Abstract: This invention is about a stretchable crystalline semiconductor nanowire and a preparation method. The stretchable crystalline semiconductor nanowire has a long and thin main body, a diameter of the nanowire is between 20 to 200 nm, and the nanowire has a crystalline inorganic semiconductor structure. The stretchable crystalline semiconductor nanowire has a bending structure having a plurality of stretchable units disposed along an axial direction, and the stretchable units are connected sequentially to form the stretchable crystalline semiconductor nanowire. Since the nanowire and the guided channel cross-section can be effectively adjusted, stripping and transferring onto other flexible substrates can be further performed. The method of preparing a crystalline nanowire having a spring structure has broad prospects in applications related to the fields of flexible electronics and sensors.