: Provided are methods for suppressing IgE and IgG-mediated allergic reactions through monoclonal antibody applications. More specifically, methods are herein provided for safe induction of rapid desensitization. Specific embodiments are herein provided for suppressing allergic reactions in a subject, including specific methods of providing a monoclonal antibody selected from the group consisting of anti-Fc?RIa and anti-Fc?RIIb / RIII; administering the antibody to a subject at a dose that is lower than the level required to induce shock; and administering sequentially escalating doses of the monoclonal antibody so as to induce rapid desensitization to an allergen, thereby suppressing allergic reaction in the subject.
    Type: Grant
    Filed: April 12, 2012
    Date of Patent: January 16, 2018
    Assignees: University of Cincinnati, Children's Hospital Medical Center, U.S. Department of Veterans Affairs, Medizinische Universität Wien
    Inventors: Fred D. Finkelman, Marat V. Khodoun, Durga Krishnamurthy, Richard T. Strait, Zeynep (Yesim) Kucuk
  • METHODS FOR SUPPRESSING ALLERGIC REACTIONS
    Publication number: 20140314783
    Abstract: Provided are methods for suppressing IgE and IgG-mediated allergic reactions through monoclonal antibody applications. More specifically, methods are herein provided for safe induction of rapid desensitization. Specific embodiments are herein provided for suppressing allergic reactions in a subject, including specific methods of providing a monoclonal antibody selected from the group consisting of anti-Fc?RIa and anti-Fc?RIIb/RIII; administering the antibody to a subject at a dose that is lower than the level required to induce shock; and administering sequentially escalating doses of the monoclonal antibody so as to induce rapid desensitization to an allergen, thereby suppressing allergic reaction in the subject.
    Type: Application
    Filed: April 12, 2012
    Publication date: October 23, 2014
    Inventors: Fred D. Finkelman, Marat V. Khodoun, Durga Krishnamurthy, Richard T. Strait, Zeynep (Yesim) Kucuk