Abstract: A touch panel and a method of manufacturing the same, an electronic device are provided. The touch panel includes a bending area bent along a bending axis. It further includes: a plurality of first touch electrodes extending along a first direction; a plurality of second touch electrodes extending along a second direction; and a metal mesh pattern at least provided in the bending area. The metal mesh pattern includes a first metal mesh line extending along the first direction and connected with the first touch electrode in parallel. The second direction intersects with the first direction.

Abstract: A packet forwarding network may include spine and leaf switches that forward network traffic between end hosts. The packet forwarding network may be implemented on multiple network racks in a rack-based system. A controller may control the underlying spine and leaf switches to form on-premise virtual private cloud (VPC) resources. In particular, the controller may form enterprise VPC (EVPC) tenants, each having a virtual router that performs routing between different segments within the corresponding EVPC tenant. The different segments may separately include web, application, and database servers, as end hosts. The controller may form a system VPC tenant having a virtual system router that performs routing between different EVPC tenants. A segment in an internal VPC tenant formed by the controller and/or an external VPC tenant formed by the controller may provide external network access for one or more of the EVPC tenants.

Abstract: An FGF21 Fc fusion protein, a GLP-1 Fc fusion protein, and a combination therapeutic agent. The combination therapeutic agent consists of a first pharmaceutical composition comprising an FGF21 Fc fusion protein and a second pharmaceutical composition comprising a GLP-1 Fc fusion protein. The fusion proteins or a combination thereof is used for preventing or curing cardiovascular diseases and/or metabolic diseases; the diseases comprise obesity, diabetes, hyperlipidemia, nonalcoholic fatty liver disease, atherosclerosis, diabetic cardiomyopathy, coronary atherosclerotic cardiomyopathy, and other diseases related to insulin resistance.

Abstract: A touch substrate includes a base, a first electrode layer, a dielectric layer and a second electrode layer that are sequentially stacked on the base. The first electrode layer has first electrode regions and first auxiliary regions, and the second electrode layer has second electrode regions and second auxiliary regions. The first electrode layer includes a first mesh electrode including first mesh sub-electrodes and second mesh sub-electrodes. A region where each first mesh sub-electrode is located overlaps a second electrode region, and a region where each second mesh sub-electrode is located overlaps a second auxiliary region. The second electrode layer includes a second mesh electrode including third mesh sub-electrodes and fourth mesh electrodes. A region where each third mesh sub-electrode is located overlaps a first electrode region, and a region where the fourth mesh sub-electrode is located overlaps a first auxiliary region.

Abstract: A touch pad includes a first conductive pattern layer, a second conductive pattern layer, a first trace, a second trace, a first bonding pad, and a second bonding pad. The first conductive pattern layer includes a first touch electrode extending in a first direction. The second conductive pattern layer includes a second touch electrode extending in a second direction. A first end of the first trace is coupled to the first touch electrode, and a second end of the first trace is coupled to the first bonding pad. A first end of the second trace is coupled to the second touch electrode, and a second end of the second trace is coupled to the second bonding pad. The first direction intersects the second direction.

Abstract: A projection device and a projection picture correction method thereof are provided. When the projection device performs projection toward a projection surface, a plurality of target coordinates of a plurality of target vertexes are obtained based on a plurality of planes of the projection surface. The plurality of planes are not coplanar with each other, and the plurality of target vertexes form a target polygon. A first direction scaling process is performed respectively on a plurality of first image portions of an original trapezoidal image and a trapezoidal image block is generated. A second direction scaling process is performed respectively on a plurality of second image portions of the trapezoidal image block and a target image block aligned with the target polygon is generated. An output image including the target image block is projected onto the projection surface.

Abstract: A projection device and a projection image correction method are provided. Four target coordinates of four target vertices forming a target quadrilateral boundary are obtained. A first trapezoidal boundary is obtained according to a predetermined image boundary and a first coordinate component of each of the four target coordinates. At least one edge of the target quadrilateral boundary is extended until intersecting with at least one of two reference line segments to obtain a second trapezoidal boundary. Bases of the first trapezoidal boundary are perpendicular to bases of the second trapezoidal boundary. First direction scaling processing is performed according to the first trapezoidal boundary, and second direction scaling processing is performed according to the second trapezoidal boundary, to scale an original image into a target image block aligned with the target quadrilateral boundary in an output image. The projection device projects the output image to display a rectangular projection image.

Abstract: A projection device and a keystone correction method thereof are provided. The keystone correction method is adapted for the projection device and includes the following steps. A first image is obtained. A first line-taking position parameter is determined according to a ratio of a first target edge length to a second target edge length. At least one line of input pixels disposed in a first direction is retrieved from the first image according to the first line-taking position parameter. A first scaling process related to the first direction is performed according to at least one line of input pixels of the first image, such that a line of output pixels of a second image disposed in the first direction is generated. The projection device projects the second image onto a projection screen to display a rectangular projected image.

Abstract: The present disclosure provides a touch panel, a touch display screen, and a display apparatus. The touch panel includes a base substrate, a touch structure disposed on the base substrate, at least one shielding conductive plate, and a shielding trace connected to the at least one shielding conductive plate. An orthographic projection of an electrode control line in the touch structure on the base substrate overlaps an orthographic projection of the shielding conductive plate on the base substrate.

Abstract: A touch substrate includes a base, a first electrode layer, a dielectric layer and a second electrode layer that are sequentially stacked on the base. The first electrode layer has first electrode regions and first auxiliary regions, and the second electrode layer has second electrode regions and second auxiliary regions. The first electrode layer includes a first mesh electrode including first mesh sub-electrodes and second mesh sub-electrodes. A region where each first mesh sub-electrode is located overlaps a second electrode region, and a region where each second mesh sub-electrode is located overlaps a second auxiliary region. The second electrode layer includes a second mesh electrode including third mesh sub-electrodes and fourth mesh electrodes. A region where each third mesh sub-electrode is located overlaps a first electrode region, and a region where the fourth mesh sub-electrode is located overlaps a first auxiliary region.

Abstract: A linker peptide for constructing a fusion protein. The linker peptide comprises a flexible peptide and a rigid peptide. The flexible peptide consists of one or more flexible units. The rigid peptide consists of one or more rigid units. The flexible unit comprises two or more amino acid residues selected from Gly, Ser, Ala, and Thr. The rigid unit comprises a human chorionic gonadotropin ?-subunit carboxy-terminal peptide (CTP) bearing a plurality of glycosylation sites. The linker peptide can more effectively eliminate mutual steric hindrance of two fusion molecules, decreasing a reduction/loss of polymerization or activity resulting from improper folding of an active protein or a conformational change. On the other hand, the negatively charged, highly sialylated CTP can resist renal clearance, further prolonging a half-life of a fused molecule and enhancing bioavailability of a fused protein.

Abstract: Disclosed is a fusion protein of a mutated recombinant single-chain human coagulation factor VIII (FVIII), a preparation method therefor, and a use thereof. The fusion protein sequentially comprises, from an N-terminus to a C-terminus, a mutated single-chain human FVIII having a partially deleted B-domain, a flexible peptide linker, at least one rigid unit of a carboxyl-terminal peptide of a human chorionic gonadotropin beta subunit, and a half-life prolonging moiety (preferably an IgG Fc variant). The fusion protein has a similar biological activity to a recombinant FVIII, a prolonged active half life in vivo, and better stability in vitro and in vivo, and thus improves the pharmacokinetics and efficacy of the fusion protein.

Abstract: A fusion protein of hFGF21 or its analogs having improved pharmaceutical properties, and use of the fusion protein in preparing medicines for treating diseases, such as diabetes, obesity, non-alcoholic fatty liver disease, dyslipidemia, and/or metabolic syndrome.

Abstract: The present disclosure relates to a dual-function protein for regulating blood glucose and lipid metabolism, wherein said dual-function protein comprises a human GLP-1 analog and human FGF21. In the present disclosure, provided is a method for preparing said dual function protein, and also provided is the use of said dual-function protein in the preparation of a biological substance for treating type 2 diabetes, obesity, dyslipidemia, fatty liver disease and/or metabolic syndrome. The dual-function protein provided in the present disclosure can synergistically regulate blood glucose and lipid levels in vivo, and satisfy multiple requirements for patients with type 2 diabetes such as lowering blood glucose, relieving hepatic steatosis, reducing body weight and improving metabolic disorders of circulating lipids.

Abstract: A touch panel and a method of manufacturing the same, an electronic device are provided. The touch panel includes a bending area bent along a bending axis. It further includes: a plurality of first touch electrodes extending along a first direction; a plurality of second touch electrodes extending along a second direction; and a metal mesh pattern at least provided in the bending area. The metal mesh pattern includes a first metal mesh line extending along the first direction and connected with the first touch electrode in parallel. The second direction intersects with the first direction.

Abstract: A linker peptide for constructing a fusion protein. The linker peptide comprises a flexible peptide and a rigid peptide. The flexible peptide consists of one or more flexible units. The rigid peptide consists of one or more rigid units. The flexible unit comprises two or more amino acid residues selected from Gly, Ser, Ala, and Thr. The rigid unit comprises a human chorionic gonadotropin ?-subunit carboxy-terminal peptide (CTP) bearing a plurality of glycosylation sites. The linker peptide can more effectively eliminate mutual steric hindrance of two fusion molecules, decreasing a reduction/loss of polymerization or activity resulting from improper folding of an active protein or a conformational change. On the other hand, the negatively charged, highly sialylated CTP can resist renal clearance, further prolonging a half-life of a fused molecule and enhancing bioavailability of a fused protein.

Abstract: A touch screen, a manufacturing method thereof, and a display device. The touch screen includes: a plurality of mutually independent touch detection regions. Each touch detection region includes a plurality of strip transparent electrodes arranged along a first direction and extending along a second direction, and a plurality of mesh electrodes arranged along the second direction and extending along the first direction. The strip transparent electrodes and the mesh electrodes are insulated from each other, and the second direction is intersected with the first direction. Strip ground electrodes extending along the second direction exist between every two adjacent touch detection regions arranged along the first direction, and the strip ground electrodes and the strip transparent electrodes are disposed on the same layer.

Abstract: A touch screen, a manufacturing method thereof, and a display device. The touch screen includes: a plurality of mutually independent touch detection regions. Each touch detection region includes a plurality of strip transparent electrodes arranged along a first direction and extending along a second direction, and a plurality of mesh electrodes arranged along the second direction and extending along the first direction. The strip transparent electrodes and the mesh electrodes are insulated from each other, and the second direction is intersected with the first direction. Strip ground electrodes extending along the second direction exist between every two adjacent touch detection regions arranged along the first direction, and the strip ground electrodes and the strip transparent electrodes are disposed on the same layer.

Abstract: A packet forwarding network may include spine and leaf switches that forward network traffic between end hosts. The packet forwarding network may be implemented on multiple network racks in a rack-based system. A controller may control the underlying spine and leaf switches to form on-premise virtual private cloud (VPC) resources. In particular, the controller may form enterprise VPC (EVPC) tenants, each having a virtual router that performs routing between different segments within the corresponding EVPC tenant. The different segments may separately include web, application, and database servers, as end hosts. The controller may form a system VPC tenant having a virtual system router that performs routing between different EVPC tenants. A segment in an internal VPC tenant formed by the controller and/or an external VPC tenant formed by the controller may provide external network access for one or more of the EVPC tenants.

Abstract: The present disclosure provides a touch panel, a touch display screen, and a display apparatus. The touch panel includes a base substrate, a touch structure disposed on the base substrate, at least one shielding conductive plate, and a shielding trace connected to the at least one shielding conductive plate. An orthographic projection of an electrode control line in the touch structure on the base substrate overlaps an orthographic projection of the shielding conductive plate on the base substrate.