Patents by Inventor Zhaochun Ma

Zhaochun Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10913976
    Abstract: Novel methods of generating a localized population of immobilized clonal amplicons on a support are provided.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: February 9, 2021
    Assignee: Life Technologies Corporation
    Inventors: Bin Li, Kai Lao, Jennifer O'Neil, Jennifer Kunkel, Kellie Haley, Rachel Kasinskas, Zhaochun Ma, Pius Brzoska
  • Publication number: 20210032691
    Abstract: Novel methods of generating a localized population of immobilized clonal amplicons on a support are provided.
    Type: Application
    Filed: October 13, 2020
    Publication date: February 4, 2021
    Inventors: Bin LI, Kai Qin LAO, Jennifer O'NEIL, Jennifer KUNKEL, Kellie HALEY, Rachel KASINSKAS, Zhaochun MA, Pius BRZOSKA
  • Publication number: 20190264272
    Abstract: Novel methods of generating a localized population of immobilized clonal amplicons on a support are provided.
    Type: Application
    Filed: March 12, 2019
    Publication date: August 29, 2019
    Inventors: Bin LI, Kai Lao, Jennifer O'NEIL, Jennifer KUNKEL, Kellie HALEY, Rachel KASINSKAS, Zhaochun MA, Pius BRZOSKA
  • Patent number: 10233488
    Abstract: Novel methods of generating a localized population of immobilized clonal amplicons on a support are provided.
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: March 19, 2019
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Bin Li, Kai Qin Lao, Jennifer O'Neil, Jennifer Kunkel, Kellie Haley, Rachel Kasinskas, Zhaochun Ma, Pius Brzoska
  • Publication number: 20170305954
    Abstract: Methods for preparation of 2?,3?-dideoxynucleotides support structures, such as 2?,3?-dideoxyguanosine, 2?,3?-dideoxyadenosine, and 3?-deoxythymidine support structures are disclosed. Various methods of using such structures are also provided, such as their use for automated DNA synthesis and pyrophosphorolysis activated polymerization.
    Type: Application
    Filed: July 6, 2017
    Publication date: October 26, 2017
    Applicant: Life Technologies Corporation
    Inventors: Zhaochun Ma, Khairuzzaman Bashar Mullah, Robert G. Eason
  • Patent number: 9732112
    Abstract: Methods for preparation of 2?,3?-dideoxynucleotides support structures, such as 2?,3?-dideoxyguanosine, 2?,3?-dideoxyadenosine, and 3?-deoxythymidine support structures are disclosed. Various methods of using such structures are also provided, such as their use for automated DNA synthesis and pyrophosphorolysis activated polymerization.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: August 15, 2017
    Assignee: Life Technologies Corporation
    Inventors: Zhaochun Ma, Khairuzzaman Bashar Mullah, Robert G. Eason
  • Publication number: 20170081706
    Abstract: This disclosure relates to methods of performing activation by polyphosphorolysis (APP) reactions using at least one of the polyphosphorylating agents triphosphate, polyphosphate, imidodiphosphate, thiodiphosphate (or ?-monothiopyrophosphate), and related compounds.
    Type: Application
    Filed: September 30, 2016
    Publication date: March 23, 2017
    Inventors: Lei XI, Paul KENNEY, Zhaochun MA, Dennis PROSEN, Stephen HENDRICKS, Roland NAGEL
  • Publication number: 20170067098
    Abstract: Novel methods of generating a localized population of immobilized clonal amplicons on a support are provided.
    Type: Application
    Filed: September 26, 2016
    Publication date: March 9, 2017
    Inventors: Bin LI, Kai Qin LAO, Jennifer O'NEIL, Jennifer KUNKEL, Kellie HALEY, Rachel KASINSKAS, Zhaochun MA, Pius BRZOSKA
  • Patent number: 9575069
    Abstract: Compositions, methods and kits for labeling proteins and uses in reporter systems for detecting, quantifying and/or characterizing analytes.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: February 21, 2017
    Assignee: APPLIED BIOSYSTEMS, LLC
    Inventors: Steven Menchen, Joe Y. Lam, Zhaochun Ma, Khairuzzaman Bashar Mullah
  • Patent number: 9476080
    Abstract: Novel methods of generating a localized population of immobilized clonal amplicons on a support are provided.
    Type: Grant
    Filed: April 21, 2015
    Date of Patent: October 25, 2016
    Assignee: Life Technologies Corporation
    Inventors: Bin Li, Kai Qin Lao, Jennifer O'Neil, Jennifer Kunkel, Kellie Haley, Rachel Kasinskas, Zhaochun Ma, Pius Brzoska
  • Patent number: 9476093
    Abstract: This disclosure relates to methods of performing activation by polyphosphorolysis (APP) reactions using at least one of the polyphosphorylating agents triphosphate, polyphosphate, imidodiphosphate, thiodiphosphate (or ?-monothiopyrophosphate), and related compounds.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: October 25, 2016
    Assignee: Life Technologies Corporation
    Inventors: Lei Xi, Paul Kenney, Zhaochun Ma, Dennis Prosen, Stephen Hendricks, Roland Nagel
  • Publication number: 20160108079
    Abstract: Methods for preparation of 2?,3?-dideoxynucleotides support structures, such as 2?,3?-dideoxyguanosine, 2?,3?-dideoxyadenosine, and 3?-deoxythymidine support structures are disclosed. Various methods of using such structures are also provided, such as their use for automated DNA synthesis and pyrophosphorolysis activated polymerization.
    Type: Application
    Filed: November 25, 2015
    Publication date: April 21, 2016
    Inventors: Zhaochun MA, Khairuzzaman Bashar MULLAH, Robert G. EASON
  • Patent number: 9309566
    Abstract: In some embodiments, the present teachings provide methods for paired end sequencing. In some embodiment, a polynucleotide template to be subjected to paired end sequencing comprises at least one cross linking moiety and at least one scissile moiety. In some embodiments, a paired end sequencing reaction comprises (a) a forward sequencing step, (b) a cleavage step, and (c) a reverse sequencing step. In some embodiments, a paired end sequencing reaction comprises (a) a forward sequencing step, (b) a cross-linking step, (c) a cleavage step, and (d) a reverse sequencing step.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: April 12, 2016
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Bin Li, Kai Qin Lao, Jennifer O'Neil, Jennifer Kunkel, Kellie Haley, Rachel Kasinskas, Zhaochun Ma, Pius Brzoska
  • Patent number: 9228227
    Abstract: Methods for preparation of 2?,3?-dideoxynucleotides support structures, such as 2?,3?-dideoxyguanosine, 2?,3?-dideoxyadenosine, and 3?-deoxythymidine support structures are disclosed. Various methods of using such structures are also provided, such as their use for automated DNA synthesis and pyrophosphorolysis activated polymerization.
    Type: Grant
    Filed: February 5, 2014
    Date of Patent: January 5, 2016
    Assignee: Life Technologies Corporation
    Inventors: Zhaochun Ma, Khairuzzaman Bashar Mullah, Robert Eason
  • Publication number: 20150275284
    Abstract: Novel methods of generating a localized population of immobilized clonal amplicons on a support are provided.
    Type: Application
    Filed: April 21, 2015
    Publication date: October 1, 2015
    Inventors: Bin LI, Kai Qin LAO, Jennifer O'NEIL, Jennifer KUNKEL, Kellie HALEY, Rachel KASINSKAS, Zhaochun MA, Pius BRZOSKA
  • Publication number: 20150198605
    Abstract: Compositions, methods and kits for labeling proteins and uses in reporter systems for detecting, quantifying and/or characterizing analytes.
    Type: Application
    Filed: November 8, 2013
    Publication date: July 16, 2015
    Applicant: APPLIED BIOSYSTEMS, LLC
    Inventors: Steven MENCHEN, Joe Y. Lam, Zhaochun Ma, Khairuzzaman Bashar Mullah
  • Publication number: 20150191775
    Abstract: This disclosure relates to methods of performing activation by polyphosphorolysis (APP) reactions using at least one of the polyphosphorylating agents triphosphate, polyphosphate, imidodiphosphate, thiodiphosphate (or ?-monothiopyrophosphate), and related compounds.
    Type: Application
    Filed: January 9, 2015
    Publication date: July 9, 2015
    Inventors: Lei XI, Paul Kenney, Zhaochun Ma, Dennis Prosen, Stephen Hendricks, Roland Nagel
  • Publication number: 20150045547
    Abstract: Methods for preparation of 2?,3?-dideoxynucleotides support structures, such as 2?,3?-dideoxyguanosine, 2?,3?-dideoxyadenosine, and 3?-deoxythymidine support structures are disclosed. Various methods of using such structures are also provided, such as their use for automated DNA synthesis and pyrophosphorolysis activated polymerization.
    Type: Application
    Filed: February 5, 2014
    Publication date: February 12, 2015
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Zhaochun MA, Khairuzzaman Bashar Mullah, Robert Eason
  • Patent number: 8932813
    Abstract: This disclosure relates to methods of performing activation by polyphosphorolysis (APP) reactions using at least one of the polyphosphorylating agents triphosphate, polyphosphate, imidodiphosphate, thiodiphosphate (or ?-monothiopyrophosphate), and related compounds.
    Type: Grant
    Filed: December 13, 2011
    Date of Patent: January 13, 2015
    Assignee: Life Technologies Corporation
    Inventors: Lei (Larry) Xi, Paul Kenney, Zhaochun Ma, Dennis Prosen, Stephen Hendricks, Roland Nagel
  • Patent number: 8658776
    Abstract: Methods for preparation of 2?,3?-dideoxynucleotides support structures, such as 2?,3?-dideoxyguanosine, 2?,3?-dideoxyadenosine, and 3?-deoxythymidine support structures are disclosed. Various methods of using such structures are also provided, such as their use for automated DNA synthesis and pyrophosphorolysis activated polymerization.
    Type: Grant
    Filed: May 26, 2011
    Date of Patent: February 25, 2014
    Assignee: Life Technologies Corporation
    Inventors: Zhaochun Ma, Khairuzzaman Bashar Mullah, Robert G. Eason