Patents by Inventor Zhan-Gong Zhao

Zhan-Gong Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200016567
    Abstract: The manufacturing of molecular arrays often requires the coordination of various physical, chemical, and thermal parameters. Hence, the quality and homogeneity of many molecular arrays can be very dependent on the method of manufacturing. The instant disclosure provides a device that is configured to consistently yield peptide arrays of high quality. The device distributes optimum levels of heat and coupling solution during the chemical coupling and manufacturing of peptide array.
    Type: Application
    Filed: March 13, 2018
    Publication date: January 16, 2020
    Inventors: Neal Woodbury, Zhan-Gong Zhao
  • Publication number: 20190025324
    Abstract: Method and system for sequence analysis directly on a solid surface that is both high speed and high throughput are described herein, utilizing equipment available in most protein analysis facilities. For example, surface bound peptides, selectively labeled at their N-termini with a positive charge-bearing group, are subjected to controlled degradation in ammonia gas, resulting in a concatenated set of charged peptide fragments that differ by a single amino acid. The fragments are taken up in a small volume of matrix solution and analyzed by matrix assisted laser desorption/ionization (MALDI) mass spectrometry. The peptide sequences can be read directly from the resulting spectra.
    Type: Application
    Filed: July 20, 2018
    Publication date: January 24, 2019
    Inventor: Zhan-Gong Zhao
  • Publication number: 20180259510
    Abstract: The present application provides arrays for use in immunosignaturing and quality control of such arrays. Also disclosed are peptide arrays and uses thereof for diagnostics, therapeutics and research.
    Type: Application
    Filed: May 11, 2018
    Publication date: September 13, 2018
    Inventors: Neal WOODBURY, Stephen JOHNSTON, Zhan Gong ZHAO, Matthew GREVING
  • Patent number: 10011649
    Abstract: Composition of synbodies that bind influenza. The synbodies are composed of two peptides joined on a scaffold.
    Type: Grant
    Filed: August 25, 2014
    Date of Patent: July 3, 2018
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Christopher Diehnelt, Nidhi Gupta, Valeriy Domenyuk, Zhan-Gong Zhao, Stephen Johnston
  • Patent number: 9970932
    Abstract: The present application provides arrays for use in immunosignaturing and quality control of such arrays. Also disclosed are peptide arrays and uses thereof for diagnostics, therapeutics and research.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: May 15, 2018
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Neal Woodbury, Stephen Johnston, Zhan Gong Zhao, Matthew Greving
  • Publication number: 20160207984
    Abstract: Composition of synbodies that bind influenza. The synbodies are composed of two peptides joined on a scaffold.
    Type: Application
    Filed: August 25, 2014
    Publication date: July 21, 2016
    Applicant: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Christopher DIEHNELT, Nidhi GUPTA, Valeriy DOMENYUK, Zhan-Gong ZHAO, Stephen JOHNSTON
  • Publication number: 20160041158
    Abstract: The present application provides arrays for use in immunosignaturing and quality control of such arrays. Also disclosed are peptide arrays and uses thereof for diagnostics, therapeutics and research.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 11, 2016
    Inventors: Neal WOODBURY, Stephen JOHNSTON, Zhan Gong ZHAO, Matthew GREVING
  • Publication number: 20120316078
    Abstract: Methods for producing polypeptides in vitro are described that use free template nucleic acids that are not immobilized on a substrate. Polypeptides that are produced can be captured on particles without the use of capture agents and can be used to produce polypeptide arrays.
    Type: Application
    Filed: June 8, 2012
    Publication date: December 13, 2012
    Inventors: Kathryn F. Sykes, Zhan-Gong Zhao, Stephen Albert Johnston, Andrey Loskutov
  • Publication number: 20120065123
    Abstract: Methods for synthetic antibodies, methods for making synthetic antibodies, methods for identifying ligands, and related methods and reagents.
    Type: Application
    Filed: March 23, 2010
    Publication date: March 15, 2012
    Inventors: Stephen A. Johnston, Neal Woodbury, Christopher Diehnelt, Paul Belcher, Nidhi Gupta, Zhan-Gong Zhao, Matthew Greving, Jack Emery, Hao Yan, John Chaput
  • Publication number: 20120021967
    Abstract: The present invention provides methods for synthetic antibodies, methods for making synthetic antibodies, methods for identifying ligands, and related methods and reagents.
    Type: Application
    Filed: April 23, 2009
    Publication date: January 26, 2012
    Applicant: Arizona Board of Regents, A Body Corporate of the State Of Arizona Acting for and Behalf of Arizona
    Inventors: Stephen A. Johnston, Neal Woodbury, Christopher Diehnelt, Paul Belcher, Nidhi Gupta, Zhan-Gong Zhao, Matthew Greving, Jack Emery