Patents by Inventor Zhanna Druzina

Zhanna Druzina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CD71 binding fibronectin type III domains
    Patent number: 12037379
    Abstract: The present disclosure relates to polypeptides, such as fibronectin type III (FN3) domains that can bind CD71, their conjugates, isolated nucleotides encoding the molecules, vectors, host-cells, as well as methods of making and using the same.
    Type: Grant
    Filed: April 14, 2022
    Date of Patent: July 16, 2024
    Assignee: ARO Biotherapeutics Company
    Inventors: Russell C. Addis, Zhanna Druzina, Robert V. Kolakowski, Steven G. Nadler, Karyn T. O'Neil, Yao Xin
  • FN3 Domain-siRNA Conjugates with Enzyme Replacement Therapy
    Publication number: 20240043844
    Abstract: The present disclosure relates to compositions, such as siRNA molecules and FN3 domains conjugated to the same, in combination with enzyme replacement therapies, as well as methods of making and using the same.
    Type: Application
    Filed: April 14, 2023
    Publication date: February 8, 2024
    Inventors: Swapnil KULKARNI, Russell C. ADDIS, Steven G. NADLER, Yao XIN, Zhanna DRUZINA, Karyn T. O'NEIL, Robert V. KOLAKOWSKI, Stephen J. ANDERSON
  • FN3 domain-siRNA conjugates and uses thereof
    Patent number: 11781138
    Abstract: The present disclosure relates to compositions, such as siRNA molecules and FN3 domains conjugated to the same, as well as methods of making and using the molecules.
    Type: Grant
    Filed: October 14, 2020
    Date of Patent: October 10, 2023
    Assignee: Aro Biotherapeutics Company
    Inventors: Russell C. Addis, Zhanna Druzina, Robert Kolakowski, Swapnil Kulkarni, Steven G. Nadler, Karyn O'Neil, Yao Xin
  • CD71 binding fibronectin type III domains
    Patent number: 11628222
    Abstract: The present disclosure relates to polypeptides, such as fibronectin type III (FN3) domains that can bind CD71, their conjugates, isolated nucleotides encoding the molecules, vectors, host-cells, as well as methods of making and using the same.
    Type: Grant
    Filed: October 14, 2020
    Date of Patent: April 18, 2023
    Assignee: ARO BIOTHERAPEUTICS COMPANY
    Inventors: Russell C. Addis, Zhanna Druzina, Robert Kolakowski, Swapnil Kulkarni, Steven G. Nadler, Karyn O'Neil, Yao Xin
  • FN3 Domain-siRNA Conjugates and Uses Thereof
    Publication number: 20220370626
    Abstract: The present disclosure relates to compositions, such as siRNA molecules and FN3 domains conjugated to the same, as well as methods of making and using the molecules.
    Type: Application
    Filed: April 14, 2022
    Publication date: November 24, 2022
    Inventors: Swapnil KULKARNI, Russell C. ADDIS, Steven G. NADLER, Yao XIN, Zhanna DRUZINA, Karyn T. O'NEIL, Robert V. KOLAKOWSKI, Stephen J. ANDERSON
  • CD71 BINDING FIBRONECTIN TYPE III DOMAINS
    Publication number: 20220332795
    Abstract: The present disclosure relates to polypeptides, such as fibronectin type III (FN3) domains that can bind CD71, their conjugates, isolated nucleotides encoding the molecules, vectors, host-cells, as well as methods of making and using the same.
    Type: Application
    Filed: April 14, 2022
    Publication date: October 20, 2022
    Inventors: Russell C. ADDIS, Zhanna DRUZINA, Robert V. KOLAKOWSKI, Steven G. NADLER, Karyn T. O'NEIL, Yao XIN
  • CD71 BINDING FIBRONECTIN TYPE III DOMAINS
    Publication number: 20210145976
    Abstract: The present disclosure relates to polypeptides, such as fibronectin type III (FN3) domains that can bind CD71, their conjugates, isolated nucleotides encoding the molecules, vectors, host-cells, as well as methods of making and using the same.
    Type: Application
    Filed: October 14, 2020
    Publication date: May 20, 2021
    Inventors: Russell C. Addis, Zhanna Druzina, Robert Kolakowski, Swapnil Kulkarni, Steven G. Nadler, Karyn O'Neil, Yao Xin
  • FN3 Domain-siRNA Conjugates and Uses Thereof
    Publication number: 20210108201
    Abstract: The present disclosure relates to compositions, such as siRNA molecules and FN3 domains conjugated to the same, as well as methods of making and using the molecules.
    Type: Application
    Filed: October 14, 2020
    Publication date: April 15, 2021
    Inventors: Russell C. Addis, Zhanna Druzina, Robert Kolakowski, Swapnil Kulkarni, Steven G. Nadler, Karyn O'Neil, Yao Xin