Patents by Inventor ZHANG Yifan

ZHANG Yifan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SMALL MOLECULE COMPOUND COMPOSITION THAT EFFICIENTLY INDUCES DIFFERENTIATION OF HUMAN PLURIPOTENT STEM CELLS INTO MYOCARDIAL CELLS
    Publication number: 20190032016
    Abstract: Disclosed is a small molecule compound composition that efficiently induces the differentiation of human pluripotent stem cells into myocardial cells. In particular, provided in the present invention is a small molecule compound composition. The small molecule compound composition comprises the following components: (i) an mTOR signaling pathway inhibitor; (ii) a Wnt pathway promoter; and (iii) optionally, a pharmaceutically acceptable carrier. The small molecule compound composition in the present invention can efficiently induce the differentiation of human pluripotent stem cells into myocardial cells. The preliminarily screened cardiomyocyte differentiation rate reaches up to 86%, and the optimized cardiomyocyte differentiation rate reaches up to 98.3%.
    Type: Application
    Filed: January 12, 2017
    Publication date: January 31, 2019
    Applicant: SHANGAHI INSTITUTES FOR BIOLOGICAL SCIENCES CHINESE ACADEMY OF SCIENCES
    Inventors: Qing JING, Xiaoxu QUI, Yang LIU, ZHANG Yifan