Patents by Inventor Zhanpeng JIANG

Zhanpeng JIANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR INHIBITING YTHDF1
    Publication number: 20240033244
    Abstract: A YTH N6-Methyladenosine RNA Binding Protein 1 (YTHDF1) attenuating agent, with a compound, and when bound to YTHDF1, the compound binds to amino acid residues 372-392, 479-494 and 526-535 of SEQ ID NO: 1. A modified antigen presenting cell (mAPC), with the mAPC being treated with a YTHDF1 attenuating agent. A composition, with a YTHDF1 attenuating agent, a mAPC treated with the YTHDF1 attenuating agent, and optionally a pharmaceutically acceptable carrier. A method for attenuating an activity of YTHDF1, by administering an effective amount of a YTHDF1 attenuating agent. A method for determining whether or not a candidate agent is a YTHDF1 attenuating agent, by contacting the candidate agent with a YTHDF1 mutant. A method for treating a disease, disorder or condition associated with an expression of an antigen in a subject in need thereof.
    Type: Application
    Filed: July 8, 2021
    Publication date: February 1, 2024
    Applicants: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES, HANGZHOU LEADING EDGE PHARMACEUTICAL LTD., SHANGHAI KANGQIAN BIOTECHNOLOGY LIMITED
    Inventors: Cheng LUO, Meng XU, Shijie CHEN, Yilin LI, Yantao CHEN, Hualiang JIANG, Kaixian CHEN, Zhanpeng JIANG