Abstract: A boundary adaptive structural fatigue damage detection method driven by time-domain information entropy comprises a sensor sequence composed of several sensors arranged on the structure, which is used to apply excitation to the structure, collect the displacement time-history response curves at different positions on the structure, and establish a database of time-history data. According to the data set in the database, the information entropy of the time-history response at different positions on the acquisition structure is obtained based on the information entropy to measure the disorder degree of the time-domain response signal. According to the location of several sensors, the information entropy values of the time-history response are connected in turn to obtain the time-history information entropy curve of the whole structure. Analyze of time-history information entropy curve, and the information entropy curve will show jump phenomena to determine the location of the crack.