Patents by Inventor Zhao-Kui Wan

Zhao-Kui Wan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 11-Beta HSD 1 inhibitors
    Publication number: 20070219198
    Abstract: This invention relates to inhibiting 11?HSD1.
    Type: Application
    Filed: February 7, 2007
    Publication date: September 20, 2007
    Applicant: Wyeth
    Inventors: Jason Xiang, Eddine Saiah, Steve Tam, John Mckew, Lihren Chen, Manus Ipek, Katherine Lee, Huan-Qiu Li, Jianchang Li, Wei Li, Tarek Mansour, Vipin Suri, Richard Vargas, Yuchuan Wu, Zhao-Kui Wan, Jinbo Lee, Eva Binnun, Douglas Wilson
  • PTP1b inhibitors
    Publication number: 20060135488
    Abstract: This invention relates to modulating (e.g., inhibiting) protein tyrosine phosphatase 1B (PTP1B).
    Type: Application
    Filed: November 22, 2005
    Publication date: June 22, 2006
    Inventors: Jinbo Lee, Michael Smith, Alessandro Moretto, Zhao-Kui Wan, Eva Binnun, Weixin Xu, Kenneth Foreman, Diane Joseph-McCarthy, David Erbe, Steve Tam
  • Inhibitors of protein tyrosine phosphatase 1B
    Publication number: 20050203081
    Abstract: Protein tyrosine phosphatases (PTPases) such as PTP1B can play a role in regulating a wide variety of cellular responses such as insulin signaling. Substituted bicyclic fused-thiophene compounds can inhibit PTP1B and thereby induce greater insulin sensitivity. Accordingly, PTP1B inhibition can provide an alternate treatment for PTPase-mediated disorders such as diabetes.
    Type: Application
    Filed: February 23, 2005
    Publication date: September 15, 2005
    Inventors: Jinbo Lee, Steve Kirincich, Michael Smith, Douglas Wilson, Bruce Follows, Zhao-Kui Wan, Diane Joseph-McCarthy, David Erbe, Yan-Ling Zhang, Weixin Xu, Steve Tam
  • Inhibitors of protein tyrosine phosphatase 1B
    Publication number: 20050203087
    Abstract: Protein tyrosine phosphatases (PTPases) such as PTP1B can play a role in regulating a wide variety of cellular responses such as insulin signaling. Substituted thiophene compounds such as, for example, 2-carboxyl, 3-carboxymethoxy, 5-aryl substituted thiophenes, can inhibit PTP1B and thereby induce greater insulin sensitivity. Accordingly, PTP1B inhibition can provide an alternate treatment for PTPase-mediated disorders such as diabetes.
    Type: Application
    Filed: February 23, 2005
    Publication date: September 15, 2005
    Inventors: Jinbo Lee, Zhao-Kui Wan, Douglas Wilson, Bruce Follows, Steven Kirincich, Michael Smith, Jun-Jun Wu, Kenneth Foreman, David Erbe, Yan-Ling Zhang, Weixin Xu, Steve Tam