Abstract: Method and system for retrieving advertisement information. Information characterizing a user's past search behavior is utilized in creating index data that associate individual users to advertisements. When a search request from a user is received, the index data are utilized to identify one or more advertisements with respect to the received user's search request. Such identified advertisements match the user's past search behavior.

Abstract: Geldanamycin compounds having a structure according to formula I where Q1, L, L1, R5, R6, and R11 are as defined herein, are useful for treating a disease or disorder ameliorated by inhibiting the function of extracellular heat shock protein-90.

Abstract: This invention refers to a dehumidifying and ventilating method. By this means, ascending gas membrane of the water vapor and dynamic solid film with adsorbent particles are formed due to the heat exchange between the water in the reactor of the dehumidifying chamber and the refrigerant in the condensing coil, for separating the indoor air. As a result, the water vapor and the dry air of the indoor air have different speeds when moving to the dehumidifying chamber, the movement of the dry air is delayed, and consequently the aim of dehumidifying is achieved. The dehumidifying and ventilating units in the air conditioners can combine with various indoor units to form refrigerant electric wires, The refrigerant electric wires can be used for cooling, dehumidifying, dehumidifying and ventilating, refrigerating, preparing nanoparticles for industry, freshwater recovery and seawater desalting to freshwater.

Abstract: Geldanamycin compounds having a structure according to formula I where Q1, L, L1, R5, R6, and R11 are as defined herein, are useful for treating a disease or disorder ameliorated by inhibiting the function of extracellular heat shock protein-90.

Abstract: Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.

Abstract: Geldanamycin compounds having a structure according to formula I where Q1, L, L1, R5, R6, and R11 are as defined herein, are useful for treating a disease or disorder ameliorated by inhibiting the function of extracellular heat shock protein-90.

Abstract: 2-Desmethyl ansamycins having a structure according to formula I, where R1, R2, R3, R4, R5 and R6 are as defined herein, and other 2-desmethyl ansamycins are useful as antiproliferative agents

Abstract: Antifungal compounds represented by formula I where R1, R2, R3 and R4 are as defined herein. Isolated or purified naturally occurring 20,21-dihydro ambruticin compounds. The invention also provides Sorangium cellulosum ambM, ambO, ambP, and ambS mutant strains; a recombinant Sorangium cellulosum strain that produces 24-norambruticin compounds; and a method for treating a fungal infection using a compound of this invention.

Abstract: Geldanamycin compounds having a structure according to formula I where Q1, L, L1, R5, R6, and R11 are as defined herein, are useful for treating a disease or disorder ameliorated by inhibiting the function of extracellular heat shock protein-90.

Abstract: A composite laminate bamboo sporting implement with an elongated handle having multiple layers of bamboo and an impact portion having multiple laminate layers affixed to the elongated handle suitable to strike, carry or throw a sporting object. Each of the elongated handle bamboo layers has an average thickness of 1.0 to 3.0 mm and both the handle and impact portion alternates in grain direction between adjoining bamboo layers at an angle between 30 to 90 degrees. Bamboo layers may be treated with a hydrogen peroxide solution to remove impurities and excess moisture thereby reducing the weight and maintaining the strength of the at least one impact portion bamboo layer. Additionally, at least one internal impact portion layer has at least a portion of aircraft-grade titanium alloy for strengthening the impact portion.

Abstract: Compounds having a structure according to formula I wherein the groups R1 and R4 are as defined in the specification, are useful as anti-proliferative agents.

Abstract: Compounds having a structure according to formula I wherein the groups R1 and R4 are as defined in the specification, are useful as anti-proliferative agents.

Abstract: A composite laminate bamboo sporting implement with an elongated handle having multiple layers of bamboo and an impact portion having multiple laminate layers affixed to the elongated handle suitable to strike, carry or throw a sporting object. Each of the elongated handle bamboo layers has an average thickness of 1.0 to 3.0 mm and both the handle and impact portion alternates in grain direction between adjoining bamboo layers at an angle between 30 to 90 degrees. Bamboo layers may be treated with a hydrogen peroxide solution to remove impurities and excess moisture thereby reducing the weight and maintaining the strength of the at least one impact portion bamboo layer. Additionally, at least one internal impact portion layer has at least a portion of aircraft-grade titanium alloy for strengthening the impact portion.

Abstract: Compounds having a structure according to formula I wherein the groups R1 and R4 are as defined in the specification, are useful as anti-proliferative agents.

Abstract: Compounds having a structure according to formula I wherein the groups R1 and R4 are as defined in the specification, are useful as anti-proliferative agents.

Abstract: Compounds having a structure according to formula I wherein the groups R1 and R4 are as defined in the specification, are useful as anti-proliferative agents.

Abstract: 2-Desmethyl ansamycins having a structure according to formula I, where R1, R2, R3, R4, R5 and R6 are as defined herein, and other 2-desmethyl ansamycins are useful as antiproliferative agents.